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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
bacterial conditions
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "bacterial conditions" in MCE Product Catalog:
3
Category:
Cat. No.: HY-160238
CAS No.: 95536-41-7
Synonyms: Corynebactin
Category:
Category:
Target:
Dehydrozingerone is a ginger-derived component and cyclin D1 inhibitor that downregulates cyclin D1 expression and induces cell cycle G1 phase arrest. Dehydrozingerone reduces the proliferative capacity of castration-resistant prostate cancer cells under in vitro conditions. Dehydrozingerone reduces subcutaneous tumor growth by inhibiting cell proliferation and angiogenesis. Dehydrozingerone exerts antibacterial and antifungal activities via its α,β-unsaturated carbonyl conjugated system. Dehydrozingerone can be used in studies related to castration-resistant prostate cancer, bacterial infections, and food spoilage fungal infections .
Synonyms: Desferrioxamine E; Nocardamin
Cat. No.: HY-117778B
Purity: ≥98.0%
Target:
SF2312 ammonium is a phosphonate Antibiotic and Enolase inhibitor, with an IC50 of 18.4 nM against E. coli enolase. SF2312 ammonium reduces intracellular ATP levels and inhibits glycolytic flux. SF2312 ammonium exhibits activity against both Gram-positive and Gram-negative bacteria, and exerts synergistic effects against E. coli when combined with Fosfomycin (HY-B1075A). SF2312 ammonium shows selective toxicity toward gliomas with ENO1 gene knockout. SF2312 ammonium can be used in research related to bacterial infections and gliomas .
Cat. No.: HY-144002
CAS No.: 216014-46-9
Synonyms: RC-529
Cat. No.: HY-W704598
CAS No.: 72864-23-4
Target:
Research Areas:
Methyl 3-hydroxydodecanoate is a poly (3-hydroxyalkanoate) monomer. Methyl 3-hydroxydodecanoate can be produced with the involvement of Pseudomonas putida Bet001 .
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Research Areas:
Sulfacetamide (Standard) (Sulphacetamide (Standard)) is the analytical standard of Sulfacetamide (HY-N7123). This product is intended for research and analytical applications. Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic. Sulfacetamide has antifungal and antibacterial activities. Sulfacetamide is employed as a topical formulation in various ophthalmic, dermatological, and hair solutions against bacterial infections, acne and scalp conditions. Sulfacetamide targets bacterial folic acid synthesis and is effective against various gram-positive and gram-negative bacteria. Sulfacetamide inhibits the synthesis of both dihydro-folic acid and para-aminobenzoic acid. Sulfacetamide can be used for the study of ocular infections .
Cat. No.: HY-158905
CAS No.: 2923694-73-7
Synonyms: MTDB-Alk
Target:
MTDB-Alkyne (MTDB-Alk) is a β-coronavirus pseudoknot RNA-binding ligand that binds to the β-coronavirus pseudoknot RNA structure on the SARS-CoV-2 genome. MTDB-Alkyne can be used to synthesize Proximity-Induced Nucleic Acid Degrader (PINAD) for degrading SARS-CoV-2 RNA. MTDB-Alkyne is applicable to research related to the development of SARS-CoV-2-targeted RNA probes .
Cat. No.: HY-121120
CAS No.: 77900-75-5
Category:
Target:
Cat. No.: HY-P990801
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Cat. No.: HY-187934
CAS No.: 431058-65-0
Target:
Research Areas:
DX-619 is an antibacterial agent. DX-619 inhibits bacterial type II topoisomerases, DNA gyrase (GyrA), and topoisomerase IV (GrlA). DX-619 can be used in research related to bacterial infections, pneumonia, and other conditions .
Cat. No.: HY-E71562
Target:
Research Areas:
2-Hydroxyhexa-2,4-dienoate hydratase (EC 4.2.1.132) catalyses a late step in the bacterial steroid degradation pathway; the product, 4-hydroxy-2-oxohexanoate, forms a 2-hydroxy-4-hex-2-enolactone under acidic conditions.
Cat. No.: HY-185180
CAS No.: 14836-73-8
Target:
Research Areas:
Ferrioxamine B is a bacterial desferrioxamine siderophore produced by actinomycetes. Ferrioxamine B acts as a ligand for FpvB and FoxA, and is transported into Pseudomonas aeruginosa via the FpvB and FoxA transporters. Ferrioxamine B competitively binds to FpvB, thereby antagonizing the uptake of thiostrepton into Pseudomonas aeruginosa. Ferrioxamine B can provide an iron source to support the growth of Pseudomonas aeruginosa under iron-limiting conditions .
Cat. No.: HY-D3400
Target:
Research Areas:
CouCyCF3 is a fluorescent probe for bacterial cytoplasmic pH, with a pKa of 7.0. CouCyCF3 can be taken up by both Gram-positive and Gram-negative bacteria. Under acidic conditions, the fluorescence of CouCyCF3 in the red channel increases, while its fluorescence in the blue channel increases with elevated pH. A linear quantitative response is achieved via the I_red/I_blue ratio within the pH range of 5.0-7.5, with excitation/emission wavelengths of 445/472 nm (blue) and 640/708 nm (red). CouCyCF3 can be used for studies on bacterial acid tolerance and phagolysosome acidification .
Cat. No.: HY-K0002
MCE Bacterial Protein Extraction Reagent integrates both lysozyme and nuclease activities and is specifically formulated for E. coli lysis. It efficiently disrupts the peptidoglycan layer under mild conditions to rapidly release intracellular proteins. Simultaneously, the incorporated nucleases degrade genomic DNA/RNA, significantly reducing lysate viscosity and minimizing nucleic-acid interference, thereby preserving the native conformation and functional integrity of target proteins to the greatest extent.
Cat. No.: HY-123448
CAS No.: 854005-84-8
Target:
Research Areas:
CCG-120304 is a TonB system inhibitor and bacteriostatic agent. CCG-120304 inhibits TonB-dependent functions. CCG-120304 is applicable to research related to urinary tract infections .
Cat. No.: HY-L065
3,276 compounds
Chinese herbal therapy is an important part of Traditional Chinese Medicine (TCM). It has been used for centuries in China, where herbs are considered fundamental therapy for many acute and chronic conditions. Many studies indicated TCM exerted an overall regulatory effect via multi-component and multi-target network. Active components from Traditional Chinese Medicine possess many medicinal properties such as antioxidant, anti-cancer, and anti-bacterial effects, which makes it an important source of new drugs. Nearly 200 modern medicines have been developed either directly or indirectly from the plants used as medicines in China. For example, artemisinin, used in multidrug resistant malaria, was first isolated from the Chinese herb Artemisia annua L. Today, scientists continue to identify compounds in Chinese herbal remedies that may be useful in the development of new therapeutic agents applicable in Western medicine.
MCE designs a unique collection of 3,276 active compounds of Chinese Herbal Medicines. MCE Traditional Chinese Medicine Active Compound Library is a useful tool for discovery new drugs from TCM.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
