2 Results for "

VT107

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "VT107" in MCE Product Catalog:

10
10 Cited Publications
Cat. No.: HY-134957
CAS No.: 2417718-63-7
Purity:  99.89%
Target:  

YAP

Research Areas:  

Cancer

VT-107, as an analogous to VT104, is an orally active and potent pan-TEAD auto-palmitoylation inhibitor. VT-107 can be used for the research of cancer .
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Cat. No.: HY-181537
Target:  

PROTACs SNIPERs YAP IAP

Research Areas:  

Cancer

PROTAC TEAD1/IAP degrader-2 is an IAP-harnessing TEAD1 PROTAC degrader, with a DC50 of 170 nM against TEAD1 in NCI-H2052 cells. PROTAC TEAD1/IAP degrader-2 exhibits moderate antiproliferative activity in Hippo pathway-dependent mesothelioma cells. PROTAC TEAD1/IAP degrader-2 inhibits the expression of CTGF, but with a weaker effect than the TEAD inhibitor VT-107 (HY-134957). PROTAC TEAD1/IAP degrader-2 can be used in mesothelioma-related research .
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