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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
Triacylglycerol lipase
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "Triacylglycerol lipase" in MCE Product Catalog:
Target:
Research Areas:
Triacylglycerol lipase is an enzyme catalyzing the hydrolysis of triacylglycerol. Triacylglycerol lipase promotes fat decomposition, providing energy and lipid precursors for cells. Triacylglycerol lipase is used in the research of metabolic diseases such as diabetes and obesity .
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1 Cited Publications
Synonyms: trans-10,cis-12 CLA2
Research Areas:
(10E,12Z)-Octadeca-10,12-dienoic acid (trans-10,cis-12 CLA2) is an orally active PPARα activator and inhibits adipocyte differentiation. (10E,12Z)-Octadeca-10,12-dienoic acid and its downstream metabolites have various antioxidant and antitumor activities. (10E,12Z)-Octadeca-10,12-dienoic acid can induce proinflammatory cytokines and chemokines, which would lead to decreased adipogenesis and insulin resistance in adipose tissue. (10E,12Z)-Octadeca-10,12-dienoic acid can affect many aspects of milk fat synthesis. (10E,12Z)-Octadeca-10,12-dienoic acid reduces expression of lipogenic enzymes and inhibits the desaturation of fatty acids. (10E,12Z)-Octadeca-10,12-dienoic acid can reduce lipoprotein lipase (LPL) activity in cultured 3T3-L1 adipocytes and enhance triacylglycerol release from these cells. (10E,12Z)-Octadeca-10,12-dienoic acid decreases the expression of hepatic stearoyl-CoA desatyrase mRNA in mice. (10E,12Z)-Octadeca-10,12-dienoic acid is associated with changes in mucosal NF-κB and Cyclin D1 protein levels in mice .
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Lipase (MS grade) catalyzes the hydrolysis of triacylglycerols to release long-chain fatty acids in a site-specific manner. Lipase (MS grade) is involved in a variety of biological processes, from fat metabolism to cell signaling and inflammation, and can be used to study diseases such as pancreatic insufficiency, celiac disease and cystic fibrosis .
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Lipase, Pseudomonas fluorescens (Immobilized) is an immobilized biocatalyst derived from Pseudomonas fluorescens. Lipase, Pseudomonas fluorescens (Immobilized) efficiently catalyzes the hydrolysis, esterification and transesterification of triacylglycerols in solvent-free systems, and is particularly suitable for biodiesel production from soybean oil and selective modification of oils rich in EPA and DHA. Lipase, Pseudomonas fluorescens (Immobilized) exhibits optimal activity at pH 8.5 and 45°C, and retains residual activity after repeated cycles of use. Lipase, Pseudomonas fluorescens (Immobilized) is activated by Ca 2+, but inhibited by Co 2+, Ni 2+, Fe 3+, Fe 2+ and EDTA .
Target:
Carboxylesterase (CES) Free Fatty Acid Receptor Reactive Oxygen Species (ROS) Mitochondrial Metabolism Ferroptosis Apoptosis
Research Areas:
GR148672X is an inhibitor of carboxylesterase 1 (CES1) and hepatic microsomal triglyceride hydrolase (TGH). GR148672X blocks the catalytic activity of CES1, impairs the functions of triglyceride and cholesteryl ester lipase, reduces triglyceride mobilization and secretion, and decreases apolipoprotein B-100 secretion in primary rat hepatocytes. Under low-glucose conditions, GR148672X inhibits the survival of colorectal cancer cells by reducing free fatty acid availability, inducing toxic triglyceride accumulation, ROS production, mitochondrial damage, ferroptosis and apoptosis. GR148672X can be used in studies related to colorectal cancer and atherosclerosis .
Synonyms: Ethyl γ-linolenate
γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) is a polyunsaturated C18 fatty acid ethyl ester, and also serves as an acyl donor in lipase-catalyzed glycerolysis reactions. γ-Linolenic acid ethyl ester undergoes glycerolysis catalyzed by the ring-substituted Candida antarctica lipase B mutant (cp283) and wild-type Candida antarctica lipase B. γ-Linolenic acid ethyl ester can be used to support the production of triglycerides required in the pharmaceutical and cosmeceutical fields .
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Lipase, Aspergillus niger (Immobilized) is an immobilized triacylglycerol acyl hydrolase and biocatalyst. Lipase, Aspergillus niger (Immobilized) broadly catalyzes the hydrolysis of glycerol-long-chain fatty acid esters, exhibits positional selectivity for the 1,3-positions of glycerol, but shows low hydrolysis efficiency for castor oil. Lipase, Aspergillus niger (Immobilized) displays optimal activity at 45°C and pH 7.0, and remains stable at temperatures up to 60°C and over a broad pH range of 2.0-9.0. Lipase, Aspergillus niger (Immobilized) is activated by Ca 2+ and Mg 2+, but inhibited by Mn 2+, Fe 2+ and Zn 2+ .
Cat. No.: HY-157733
CAS No.: 77145-66-5
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1,2-Dioleoyl-3-behenoylglycerol (BOO) inhibits pancreatic lipase activity. 1,2-Dioleoyl-3-behenoylglycerol prevents the deposition of visceral fat and hepatic triacylglycerol (TAG) .
Cat. No.: HY-165039
CAS No.: 139979-77-4
Synonyms: 1,3-Olein-2-caprylin; 1,3-Oleoyl-2-capryloyl glycerol; TG(18:1/8:0/18:1)
Target:
Research Areas:
1,3-Dioleoyl-2-octanoyl glycerol (1,3-Olein-2-caprylin) is a triacylglycerol. 1,3-Dioleoyl-2-octanoyl glycerol can be used to characterize the functionality of R. oryzae lipase for regiodistribution analysis of fats containing medium- and short-chain fatty acids .
Cat. No.: HY-P703648
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LIPA; Triacylglycerol Ester Hydrolase; lipase A, Lysosomal Acid Type; Triacylglycerol lipase; LAL; Lysosomal Acid lipase; Sterol Esterase; Diacylglycerol lipase; CESD; Cholesteryl Esterase; Lysosomal Acid lipase/Cholesteryl Ester Hydrolase; Cholesterol Es
Species:
Human
Source:
P. pastoris
Cat. No.: HY-P70262A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIPF; HGL; lipase F, Gastric Type; lipase, Gastric; Gastric Triacylglycerol lipase; Gastric lipase; HLAL; GL
Species:
Human
Source:
HEK293
Cat. No.: HY-Y1422U
Target:
Research Areas:
Lipase, Mucor miehei (EC 3.1.1.3) is an enzyme that hydrolyzes triacylglycerols. Lipase, Mucor miehei (EC 3.1.1.3) catalyzes the reaction of triacylglycerols to diacylglycerols and carboxylates.
Cat. No.: HY-Y1422M
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Lipase,wheat germ (EC 3.1.1.3) is an enzyme that catalyses the following chemical reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
