34 Results for "

W2

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "W2" in MCE Product Catalog:

1
Arterolane
Arterolane
0 Images
1 Cited Publications
Cat. No.: HY-10852
CAS No.: 664338-39-0
Purity:  ≥98.0%
Synonyms: OZ 277; RBx 11160
Target:  

Parasite

Research Areas:  

Infection

Arterolane is an antimalarial agent, with IC50 of both 1.1 nM against P. falciparum Ro73 and W2, respectively.
1
SARS-CoV-IN-1
SARS-CoV-IN-1
0 Images
1 Cited Publications
Cat. No.: HY-135855
CAS No.: 888958-25-6
Purity:  99.88%
Target:  

SARS-CoV Parasite

Research Areas:  

Infection

SARS-CoV-IN-1 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-1 shows anti-Coronavirus activity with an EC50 of 4.9 μM in Vero cells. SARS-CoV-IN-1 inhibits the 3D7 and W2 strains of P. falciparum with IC50s of 15.4 and 133.2 nM; and IC90s of 25.7 and 459.1 nM; respectively. Antimalarial and antiviral activities .
1
SARS-CoV-IN-3
SARS-CoV-IN-3
0 Images
1 Cited Publications
Cat. No.: HY-135858
CAS No.: 888958-27-8
Purity:  99.36%
Target:  

SARS-CoV Parasite HIV

Research Areas:  

Infection

SARS-CoV-IN-3 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-3 shows anti-Coronavirus activity with an EC50 of 3.6 μM in Vero cells. SARS-CoV-IN-3 inhibits the 3D7 and W2 strains of P. falciparum with IC50s of 11.7 and 20.4 nM; and IC90s of 29.19 and 56 nM; respectively. SARS-CoV-IN-3 reduces HIV-1-induced cytopathic effect with an EC50 of 10 μM in MT-4 cells .
1
SARS-CoV-IN-2
SARS-CoV-IN-2
0 Images
1 Cited Publications
Cat. No.: HY-135856
CAS No.: 888958-26-7
Purity:  98.66%
Target:  

SARS-CoV Parasite HIV

Research Areas:  

Infection

SARS-CoV-IN-2 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-2 shows anti-Coronavirus activity with an EC50 of 1.9 μM in Vero cells. SARS-CoV-IN-2 inhibits the 3D7 and W2 strains of P. falciparum with IC50s of 21.5 and 30 nM; and IC90s of 51.0 and 99.9 nM; respectively. SARS-CoV-IN-2 reduces HIV-1-induced cytopathic effect with an EC50 of 2.9 μM in MT-4 cells. Antimalarial and Antiviral Activities .
GNF179
GNF179
0 Images
Cat. No.: HY-15975
CAS No.: 1261114-01-5
Target:  

Parasite

Research Areas:  

Infection

GNF179 is an optimized 8,8-dimethyl imidazolopiperazine analog that exhibits antimalarial potency (IC50 of 4.8 nM against the multidrug resistant strain W2). GNF179 is orally active .
8-Deoxygartanin
8-Deoxygartanin
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Cat. No.: HY-N6009
CAS No.: 33390-41-9
Category:  

Infection other families Xanthones Phenols Polyphenols Plants Disease Research Fields

Target:  

Parasite NF-κB

8-Deoxygartanin, a prenylated xanthones from G. mangostana, is a selective inhibitor of butyrylcholinesterase (BChE) . 8-Deoxygartanin exhibits antiplasmodial activity with an IC50 of 11.8 μM for the W2 strain of Plasmodium falciparum [2]. 8-Deoxygartanin inhibits NF-κB (p65) activation with an IC50 of 11.3 μM .
2-Phenylglycine
2-Phenylglycine
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Cat. No.: HY-W010248
CAS No.: 2835-06-5
Synonyms: DL-α-Phenylglycine
Category:  

Animals Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

2-Phenylglycine (DL-α-Phenylglycine) is a metabolite in breast milk during the W2 to W4 lactation period .
N-(3-Oxodecanoyl)-L-homoserine lactone
N-(3-Oxodecanoyl)-L-homoserine lactone
0 Images
Cat. No.: HY-134560
CAS No.: 147795-40-2
Purity:  99.62%
Synonyms: 3-Oxo-C10-HSL
Category:  

Microorganisms Ketones, Aldehydes, Acids

Target:  

Bacterial

N-(3-Oxodecanoyl)-L-homoserine lactone (3-Oxo-C10-HSL) is a bacterial signaling molecule with quorum-sensing agonistic activity and competitive antagonistic activity against short-chain AHLs. N-(3-Oxodecanoyl)-L-homoserine lactone binds to VanR to form a complex, activates the transcription of the vanI gene, and establishes an autoregulatory loop for its own synthesis. N-(3-Oxodecanoyl)-L-homoserine lactone inhibits the synthesis of violacein induced by short-chain AHLs. N-(3-Oxodecanoyl)-L-homoserine lactone serves as the sole carbon and nitrogen source for Rhodococcus erythropolis W2 and can be completely degraded. N-(3-Oxodecanoyl)-L-homoserine lactone can be used in studies related to bacterial infections [2] .
hDHODH-IN-13
hDHODH-IN-13
0 Images
Cat. No.: HY-149642
CAS No.: 3032611-13-2
Purity:  99.97%
Target:  

Dihydroorotate Dehydrogenase

Research Areas:  

Others

hDHODH-IN-13 (compound w2) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 value of 173.4 nM. hDHODH-IN-13 can be used in the research of IBD .
Purfalcamine
Purfalcamine
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Cat. No.: HY-117015
CAS No.: 1038620-68-6
Purity:  99.44%
Target:  

Parasite

Research Areas:  

Infection

Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes malaria parasites developmental arrest at the schizont stage [2].
Platenomycin W2
Platenomycin W2
0 Images
Cat. No.: HY-N14457
CAS No.: 52310-61-9
Category:  

Microorganisms Ketones, Aldehydes, Acids

Target:  

Antibiotic Bacterial

Platenomycin W2 is a macrolide antibiotic with anti-Gram-positive bacteria activities .
Z-Antiepilepsirine
Z-Antiepilepsirine
0 Images
Cat. No.: HY-N11031
CAS No.: 111479-04-0
Category:  

Alkaloids Piperidine Alkaloids Piper capense Piperaceae Plants

Target:  

Parasite

Z-Antiepilepsirine is an amide alkaloid that can be found in Piper capense L.f. Z-Antiepilepsirine shows antiplasmodial activity with an IC50 value of 27 µM for W2 strain of Plasmodium falciparum .
Nitidanin
Nitidanin
0 Images
Cat. No.: HY-120104
CAS No.: 171674-89-8
Synonyms: (±)-Nitidanin
Category:  

Buxaceae Lignans Phenylpropanoids Plants Buxus microphylla S.et Z.var. Sinica Rehd.et Wils.

Target:  

Parasite HCV

Nitidanin ((±)-Nitidanin) is an antimalarial and antiviral compound that can be isolated from the wood of Xanthoxylum nitidun D. C. Nitidanin is shows IC50 values of 21.2 and 18.4 μM for D6 and W2 clones of Plasmodium falciparum, respectively. Nitidanin can be used for the research of malaria and virus infection [2].
L-R4W2
L-R4W2
0 Images
Cat. No.: HY-P1175
CAS No.: 206350-79-0
Target:  

TRP Channel

Research Areas:  

Neurological Disease

L-R4W2 is a potent antagonist of vanilloid receptor 1 (VR1, TRPV1), with an IC50 of 0.1 μM. L-R4W2 may act as a potent analgesic [2].
Antimalarial agent 58
Antimalarial agent 58
0 Images
Cat. No.: HY-186055
CAS No.: 1258387-05-1
Target:  

Parasite

Research Areas:  

Infection

Antimalarial agent 58 is a diaminoquinoline methanol compound with weak in vitro activity against Plasmodium falciparum strain D6, and no activity against Plasmodium falciparum strains W2, C235 and C2A .
Antimalarial agent 47
Antimalarial agent 47
0 Images
Cat. No.: HY-170840
Target:  

Parasite

Research Areas:  

Infection

Antimalarial agent 47 (compound F14) is an antimalarial compound, with an IC50 of 235 nM for the Plasmodium falciparum W2 strain .
6-Methylhydroxyangolensate
6-Methylhydroxyangolensate
0 Images
Cat. No.: HY-N3283
CAS No.: 22255-07-8
Category:  

Khaya grandifoliola C. DC. Natural Products Plants Meliaceae

Target:  

Parasite

6-Methylhydroxyyangolensate is a limonoid can be extracted from Khaya grandifoliola. 6-Methylhydroxyyangolensate has low antimalarial activity in vitro, with an IC50 of 21.59 μg/ml against P. falciparum (W2/Indochina clone) .
Arterolane (Standard)
Arterolane (Standard)
0 Images
Cat. No.: HY-10852R
CAS No.: 664338-39-0
Synonyms: OZ 277 (Standard); RBx 11160 (Standard)
Target:  

Parasite Reference Standards

Research Areas:  

Infection

Arterolane (Standard) is the analytical standard of Arterolane. This product is intended for research and analytical applications. Arterolane is an antimalarial agent, with IC50 of both 1.1 nM against P. falciparum Ro73 and W2, respectively.
2-Phenylglycine-d5
2-Phenylglycine-d5
0 Images
Cat. No.: HY-W010248S
CAS No.: 358731-96-1
Synonyms: DL-α-Phenylglycine-d5
2-Phenylglycine-d5 is the deuterium labeled 2-Phenylglycine. 2-Phenylglycine (DL-α-Phenylglycine) is a metabolite in breast milk during the W2 to W4 lactation period .
GNF179 (Metabolite)
GNF179 (Metabolite)
0 Images
Cat. No.: HY-15980
CAS No.: 1310455-86-7
Target:  

Parasite

Research Areas:  

Infection

GNF179 metabolite is the metabolite of GNF179, which is an optimized 8,8-dimethyl IP analog that exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability.
Assay Types