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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
ULT
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "ULT" in MCE Product Catalog:
201
201 Cited Publications
Art. -Nr.: HY-K1005
MCE Ultra High Sensitivity ECL Kit is an ultra-sensitive, luminol-based enhanced chemiluminescent substrate for detecting horseradish peroxidase (HRP) labeled antibodies on western blots. The 100 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
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Art. -Nr.: HY-147412
CAS. Nr.: 2642382-41-8
Synonyms: QR-421a
Forschungsgebiete:
Ultevursen (QR-421a) is a splice-modulating antisense oligonucleotide targeting exon 13 of the USH2A gene, which restores the functional expression of Usherin protein by inducing exon skipping. Ultevursen binds to USH2A pre-mRNA and modulates the splicing process to specifically skip exon 13 carrying the pathogenic mutation c.2299delG, generating an in-frame transcript and a truncated yet functionally normal protein. Ultevursen exhibits concentration-dependent exon skipping activity in human cells and retinal organoid models, and restores Usherin expression and retinal function in zebrafish and gene-edited mouse models. Ultevursen can be used for related research on type 2 Usher syndrome and non-syndromic retinitis pigmentosa .
Art. -Nr.: HY-W014223
CAS. Nr.: 131-56-6
Synonyms: ULTraviolet absorber UV-0
Target:
Environmental Pollutants Toll-like Receptor (TLR) NF-κB Reactive Oxygen Species (ROS) MyD88 IRAK
Forschungsgebiete:
2,4′-Dihydroxybenzophenone (Ultraviolet absorber UV-0) occupies the hydrophobic pocket of MD2 and blocks the dimerization of TLR4. 2,4′-Dihydroxybenzophenone inhibits the LPS induced mtROS production, and LPS induced inflammatory response by downregulating pro-inflammatory mediators and decreasing the expression of MyD88, p-IRAK4, and NF-κB. 2,4′-Dihydroxybenzophenone is also a UV absorber .
0 Images
RNA, (P-thio)[2′-O-(2-methoxyethyl)](A-G-m5C-m5U-m5U-m5C-G-G-A-G-A-A-A-m5U-m5U-m5U-A-A-A-m5U-m5C), sodium salt
Art. -Nr.: HY-147412A
Synonyms: QR-421a sodium
Art. -Nr.: HY-139671
CAS. Nr.: 2738334-37-5
Target:
Forschungsgebiete:
Ultrashort α,β-Peptide is found to be able to stabilize colloidal gold nanoparticles in physiological media over 3 months.
Art. -Nr.: HY-W014223R
CAS. Nr.: 131-56-6
Synonyms: ULTraviolet absorber UV-0 (Standard)
Forschungsgebiete:
2,4′-Dihydroxybenzophenone (Standard) is the analytical standard of 2,4′-Dihydroxybenzophenone. This product is intended for research and analytical applications. 2,4′-Dihydroxybenzophenone (Ultraviolet absorber UV-0) occupies the hydrophobic pocket of MD2 and blocks the dimerization of TLR4. 2,4′-Dihydroxybenzophenone inhibits the LPS induced mtROS production, and LPS induced inflammatory response by downregulating pro-inflammatory mediators and decreasing the expression of MyD88, p-IRAK4, and NF-κB. 2,4′-Dihydroxybenzophenone is also a UV absorber .
Art. -Nr.: HY-W014223S
CAS. Nr.: 2731164-01-3
Synonyms: ULTraviolet absorber UV-0-13C6
Art. -Nr.: HY-147412D
Target:
Forschungsgebiete:
FAM labled Ultevursen sodiumis a FAM labled Ultevursen sodium (HY-147412A). Ultevursen sodium (QR-421a) is a splice-modulating antisense oligonucleotide targeting exon 13 of the USH2A gene, which restores the functional expression of Usherin protein by inducing exon skipping. Ultevursen sodium binds to USH2A pre-mRNA and modulates the splicing process to specifically skip exon 13 carrying the pathogenic mutation c.2299delG, generating an in-frame transcript and a truncated yet functionally normal protein. Ultevursen sodium exhibits concentration-dependent exon skipping activity in human cells and retinal organoid models, and restores Usherin expression and retinal function in zebrafish and gene-edited mouse models. Ultevursen sodium can be used for related research on type 2 Usher syndrome and non-syndromic retinitis pigmentosa .
Art. -Nr.: HY-147412E
Target:
Forschungsgebiete:
Cy3 labled Ultevursen sodium is a Cy3 labled Ultevursen sodium (HY-147412A). Ultevursen sodium (QR-421a) is a splice-modulating antisense oligonucleotide targeting exon 13 of the USH2A gene, which restores the functional expression of Usherin protein by inducing exon skipping. Ultevursen sodium binds to USH2A pre-mRNA and modulates the splicing process to specifically skip exon 13 carrying the pathogenic mutation c.2299delG, generating an in-frame transcript and a truncated yet functionally normal protein. Ultevursen sodium exhibits concentration-dependent exon skipping activity in human cells and retinal organoid models, and restores Usherin expression and retinal function in zebrafish and gene-edited mouse models. Ultevursen sodium can be used for related research on type 2 Usher syndrome and non-syndromic retinitis pigmentosa .
0 Images
Ultevursen (sodium) scrambled negative control
Art. -Nr.: HY-147412C
Art. -Nr.: HY-184629
Ultra-small magnetic iron oxide nanoparticles refer to iron oxide (Fe3O4) nanoparticles with very small size. These nanoparticles typically have a diameter of less than 10 nanometers (<10 nm), and the size observed by TEM is usually in the range of 5-10 nm.
Art. -Nr.: HY-184628
PEGylated ultrasmall iron oxide nanoparticles (high-temperature pyrolysis method) are magnetic nanomaterials synthesized by high-temperature pyrolysis. These nanoparticles typically have a diameter of less than 10 nanometers (<10 nm), and the size observed by TEM is usually in the range of 5-10 nm.
Art. -Nr.: HY-W014223S1
CAS. Nr.: 91586-06-0
Synonyms: ULTraviolet absorber UV-0-d5
Art. -Nr.: HY-K3125
MCE Extracellular Vesicle (EV) Ultrafiltration Concentrator (500 μL, 100 kDa) features a polyethersulfone (PES) ultrafiltration membrane with a molecular weight cutoff (MWCO) of 100 kDa. It provides rapid filtration, high concentration efficiency, and high exosome recovery. Its specialized anti-dry-spin design effectively minimizes sample loss caused by excessive centrifugation and membrane drying, thereby helping maintain high exosome recovery.
Art. -Nr.: HY-W099116S
Synonyms: ULTraviolet absorbent UV-1-d3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
