142638-79-7
142638-79-7
Chemical Structure
L-703014
- CAS No.: 142638-79-7
- Formula:C24H34N4O4
- Molecular Weight:442.55
IUPAC Name: (R)-5-(1H-indol-3-yl)-3-(2-(4-(piperidin-4-yl)butanamido)acetamido)pentanoic acid
InChIKey: CEYGRENFNCKRRG-LJQANCHMSA-N
SMILES: O=C(C[C@@H](CCC1=CNC2=C1C=CC=C2)NC(CNC(CCCC3CCNCC3)=O)=O)O
Biological Activity: L-703014 is a fibrinogen receptor antagonist, with the IC50 of 94 nM, that acts as a novel parenteral and potential oral antithrombotic agent[1][2].
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L-703014 | L-703014 is a fibrinogen receptor antagonist, with the IC50 of 94 nM, that acts as a novel parenteral and potential oral antithrombotic agent. | |||||||||||||||||||||
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References
- [1]. J S Barrett, et al. Pharmacokinetics and Pharmacodynamics of L-703,014, a Potent Fibrinogen Receptor Antagonist, After Intravenous and Oral Administration in the Dog. Pharm Res. 1994 Mar;11(3):426-31. [Content Brief]
- [2]. R M Scarborough, et al. Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents. J Med Chem. 2000 Sep 21;43(19):3453-73. [Content Brief]
Keywords
