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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
WI38VA
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "WI38VA" in MCE Product Catalog:
Cat. No.: HY-N7929
CAS No.: 40242-06-6
Category:
other families Monophenols Ketones, Aldehydes, Acids Other Phenylpropanoids Phenols Phenylpropanoids Plants Disease Research Fields Cancer
Target:
Cat. No.: HY-126311
CAS No.: 331443-00-6
Synonyms: 3,4,5,4'-Tetrahydroxystibene
Target:
Research Areas:
4-Hydroxyresveratrol (3,4,5,4'-Tetrahydroxystibene), a Resveratrol (HY-16561) analog, differentially induces pro-apoptotic p53/Bax gene expression. 4-Hydroxyresveratrol induces apoptosis in SV40 virally transformed WI38 cells (WI38VA) cells, but not in WI38 cells. 4-Hydroxyresveratrol significantly induces the expression of p53, GADD45 and Bax genes and concomitantly suppresses the expression of bcl-2 gene in WI38VA .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
