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Results for "

TPC1

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Natural
Products

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-115686
    8-Azaadenosine
    5 Publications Verification

    		 Adenosine Deaminase Inflammation/Immunology Cancer
    8-Azaadenosine is a potent ADAR1 inhibitor and an A-to-I editing inhibitor. 8-Azaadenosine blocks RNA editing and inhibits proliferation, 3D growth, invasion, and migration in thyroid cancer cells [1] .
    8-Azaadenosine
  • HY-RS14926
    TPCN1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    TPCN1 Human Pre-designed siRNA Set A contains three designed siRNAs for TPCN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    TPCN1 Human Pre-designed siRNA Set A
    TPCN1 Human Pre-designed siRNA Set A
  • HY-N16764
    (rel)-Salcolin A

    		Necroptosis NO Synthase Neurological Disease Inflammation/Immunology Endocrinology Cancer
    (rel)-Salcolin A is a flavonoid lignan compound with anticancer, anti-inflammatory, and neuroprotective activities. (rel)-Salcolin A has IC50 values ??of 66.69 μM and 56.12 μM against anaplastic thyroid carcinoma cells (HTH83) and papillary thyroid carcinoma cells (TPC1), respectively. (rel)-Salcolin A also inhibits LPS-induced NO production with an IC50 of 14.65 μM. (rel)-Salcolin A exerts its effects by inducing necroptosis in thyroid cancer cells, inhibiting the production of the inflammatory factor NO, and protecting against glutamate-induced neuronal cell damage, with a neuroprotective E50 of 47.44 μM. (rel)-Salcolin A can be used in research related to thyroid cancer, anti-inflammation, and neuroprotection. (rel)-Salcolin A can be naturally extracted from the leaves of Casearia arborea and the stems of Zea mays (corn) [1] .
    (rel)-Salcolin A

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