23 Results for "

brain natriuretic peptide

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "brain natriuretic peptide" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-113283
CAS No.: 451-13-8
Purity:  99.46%
Homogentisic acid is an orally active, blood-brain barrier-permeable amyloidogenic compound that functions as both an amyloid component and a pigment precursor. Accumulation of homogentisic acid downregulates tight junction proteins (such as claudin-5, occludin, ZO-1) and impairs blood-brain barrier integrity. Homogentisic acid and its oxidation product benzoquinone acetic acid not only induce the aggregation and fibrosis of multiple proteins (such as 1-42, α-synuclein, SAA, Transthyretin (TTR), atrial natriuretic peptide), but also trigger oxidative stress, damage to the Wnt/β-catenin pathway, and neurotoxicity, leading to ochronosis pigment deposition and synaptic dysfunction. At specific concentrations, homogentisic acid exerts no cytotoxicity or genotoxicity on human peripheral blood lymphocytes, and even counteracts the genotoxicity induced by Irinotecan (HY-16562). Homogentisic acid serves as an important tool molecule for investigating the mechanisms of diseases including ochronosis, secondary amyloidosis, Alzheimer's disease, and colorectal cancer .
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1
1 Cited Publications
Cat. No.: HY-P84648
Synonyms: brain natriuretic peptide 32 antibody; brain type natriuretic peptide antibody; Gamma brain natriuretic peptide antibody; natriuretic peptide B antibody; natriuretic peptide precursor B antibody; natriuretic peptide, brain type antibody; natriuretic peptides B antibody; natriuretic protein antibody; NPPB antibody

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-P72805
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NPPB; PreproBNP; natriuretic peptide B; Iso-ANP; brain natriuretic Factor Prohormone; ProBNP; natriuretic peptide Precursor B; brain Type natriuretic peptide; Gamma-brain natriuretic peptide; natriuretic Protein; natriuretic peptides B; BNP
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P0003
CAS No.: 124584-08-3
Synonyms: brain natriuretic peptide-32 human; BNP-32
Nesiritide (Brain Natriuretic Peptide-32 human) is a recombinant human B-type natriuretic peptide. Nesiritide is a NPRs agonist, with Kd values of 7.3 and 13 pM for NPR-A and NPR-C, respectively. Nesiritide regulates V1/2 activation/inactivation of the L-type calcium channel. Nesiritide shows vasodilatory, diuretic, and natriuretic activities. Nesiritide is used in cardiovascular diseases such as heart failure and vascular remodeling after arterial injury .
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Cat. No.: HY-P2469
CAS No.: 1816939-52-2
Synonyms: BNP-45, mouse
Brain Natriuretic Peptide-45, mouse (BNP-45, mouse) is a 45-amino-acid peptide derived from the mouse BNP prohormone, which exhibits natriuretic, diuretic, and vasoactive effects. Brain Natriuretic Peptide-45, mouse contains all amino acid residues deemed critical for the biological activity of natriuretic peptides. Brain Natriuretic Peptide-45, mouse possesses hypotensive and diuretic activities .
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Cat. No.: HY-P1519B
Synonyms: BNP (1-32), rat acetate
Target:  

Angiotensin Receptor

Research Areas:  

Cardiovascular Disease

Brain Natriuretic Peptide (1-32), rat acetate (BNP (1-32), rat acetate) is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes) .
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Cat. No.: HY-P1573
CAS No.: 123337-89-3
Synonyms: BNP-45, rat
Brain Natriuretic Peptide-45, rat (BNP-45, rat) is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency .
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Cat. No.: HY-P1519
CAS No.: 133448-20-1
Synonyms: BNP (1-32), rat
Target:  

Angiotensin Receptor

Research Areas:  

Cardiovascular Disease

Brain Natriuretic Peptide (1-32), rat (BNP (1-32), rat) is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes) .
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Cat. No.: HY-P1573A
Synonyms: BNP-45, rat TFA
Brain Natriuretic Peptide-45, rat TFA (BNP-45, rat TFA) is a circulating form of rat brain natriuretic peptide isolated from rat heart with potent hypotensive and natriuretic potency .
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Cat. No.: HY-P0003A
CAS No.: 1684439-46-0
Synonyms: brain natriuretic peptide-32 human acetate; BNP-32 acetate
Nesiritide (Brain Natriuretic Peptide-32 human) acetate is a recombinant human B-type natriuretic peptide. Nesiritide acetate is a NPRs agonist, with Kd values of 7.3 and 13 pM for NPR-A and NPR-C, respectively. Nesiritide acetate regulates V1/2 activation/inactivation of the L-type calcium channel. Nesiritide acetate shows vasodilatory, diuretic, and natriuretic activities. Nesiritide acetate is used in cardiovascular diseases such as heart failure and vascular remodeling after arterial injury .
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Cat. No.: HY-171336
CAS No.: 357625-50-4
TRC4186 is a potent advanced glycation end-product (AGE) breaker . TRC4186 breaks advanced glycation end-products, reduces their tissue accumulation, and decreases AGE burden. TRC4186 improves endothelial and myocardial function, preserves cardiac function, retards renal dysfunction, and reduces renal dysfunction severity. TRC4186 downregulates brain natriuretic peptide and IL-6 expression. TRC4186 can be used for the research of diabetic macro- and microvascular complications, diabetic heart failure, diabetic renal failure, hypertension, diabetes, diabetic cardiomyopathy, and diabetic nephropathy .
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Cat. No.: HY-163551
The BNP peptide/KLH is an antigen-adjuvant conjugate formed by linking BNP peptide (human brain natriuretic peptide) with keyhole limpet hemocyanin (KLH). By conjugating the antigen with a protein adjuvant, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or damage the major epitopes, and it can enhance cross-presentation and the generation of antigen-specific T cells.
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Cat. No.: HY-P71119A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NPPB; PreproBNP; natriuretic peptide B; Iso-ANP; brain natriuretic Factor Prohormone; ProBNP; natriuretic peptide Precursor B; brain Type natriuretic peptide; Gamma-brain natriuretic peptide; natriuretic Protein; natriuretic peptides B; BNP
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P71119
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NPPB; PreproBNP; natriuretic peptide B; Iso-ANP; brain natriuretic Factor Prohormone; ProBNP; natriuretic peptide Precursor B; brain Type natriuretic peptide; Gamma-brain natriuretic peptide; natriuretic Protein; natriuretic peptides B; BNP
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-W092067
CAS No.: 116569-08-5
6-Hydroxyisatin is an atrial natriuretic peptide receptor (ANP receptor) inhibitor. 6-Hydroxyisatin exhibits inhibitory activity against ANP-stimulated particulate guanylyl cyclase activity in rat brain cell membranes .
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Cat. No.: HY-P71120
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NPPB; PreproBNP; natriuretic peptide B; Iso-ANP; brain natriuretic Factor Prohormone; ProBNP; natriuretic peptide Precursor B; brain Type natriuretic peptide; Gamma-brain natriuretic peptide; natriuretic Protein; natriuretic peptides B; BNP
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P706301
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ¹⁵N-NT-proBNP; ¹⁵N-N-terminal pro-B-type natriuretic peptide; ¹⁵N-ProBNP N-terminal fragment; NPPB; PreproBNP; natriuretic peptide B; Iso-ANP; brain natriuretic Factor Prohormone; ProBNP; natriuretic peptide Precursor B; brain Type natriuretic peptide; Gamma-brain natriuretic peptide; natriuretic Protein; natriuretic peptides B; BNP
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P81288
Synonyms: NPPB; natriuretic peptides B; Gamma-brain natriuretic peptide

Host:  

Mouse

Application:  

ELISA

Reactivity:  

Human

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Cat. No.: HY-P81288A
Synonyms: NPPB; natriuretic peptides B; Gamma-brain natriuretic peptide

Host:  

Mouse

Application:  

ELISA

Reactivity:  

Human

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Cat. No.: HY-P81288B
Synonyms: NPPB; natriuretic peptides B; Gamma-brain natriuretic peptide

Host:  

Mouse

Application:  

ELISA

Reactivity:  

Human

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