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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
Tenidap
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "Tenidap" in MCE Product Catalog:
Synonyms: CP-66248
Target:
Research Areas:
Tenidap (CP-66248) is an orally active dual inhibitor of 5-LOX and COX with anti-inflammatory and immunomodulatory properties. Tenidap downregulates the expression of IL-1 receptors in chondrocytes, reduces the release of pro-inflammatory cytokines such as IL-1, IL-6 and TNF-α, and inhibits MMP production and cartilage degradation. Tenidap also blocks bone resorption and leukocyte adhesion to vascular endothelium, interferes with ion and pH changes associated with mouse sperm capacitation, and selectively enhances the activity of hKir2.3 channels (EC50=1.3 μM). Tenidap is applicable to research related to rheumatoid arthritis .
Cat. No.: HY-105028R
CAS No.: 120210-48-2
Synonyms: CP-66248 (Standard)
Target:
Research Areas:
Tenidap (Standard) is the analytical standard of Tenidap. This product is intended for research and analytical applications. Tenidap, a non-steroidal anti-inflammatory drug, is a selective COX-1 inhibitor, with IC50 values of 0.03 μM and 1.2 μM for COX-1 and COX-2, respectively. Tenidap has anti-inflammatory and antirheumatic properties . Tenidap is also a specific SLC26A3 inhibitor .
Cat. No.: HY-105028A
CAS No.: 119784-94-0
Synonyms: CP-66248 sodium
Target:
Research Areas:
Tenidap is a non-steroidal anti-inflammatory active molecule and a selective inhibitor of COX-1, with IC50 values of 0.03 μM for COX-1 and 1.2 μM for COX-2. Tenidap exhibits anti-inflammatory and anti-rheumatic effects. Tenidap is a specific inhibitor of SLC26A3 .
Cat. No.: HY-105028S
CAS No.: 142741-60-4
Synonyms: CP-66248-d3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
