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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
VR1
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "VR1" in MCE Product Catalog:
8
8 Cited Publications
Target:
Áreas de investigación:
SB-366791 is a potent and selective vanilloid receptor (VR1/TRPV1) antagonist (IC50=5.7 nM). SB-366791 can be used for the research of inflammation [1] .
5
5 Cited Publications
Referencia número: HY-19960
No. CAS: 393514-24-4
Target:
Áreas de investigación:
BCTC is an orally active current inhibitor of vanilloid receptor type 1 (VR1). BCTC is a transient receptor potential cation channel subfamily M member 8 (TRPM8) and transient receptor potential vanilloid 1 (TRPV1) antagonist. BCTC is an insulin sensitizer and secretor. BCTC has anticancer and analgesic effects [1] .
Áreas de investigación:
N-Arachidonyldopamine acts as an Anandamide (HY-10863) membrane transport inhibitor, a selective CB1 cannabinoid receptor agonist, and a VR1 receptor activator. It exhibits an EC50 value of 48 nM for rat VR1 and a Ki value of 0.25 μM for CB1. N-Arachidonyldopamine exists in mammalian neural tissues. It stimulates intracellular Ca 2+ mobilization, mediates cannabinoid-like effects, and induces hypothermia, hypomotility, catalepsy, analgesia, and hyperalgesia to heat. N-Arachidonyldopamine possesses anticancer activity against breast cancer. It can be used in research related to breast cancer and heat hyperalgesia [1] .
Referencia número: HY-P1175
No. CAS: 206350-79-0
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Áreas de investigación:
Referencia número: HY-RS15121
Target:
Áreas de investigación:
TRPV1 Human Pre-designed siRNA Set A contains three designed siRNAs for TRPV1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-118299
No. CAS: 623166-14-3
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Áreas de investigación:
JYL 1511 is a partial agonist of vanilloid receptor VR1 [1].
Referencia número: HY-P1175A
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Áreas de investigación:
Referencia número: HY-130358
No. CAS: 179469-40-0
Target:
Áreas de investigación:
PDDHV is a calcium absorption inducer and may achieve 45Ca 2+ influx by stimulating vanillic acid receptor VR1. PDDHV induces 45Ca 2+ uptake (EC50: 70 nM) in rat dorsal root ganglion neurons (expressing native vanilloid receptors) and calcium mobilization (EC50: 125 nM) in VR1-transfected CHO cells. PDDHV also inhibits [3H]-resiniferatoxin (RTX) binding to the dorsal root ganglion membrane in rats [1].
Referencia número: HY-135882
No. CAS: 616884-67-4
Referencia número: HY-135881
No. CAS: 616884-66-3
Category:
Alkaloids Monophenols Neurological Disease Other Alkaloids Phenols Endogenous metabolite Disease Research Fields
Target:
Referencia número: HY-P3702
Target:
Áreas de investigación:
Referencia número: HY-19960R
No. CAS: 393514-24-4
Target:
Áreas de investigación:
BCTC (Standard) is the analytical standard of BCTC. This product is intended for research and analytical applications. BCTC is an orally active current inhibitor of vanilloid receptor type 1 (VR1). BCTC is a transient receptor potential cation channel subfamily M member 8 (TRPM8) and transient receptor potential vanilloid 1 (TRPV1) antagonist. BCTC is an insulin sensitizer and secretor. BCTC has anticancer and analgesic effects [1] .
Referencia número: HY-P1175B
Target:
Áreas de investigación:
Referencia número: HY-183857
No. CAS: 410080-55-6
Target:
Áreas de investigación:
DD-161515 is a TRPV1/VR1 inhibitor with an IC50 of 0.7 μM in rats. DD-161515 binds to an allosteric site of TRPV1 distinct from that of capsaicin, blocks channel opening, inhibits receptor-mediated calcium ion influx, reduces the excitability of peripheral sensory nerve fibers, and thereby inhibits nociception induced by heat and transmission of chemically induced pain signals. DD-161515 can be used in studies related to inflammatory pain [1] .
Referencia número: HY-RS16501
Target:
Áreas de investigación:
Trpv1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Trpv1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Category:
Alkaloids Monophenols Neurological Disease Other Alkaloids Phenols Endogenous metabolite Disease Research Fields
Target:
Referencia número: HY-103342
No. CAS: 616884-63-0
Category:
Alkaloids Monophenols Neurological Disease Other Alkaloids Phenols Endogenous metabolite Disease Research Fields
Target:
Referencia número: HY-135880
No. CAS: 616884-64-1
Category:
Alkaloids Monophenols Neurological Disease Other Alkaloids Phenols Endogenous metabolite Disease Research Fields
Target:
Referencia número: HY-135880A
No. CAS: 616884-65-2
Category:
Alkaloids Monophenols Neurological Disease Other Alkaloids Phenols Endogenous metabolite Disease Research Fields
Target:
Referencia número: HY-P87121
Synonyms: Capsaicin receptor antibody; DKFZp434K0220 antibody; osm 9 like TRP channel 1 antibody; Osm-9-like TRP channel 1 antibody; OTRPC1 antibody; Transient receptor potential cation channel subfamily V member 1 antibody; TRPV 1 antibody; Trpv1 antibody; TRPV1_HUMAN antibody; Vanilloid receptor 1 antibody; Capsaicin receptor antibody; DKFZp434K0220 antibody; osm 9 like TRP channel 1 antibody; Osm-9-like TRP channel 1 antibody; OTRPC1 antibody; Transient receptor potential cation channel subfamily V member 1 antibody; TRPV 1 antibody; Trpv1 antibody; TRPV1_HUMAN antibody; Vanilloid receptor 1 antibody; Vanilloid receptor subtype 1 antibody; VR 1 antibody; VR1 antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
