1 Result for "

Tagmokitug

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Tagmokitug" in MCE Product Catalog:

Art. -Nr.: HY-P991061
CAS. Nr.: 3024486-14-1
Synonyms: CHS-114; SRF-114

Target:  

CCR

Forschungsgebiete:  

Cancer

Tagmokitug (CHS-114; SRF-114) is a fully human IgG1 antibody targeting CCR8. Tagmokitug selectively binds to human CCR8 (Kd = 502 pM) and mediates the death of CCR8-expressing cells via antibody-dependent cellular cytotoxicity and antibody-dependent cellular phagocytosis. Tagmokitug selectively eliminates intratumoral regulatory T cells, induces tumor growth inhibition, remodels the tumor immune microenvironment, and promotes the differentiation of cytotoxic CD8 + T cell subsets. Tagmokitug can be used for the research of solid tumors .
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