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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
Tubulin polymerization-IN-94
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "Tubulin polymerization-IN-94" in MCE Product Catalog:
Cat. No.: HY-189398
Target:
Research Areas:
Tubulin polymerization-IN-94 is a tubulin polymerization inhibitor. Tubulin polymerization-IN-94 inhibits tubulin polymerization, forms a hydrogen bond with β-Asn349, and exhibits π-stacking with β-Lys352. Tubulin polymerization-IN-94 shows potent antiproliferative activity against multiple cancer cell lines. Tubulin polymerization-IN-94 induces G2/M cell cycle arrest, apoptosis, and disruption of the microtubule network. Tubulin polymerization-IN-94 can be used in research related to cervical cancer, gastric cancer, and breast cancer .
Cat. No.: HY-172617
CAS No.: 877810-03-2
Target:
Research Areas:
APD-94 is a dual inhibitor targeting tubulin and Bmi-1. APD-94 interfers tubulin normal polymerization. APD-94 suppresses the expression of Bmi-1. APD-94 causes cell cycle arrest at the G2/M phase in cancer cells and induces apoptosis, thus inhibiting cancer cell proliferation. APD-94 represses the growth of HT29 cell xenografts in NOD/SCID mice. APD-94 can be used for colorectal cancer study .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
