1 Result for "

TH9028

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "TH9028" in MCE Product Catalog:

Cat. No.: HY-155219
CAS No.: 2379556-15-5
TH9028 is an inhibitor of MTHFD1, MTHFD2 and MTHFD2L, with IC50 values of 0.5 nM, 11 nM and 27 nM, respectively. TH9028 reduces replication fork speed, induces replication stress, triggers S-phase arrest, initiates apoptosis, impairs thymidine production, and causes erroneous uracil incorporation into DNA. TH9028 can be used in research related to acute myeloid leukemia .
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