1 Result for "

TAK475

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TAK475" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-16274
CAS No.: 189060-13-7
Synonyms: TAK-475
Target:  

Farnesyl Transferase

Research Areas:  

Metabolic Disease

Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor, blocking the conversion of farnesyl diphosphate (FPP) to squalene in the cholesterol biosynthesis pathway . Lapaquistat acetate is effective at lowering low-density lipoprotein cholesterol, but it might cause liver damage. Lapaquistat acetate is used for hypercholesterolemia and mevalonate kinase deficiency (MKD) research .
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