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Results for "

ZWINT

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

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Recombinant Proteins

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Cat. No. Compare Product Name Species Source
  • HY-P71000
    ZWINT/ZW10 interactor Protein, Human (His)

    ZW10 Interactor; ZW10-Interacting Protein 1; ZWINT-1; ZWINT

    		 Human E. coli
    ZW10 interactor (ZWINT) is clearly involved in kinetochore function. ZWINT interacts with ZW10, a kinetochore protein, possibly regulating the association between ZW10 and kinetochores. ZWINT is required for kinetochore formation and spindle checkpoint activity and remains detectable on the kinetochore until late anaphase. ZWINT has a uniform distribution in the cytoplasm of interphase cells. ZWINT/ZW10 interactor Protein, Human (His) is the recombinant human-derived ZWINT/ZW10 interactor protein, expressed by E. coli , with N-6*His labeled tag. The total length of ZWINT/ZW10 interactor Protein, Human (His) is 277 a.a., with molecular weight of ~35 kDa.
  • HY-P71527
    ZWINT/ZW10 interactor Protein, Human (GST)

    Human ZW10 interacting protein 1; HZWINT 1; HZWINT1; KNTC 2 AP; KNTC2AP; MGC 117174; MGC117174; ZW10 interacting kinetochore protein; ZW10 interacting protein 1; ZW10 interactor; ZW10 interactor; kinetochore protein; ZW10-interacting protein 1; ZWINT 1; ZWINT; ZWINT-1; ZWINT_HUMAN; ZWINT1

    		 Human E. coli
    ZWINT, a vital MIS12 complex component, is essential for kinetochore and spindle checkpoint activity. It plays a pivotal role in ZW10 targeting to the kinetochore in prometaphase, forming interactions with ZW10, MIS12, and NDC80 subunit of the NDC80 complex. ZWINT's engagement with KNL1, CETN3, DSN1, and PMF1 underscores its multifaceted role in orchestrating kinetochore complex assembly and functionality during mitosis. ZWINT/ZW10 interactor Protein, Human (GST) is the recombinant human-derived ZWINT/ZW10 interactor protein, expressed by E. coli , with N-GST labeled tag. The total length of ZWINT/ZW10 interactor Protein, Human (GST) is 277 a.a., with molecular weight of ~58.2 kDa.

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