1 Result for "

TAC363

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TAC363" in MCE Product Catalog:

Cat. No.: HY-180376
CAS No.: 172081-08-2
Target:  

Neurokinin Receptor

Research Areas:  

Inflammation/Immunology

TAC 363 is a selective tachykinin NK-2 receptor antagonist. TAC 363 shows a rightward shift in the contractile response curve induced by Neurokinin A (HY-P0197) with a pA2 of 9.82. TAC 363 has a weak antagonistic effect on NK-1 receptors. TAC 363 can inhibit Neurokinin A-induced bronchoconstriction in guinea pigs with an ED50 of 0.3 mg/kg. TAC 363 can be used for the research of bronchial asthma .
loading...
    loading...