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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
UNC9036
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "UNC9036" in MCE Product Catalog:
Cat. No.: HY-158048
CAS No.: 3094059-54-5
UNC9036 is a STING PROTAC degrader with a DC50 value of 227 nM. UNC9036 binds to and activates STING, recruits the VHL E3 ligase to target phosphorylated STING for ubiquitination and proteasomal degradation. UNC9036 inhibits downstream innate immune signaling events triggered by cytoplasmic DNA sensing, including IRF3 phosphorylation. UNC9036 reduces the antiviral response of cells infected with HSV-1. UNC9036 can be used in the research of renal cell carcinoma .
Cat. No.: HY-184545
CAS No.: 3055995-98-4
Research Areas:
STING ligand-5 (Compound 4) is a ligand for target protein of PROTAC, which is applicable to the synthesis of PROTAC UNC9036 (HY-158048) .
Cat. No.: HY-184551
CAS No.: 3094059-15-8
Research Areas:
(S,R,R)-VH032-CO-C8-NH2 (Compound 9) is a conjugate of an E3 ligase ligand and a linker, which can be used for the synthesis of PROTACs, such as UNC9036 (HY-158048) .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
