1 Result for "

bovine liver arginase

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "bovine liver arginase" in MCE Product Catalog:

Aureusidin
Aureusidin
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Cat. No.: HY-N9834
CAS No.: 38216-54-5
Category:  

Cyperus glomeratus L. Flavonoids Cyperaceae Extract Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Other Flavonoids

Target:  

Endogenous Metabolite Reactive Oxygen Species (ROS) Toll-like Receptor (TLR) Caspase Pyroptosis Apoptosis NF-κB Arginase Keap1-Nrf2 Heme Oxygenase (HO) p38 MAPK PGE synthase TNF Receptor NO Synthase COX

Aureusidin is a flavonoid compound that is isolated and extracted from Antirrhinum majus and exhibits oral activity. Aureusidin possesses antioxidant, neuroprotective, and anti-inflammatory properties. Aureusidin directly targets and binds MD2 and Caspase-3 with high affinity, synergistically inhibits the TLR4/NF-κB inflammatory pathway and GSDME-mediated pyroptosis, and activates the Nrf2/HO-1 antioxidant axis via the ROS/MAPKs pathway. Aureusidin is a bovine liver arginase inhibitor with an IC50 of 57.1 µM. Aureusidin is used for research on inflammation-related diseases (osteoarthritis), acute liver injury, and endothelial dysfunction .
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