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atypical neuroleptic agent

" in MedChemExpress (MCE) Product Catalog:
Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-136280

    EMD 57445

    Sigma Receptor Neurological Disease
    Panamesine (EMD 57445) is a sigma receptor ligand, which has a high affinity (IC50 6 nM) and selectivity for sigma binding sites. Panamesine is a potential atypical neuroleptic agent .
    Panamesine
  • HY-106587A

    Clorotepine maleate salt

    Drug Derivative 5-HT Receptor Neurological Disease
    Octoclothepine (Clorotepine) maleate salt, an analog of Clozapine (HY-14539), is a neuroleptic and antipsychotic agent. Octoclothepine maleate salt exists in enantiomeric forms, where the (+)-form acts as an atypical antipsychotic, while the (-)-functions as a typical antipsychotic. (+)-Octoclothepine maleate salt exhibits extremely high binding affinity for 5-HT₆ and 5-HT₇ receptors, with Ki values of 0.41 and 0.38 nM; the Ki values of (-)-Octoclothepine maleate salt are 17.7 and 1.3 nM, respectively. Octoclothepine maleate salt can be used in research related to schizophrenia .
    Octoclothepin maleate salt
  • HY-B1196A

    Dopamine Receptor Neurological Disease
    Tiapride is a selective and orally active D2 and D3 dopamine receptors antagonist with IC50 values of 110-320 nM and 180 nM, respectively. Tiapride shows anti-dyskinetic activity and anxiolytic activity. Tiapride is a neuroleptic agent .
    Tiapride
  • HY-106587

    Clorotepine

    5-HT Receptor Drug Derivative Neurological Disease
    Octoclothepine (Clorotepine), an analog of Clozapine (HY-14539), is a neuroleptic and antipsychotic agent. Octoclothepine exists in enantiomeric forms, where the (+)-form acts as an atypical antipsychotic, while the (-)-functions as a typical antipsychotic. (+)-Octoclothepine exhibits extremely high binding affinity for 5-HT₆ and 5-HT₇ receptors, with Ki values of 0.41 and 0.38 nM; the Ki values of (-)-Octoclothepine are 17.7 and 1.3 nM, respectively. Octoclothepine can be used in research related to schizophrenia .
    Octoclothepine

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