2 Results for "

WI38 human fibroblast cells

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "WI38 human fibroblast cells" in MCE Product Catalog:

Cat. No.: HY-157404
CAS No.: 2918764-16-4
Target:  

Pim

Research Areas:  

Cancer

Pim-1/2 kinase inhibitor 2 (compound 5b) is a competitive PIM-1 and PIM-2 kinase inhibitor with IC50s of 1.31 μM and 0.67 μM, respectively. Pim-1/2 kinase inhibitor 2 shows in-vitro low cytotoxicity against normal human lung fibroblast Wi-38 cell line and potent in-vitro anticancer activity against myeloid leukaemia (NFS-60), liver (HepG-2), prostate (PC-3), and colon (Caco-2) cancer cell lines .
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Cat. No.: HY-173367
Target:  

EGFR PI3K mTOR

Research Areas:  

Cancer

Anticancer agent 271 (compound 5C) has antiproliferative activity against lung (A549), colon (Caco-2) cancer cell lines, and human lung fibroblast (WI38) with an IC50 value of 9.18 μM on A549 cells. Anticancer agent 271 downregulates PI3K and mTOR gene expression that can be used for cancer research .
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