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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
UBE2M
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "UBE2M" in MCE Product Catalog:
4
4 Cited Publications
Research Areas:
NAcM-OPT is an orally bioavailable cullin neddylation 1 (DCN1) inhibitor, which potently inhibits the DCN1-UBE2M interaction .
Cat. No.: HY-RS15355
Target:
Research Areas:
UBE2M Human Pre-designed siRNA Set A contains three designed siRNAs for UBE2M gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19492
Target:
Research Areas:
Ube2m Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ube2m gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25986
Target:
Research Areas:
Ube2m Rat Pre-designed siRNA Set A contains three designed siRNAs for Ube2m gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P71406
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UBE2M; Ubiquitin Conjugating Enzyme E2 M; UBC12; NEDD8-Conjugating Enzyme Ubc12; NEDD8 Carrier Protein; HUbc12; Ubiquitin-Conjugating Enzyme E2M (UBC12 Homolog, Yeast); Ubiquitin-Conjugating Enzyme E2 M; Ubiquitin-Conjugating Enzyme E2M (Homologous To Yea
Species:
Human
Source:
E. coli
Cat. No.: HY-111505R
CAS No.: 2089293-61-6
Research Areas:
NAcM-OPT (Standard) is the analytical standard of NAcM-OPT (HY-111505). This product is intended for research and analytical applications. NAcM-OPT is an orally bioavailable cullin neddylation 1 (DCN1) inhibitor, which potently inhibits the DCN1-UBE2M interaction .
Cat. No.: HY-189074
Research Areas:
JN210 is a dual inhibitor of DCN1 and HDAC, with an IC50 of 94.26 nM against human DCN1. JN210 disrupts the UBE2M-DCN1 protein-protein interaction, blocks the neddylation modification of cullin-RING ligases, inhibits HDAC activity and induces histone hyperacetylation. JN210 impairs DNA damage repair function, induces cell apoptosis, exerts cytotoxicity and inhibits tumor growth. JN210 can be used for the research of non-small cell lung cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
