5 Results for "

Trabedersen

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Trabedersen" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-142118
CAS No.: 925681-61-4
Synonyms: AP 12009
Target:  

TGF-beta/Smad

Research Areas:  

Cancer

Trabedersen (AP 12009) is an orally active synthetic antisense phosphorothioate oligodeoxynucleotide that selectively targets human TGFβ2 mRNA. Trabedersen blocks TGFβ2 protein production, enters the nucleus without a transfection vector, and exerts dose-dependent antitumor effects. By reversing TGFβ2-induced immunosuppression and enhancing immune cytotoxicity, Trabedersen exhibits significant antiproliferative, antimigratory, and antimetastatic activities, with favorable safety profiles. Trabedersen is widely used in research related to various solid tumors, including anaplastic astrocytoma, glioblastoma, colorectal tumor, and melanoma .
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1
1 Cited Publications
Cat. No.: HY-142118A
Purity:  92.09%
Synonyms: AP 12009 sodium
Target:  

TGF-beta/Smad

Research Areas:  

Cancer

Trabedersen (AP 12009) sodium is an orally active synthetic antisense phosphorothioate oligodeoxynucleotide that selectively targets human TGFβ2 mRNA. Trabedersen sodium blocks TGFβ2 protein production, enters the nucleus without a transfection vector, and exerts dose-dependent antitumor effects. By reversing TGFβ2-induced immunosuppression and enhancing immune cytotoxicity, Trabedersen sodium exhibits significant antiproliferative, antimigratory, and antimetastatic activities, with favorable safety profiles. Trabedersen sodium is widely used in research related to various solid tumors, including anaplastic astrocytoma, glioblastoma, colorectal tumor, and melanoma .
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Cat. No.: HY-142118D
Target:  

Fluorescent Dye

Research Areas:  

Cancer

FAM labled Trabedersen sodiumis a FAM labled Trabedersen sodium.
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Cat. No.: HY-142118E
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Cy3 labled Trabedersen sodium is a Cy3 labled Trabedersen sodium.
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Cat. No.: HY-142118C
Target:  

TGF-beta/Smad

Research Areas:  

Cancer

Trabedersen sodium scrambled negative control is the sequence scrambled negative control of Trabedersen sodium.
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