2 Results for "

THP-1 dual reporter cells

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "THP-1 dual reporter cells" in MCE Product Catalog:

Cat. No.: HY-134375
CAS No.: 1507367-51-2
Synonyms: Cyclic Adenosine-Inosine Monophosphate
Target:  

NF-κB IFNAR

Research Areas:  

Inflammation/Immunology

cAIMP (Cyclic Adenosine-Inosine Monophosphate) is an effective synthetic cyclic dinucleotide. cAIMP activates IRF and NF-κB in the THP1 human monocyte reporter cell line (THP1-Dual). cAIMP induces the secretion of IFNs and pro-inflammatory cytokines in vitro in human blood, with an EC50 of 6.4 μmol/L .
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Cat. No.: HY-155151
CAS No.: 3052742-91-0
Target:  

RIP kinase

Research Areas:  

Inflammation/Immunology

RIPK2/3-IN-1 is a potent dual RIPK2/3 kinases inhibitor with IC50 values of 3 nM and 117 nM, respectively. RIPK2/3-IN-1 is against RIPK2 with IC50 value 14 nM in 14-TriLAN-Gly/NOD1 THP-1 cell-based NF-κB reporter assay .
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