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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
and high-cholesterol diet
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "and high-cholesterol diet" in MCE Product Catalog:
1
1 Cited Publications
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Research Areas:
PPARγ-IN-2 (Compound 5a) is a PPARγ inhibitor. PPARγ-IN-2 inhibits TG accumulation in 3T3-L1 preadipocytes (EC50: 0.106 μM). PPARγ-IN-2 inhibits high-cholesterol diet (HFC)-induced obesity and related metabolic syndrome, and reduces lipid accumulation in adipose tissue .
Cat. No.: HY-114952
CAS No.: 185539-34-8
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SM-32504 is an effective ACAT inhibitor that can significantly reduce serum cholesterol levels in mouse models fed with high-fat and high-cholesterol diets. SM-32504 can be used for research on hypercholesterolemia and atherosclerosis .
Cat. No.: HY-120984
CAS No.: 140112-65-8
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AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol.1 Oleic acid-2,6-diisopropylanilide is an inhibitor of acylCoA:cholesterol acyltransferase with an IC50 of 7 nM.2 When co-administered to rabbits or rats fed a high fat, high cholesterol diet, oleic acid-2,6-diisopropylanilide decreased low density lipoproteins and elevated high density lipoprotein levels when administered at 0.05%.
Cat. No.: HY-AF0006
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40 kcal% Fat, 20 kcal% Fructose, and 2% Cholesterol Diet is a high-fat, high-fructose, and high-cholesterol diet that can be used to establish models of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) . Designed with similarities to Research Diets, Inc.formula D09100310.
Cat. No.: HY-AF0006A
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10 kcal% Fat Diet (Matching Sucrose to HY-AF0006) is the control diet for the 40 kcal% Fat, 20 kcal% Fructose and 2% Cholesterol Diet (HY-AF0006). The 40 kcal% Fat, 20 kcal% Fructose, and 2% Cholesterol Diet is a high-fat, high-fructose, and high-cholesterol diet that can be used to establish models of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) . Designed with similarities to Research Diets, Inc.formula D09100304.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
