2. Search Result
Search Result
Results for "

Z-IETD-AFC

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Fluorescent Dyes

6

Peptides

Cat. No. Nombre del producto Target Áreas de investigación Chemical Structure
  • HY-P2208
    Z-IETD-AFC

    		Fluorescent Dye Cancer
    Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity .
    Z-IETD-AFC
  • HY-120833
    Ac-Ile-Glu-Thr-Asp-pNA

    		Caspase Others
    Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity .
    Ac-Ile-Glu-Thr-Asp-pNA
  • HY-P10322
    Z-IETD-R110

    		Fluorescent Dye Cancer
    Z-IETD-R110 is a fluorescent substrate of caspases. Z-IETD-R110 acts as a substrate for caspase-8. When caspase-8 is activated, it can recognize and cut Z-IETD-R110, releasing fluorophore, which can be detected by fluorescence microscopy. Z-IETD-R110 can be used to study oxidative stress-induced apoptosis, particularly in pancreatic acinar cells .
    Z-IETD-R110
  • HY-P1169A
    Ac-IETD-AFC TFA

    		Caspase Others
    Ac-IETD-AFC TFA is a synthetic fluorogenic substrate that can be used to specifically detect caspase-8 activity. INDO 1 pentasodium is imbued with the fluorophore AFC (7-amino-4-trifluoromethylcoumarin). When caspase-8 recognizes and cleaves the amide bond following the IETD sequence in this substrate, AFC is released and emits fluorescence (Ex = ~400 nm; Em = ~505 nm) .
    Ac-IETD-AFC TFA
  • HY-P10001
    Z-IETD-pNA

    Z-Ile-Glu-Thr-Asp-pNA

    		 Caspase Cancer
    Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. Z-IETD-pNA is hydrlyzed by caspase 8 to generate pNA .
    Z-IETD-pNA
  • HY-175057
    Ac-IETD-CHO TFA

    		Apoptosis Inflammation/Immunology Cancer
    Ac-IETD-CHO TFA is a potent, reversible inhibitor of granzyme B and caspase-8. Ac-IETD-CHO TFA inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac-IETD-CHO TFA also inhibits cytotoxic T lymphocytes induced cell death .
    Ac-IETD-CHO TFA

Consulta en línea

Your information is safe with us. * Required Fields.

Saludo

  

Country or Region *

Nombre del solicitante *

 

Nombre de la Organizaciòn *

Department *

     

Direcciòn del E-mail *

 

Nombre del producto *

Cat. No.

  

Requested quantity *

Número de teléfono *

     

Observaciones

Consulta en línea

Inquiry Information

Nombre del producto:
Cat. No.:
Cantidad:
MCE Japan Authorized Agent: