38 Results for "

anti-thrombotic agent

" in MedChemExpress (MCE) Product Catalog:
Products (38)

38 Results for "anti-thrombotic agent" in MCE Product Catalog:

33
33 Publications Verification
Cat. No.: HY-17459
CAS No.: 120202-66-6
Synonyms: (S)-(+)-Clopidogrel bisulfate; (S)-(+)-Clopidogrel hydrogen sulfate
Research Areas:  

Cardiovascular Disease Cancer

Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively . Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation .Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor .
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4
4 Cited Publications
Cat. No.: HY-B1271
CAS No.: 57-96-5
Synonyms: G-28315
Research Areas:  

Inflammation/Immunology

Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects .
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1
1 Cited Publications
Cat. No.: HY-101054
CAS No.: 130089-98-4
Purity:  98.98%
Target:  

Thrombin

Research Areas:  

Cardiovascular Disease

NQ301 is an antithrombotic agent; inhibits collagen-challenged rabbit platelet aggregation with an IC50 of 10 mg/mL.
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1
1 Cited Publications
Cat. No.: HY-16991
CAS No.: 165538-40-9
Synonyms: S-18886
Terutroban (S-18886) is a selective and orally active thromboxane-prostaglandin (TP) receptor antagonist with an IC50 of 16.4 nM. Terutroban inhibits TXA2 and prostaglandin endoperoxide receptors. Terutroban is a potent antithrombotic agent and possesses anti-atherosclerotic and anti-vasoconstrictor properties .
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1
1 Cited Publications
Cat. No.: HY-16991A
CAS No.: 609340-89-8
Synonyms: S-18886 sodium
Terutroban (S-18886) sodium is a selective and orally active thromboxane-prostaglandin (TP) receptor antagonist with an IC50 of 16.4 nM. Terutroban sodium inhibits TXA2 and prostaglandin endoperoxide receptors. Terutroban sodium is a potent antithrombotic agent and possesses anti-atherosclerotic and anti-vasoconstrictor properties .
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Cat. No.: HY-P2970
CAS No.: 37189-34-7
Stem bromelain (EC 3.4.22.32) is a cysteine protease and antibacterial agent. Stem bromelain can be isolated from the stem of the pineapple (Ananas comosus). Stem bromelain induces dose-dependent secretion of IL-12p70, and IL-6, induces Apoptosis, causes cleavage of full-length PARP protein, Caspase 3, and Caspase 9, increases Bax, and decreases Bcl-2. Stem bromelain possesses various fibrinolytic, antiedema, antithrombotic, and anti-inflammatory activities. Stem bromelain also exhibits in vivo antitumor and antileukemic activities, as well as antimetastatic effects. Stem bromelain has antimycobacterial activity. Stem bromelain provides protection against lead poisoning .
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Cat. No.: HY-129611
CAS No.: 9001-00-7
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Bromelain is an anti-inflammatory agent derived from pineapple stem that acts through down-regulation of plasma kininogen, inhibition of Prostaglandin E2 expression, degradation of advanced glycation end product receptors and regulation of angiogenic biomarkers as well as antioxidant action upstream in the COX-pathway . Bromelain exhibits various fibrinolytic, antiedematous, antithrombotic, and anti-inflammatory activities. Bromelain also possesses some anticancerous activities and promotes apoptotic cell death .
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Cat. No.: HY-106784
CAS No.: 92285-01-3
Purity:  ≥99.0%
Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities .
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Cat. No.: HY-10264S
CAS No.: 1304701-57-2
Purity:  ≥99.0%
Synonyms: DU-176-d6
Edoxaban-d6 is deuterium labeled Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention. Edoxaban is also a weak inhibitor of thrombin and factor IXaβ (FIXa), with Kis of 6.00 μM and 41.7 μM, respectively, exhibits >10000-fold selectivity for FXa. Edoxaban has antithrombotic properties and has potential for thromboembolic diseases treatment .
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Cat. No.: HY-B1271R
CAS No.: 57-96-5
Synonyms: G-28315 (Standard)
Sulfinpyrazone (Standard) is the analytical standard of Sulfinpyrazone. This product is intended for research and analytical applications. Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects .
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Cat. No.: HY-P5991
CAS No.: 103951-35-5
Target:  

Inhibitory Antibodies

Research Areas:  

Cardiovascular Disease

K-Casein (106-116),bovine is an antithrombotic agent and platelet inhibitor. K-Casein (106-116),bovine binds to platelet αIIbβ3 integrin, thereby preventing fibrinogen binding. K-Casein (106-116),bovine inhibits ADP (HY-W010918)-induced platelet aggregation. K-Casein (106-116),bovine can be used in thrombosis-related research .
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Cat. No.: HY-U00383
CAS No.: 1029711-88-3
Synonyms: 3,3-Dimethylanagrelide
Research Areas:  

Cardiovascular Disease

Rafigrelide is a platelet-lowering agent, and also has antithrombotic properties.
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Cat. No.: HY-129496
CAS No.: 5397-78-4
Purity:  99.58%
Target:  

Thrombin

Research Areas:  

Cardiovascular Disease

NP-313 is a potent antithrombotic agent that inhibits platelet aggregation and activation. NP-313 has dual inhibition of thromboxane A 2 synthesis and selective inhibition of SOCC-mediated Ca 2+ inward flow .
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Cat. No.: HY-105559A
CAS No.: 52211-63-9
Purity:  99.47%
Synonyms: Quinotoxine hydrochloride
Target:  

Drug Isomer

Research Areas:  

Cardiovascular Disease

Viquidil hydrochloride (Quinotoxine hydrochloride), an isomer of Quinidine, is a cerebral vasodilator agent. Viquidil hydrochloride shows antithrombotic activity .
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Cat. No.: HY-105559
CAS No.: 84-55-9
Synonyms: Quinotoxine
Target:  

Potassium Channel

Research Areas:  

Cardiovascular Disease

Viquidil (Quinotoxine), an isomer of Quinidine, is a cerebral vasodilator agent. Viquidil shows antithrombotic activity .
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Cat. No.: HY-19052
CAS No.: 113658-85-8
Synonyms: PCA-4230
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease

Trombodipine is an antithrombotic agent, inhibiting platelet aggregation .
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Cat. No.: HY-105919
CAS No.: 120819-70-7
Target:  

Factor Xa

Research Areas:  

Cardiovascular Disease

Naroparcil is an orally active antithrombotic agent. Naroparcil exhibits antithrombotic effects in rabbit Wessler stasis model with EC50s of 21.9 mg/kg and 36.0 mg/kg after respectively intravenous injection and oral administration .
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Cat. No.: HY-P5889
CAS No.: 287964-20-9
Target:  

Thrombin

Research Areas:  

Cardiovascular Disease

Thrombin receptor peptide ligand is a thrombin receptor antagonist peptide that can be used as an antithrombotic agent .
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Cat. No.: HY-125615
CAS No.: 155158-97-7
Target:  

Glycoprotein VI

Research Areas:  

Cardiovascular Disease Others

DMP 728 methanesulfonate is a platelet glycoprotein (GP) IIb/IIIa receptor antagonist. DMP 728 methanesulfonate shows dose-dependent antiplatelet and antithrombotic effects. DMP 728 methanesulfonate can be used in the study of effective antithrombotic agents in thromboembolic diseases of coronary and peripheral arteries .
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Cat. No.: HY-117824
CAS No.: 142638-79-7
Target:  

Integrin

Research Areas:  

Others

L-703014 is a fibrinogen receptor antagonist, with the IC50 of 94 nM, that acts as a novel parenteral and potential oral antithrombotic agent .
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