Buxaceae

Cyclovirobuxine D (CVB-D) is the main active component of the traditional Chinese medicine Buxus microphylla. Cyclovirobuxine D induces autophagy and attenuates the phosphorylation of Akt and mTOR. Cyclovirobuxine D inhibits cell proliferation of gastric cancer cells through suppression of cell cycle progression and inducement of mitochondria-mediated apoptosis. Cyclovirobuxine D is beneficial for heart failure induced by myocardial infarction.

Sarsaligates A is a C₂₁-steroid ester with anticancer activity. Sarsaligates A can be used in research related to promyelocytic leukemia, gastric cancer, breast cancer, and pancreatic cancer.

Cyclovirobuxine D (Standard) is the analytical standard of Cyclovirobuxine D. This product is intended for research and analytical applications. Cyclovirobuxine D (CVB-D) is the main active component of the traditional Chinese medicine Buxus microphylla. Cyclovirobuxine D induces autophagy and attenuates the phosphorylation of Akt and mTOR. Cyclovirobuxine D inhibits cell proliferation of gastric cancer cells through suppression of cell cycle progression and inducement of mitochondria-mediated apoptosis. Cyclovirobuxine D is beneficial for heart failure induced by myocardial infarction.

Epifriedelanol acetate (Compound Ⅲc) is a nature product. Epifriedelanol acetate can be isolated from Pachysandra terminalis Sieb.

Pachysamine M (Compound 5) is a pregnane alkaloid. Pachysamine M is isolated from naturalPachysandra terminalisSieb. et Zucc.

Pachyaximine A, an alkaloid isolated from the root of Sarcococca hookeriana, has some antibacterial activity.

Nitidanin ((±)-Nitidanin) is an antimalarial and antiviral compound that can be isolated from the wood of Xanthoxylum nitidun D. C. Nitidanin is shows IC₅₀ values of 21.2 and 18.4 μM for D6 and W2 clones of Plasmodium falciparum, respectively. Nitidanin can be used for the research of malaria and virus infection.

Buxbodine B is an inhibitor for acetylcholinesterase (AChE) with an IC₅₀ of 50 μM. Buxbodine B can be used in research of Alzheimer's disease.

Demethoxyisodaphneticin is a Lignans product that can be isolated from the herbs of Buxus sinica.

6-Demethoxy-9'-deoxycleomiscosin A is a natural product.

2-Ethyl-2,6,6-trimethylpiperidin-4-one is a Alkaloids product that can be isolated from the herbs of Buxus sinica.

Axillaridine A can be isolated from Sarcococca hookeriana var. digyna. Axillaridine A inhibits the catalytic activity of AChE.