1 Result for "

X370

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "X370" in MCE Product Catalog:

Cat. No.: HY-12482
CAS No.: 1280725-80-5
Target:  

PI3K Apoptosis PDK-1 MEK Akt ERK

Research Areas:  

Cancer

X-370 is a PI3Kδ inhibitor (IC50 = 7 nM). X-370 inhibits the survival of leukemia cells, inducing G1 arrest and apoptosis. X-370 blocks PDK1 binding and phosphorylation of MEK1/2, eliminating Akt and Erk1/2 signaling. X-370 can be used in research on B-cell acute lymphoblastic leukemia (B-ALL) .
loading...
    loading...