1261114-01-5
1261114-01-5
Chemical Structure
GNF179
- CAS. Nr.: 1261114-01-5
- Formula:C22H23ClFN5O
- Molecular Weight:427.90
IUPAC Name: 2-amino-1-(3-((4-chlorophenyl)amino)-2-(4-fluorophenyl)-8,8-dimethyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)ethan-1-one
InChIKey: KFSKTWYDIHJITF-UHFFFAOYSA-N
SMILES: CC1(C)C2=NC(C3=CC=C(F)C=C3)=C(NC4=CC=C(Cl)C=C4)N2CCN1C(CN)=O
Biological Activity: GNF179 is an optimized 8,8-dimethyl imidazolopiperazine analog that exhibits antimalarial potency (IC50 of 4.8 nM against the multidrug resistant strain W2). GNF179 is orally active[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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GNF179 | 99.78% | GNF179 is an optimized 8,8-dimethyl imidazolopiperazine analog that exhibits antimalarial potency (IC50 of 4.8 nM against the multidrug resistant strain W2). GNF179 is orally active. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.92
HY-108024Ganaplacide -
Similarity Score 0.91
HY-108024ARGanaplacide hydrochloride (Standard) -
Similarity Score 0.81
HY-108024BGanaplacide phosphate -
Similarity Score 0.79
HY-162696mCMQ069 -
Similarity Score 0.48
HY-170498GABA-A Receptor Ligand-1 -
Similarity Score 0.47
HY-175432p38 MAPK-IN-9 -
Similarity Score 0.46
HY-160623Rentosertib -
Similarity Score 0.46
HY-12443PF-5006739 -
Similarity Score 0.45
HY-180457GR 92549 -
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