1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. TRP Channel
  3. JYL 1511

JYL 1511 is a partial agonist of vanilloid receptor VR1.

For research use only. We do not sell to patients.

JYL 1511 Chemical Structure

JYL 1511 Chemical Structure

CAS No. : 623166-14-3

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Description

JYL 1511 is a partial agonist of vanilloid receptor VR1[1].

In Vitro

JYL 1511 inhibits [3H]Resiniferatoxin binding to rat VR1 with a Ki of 50.4 nM[1].
JYL 1511 inhibits Capsaicin induction of 45Ca2+ uptake in CHO cells overexpressing rat VR1 (IC50: 3.4 nM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

435.60

Formula

C21H29N3O3S2

CAS No.
SMILES

CS(=O)(NC1=CC=C(C=C1OC)CNC(NCC2=CC=C(C=C2)C(C)(C)C)=S)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
JYL 1511
Cat. No.:
HY-118299
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