2 Results for "

cAIMP

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "cAIMP" in MCE Product Catalog:

Cat. No.: HY-134375
CAS No.: 1507367-51-2
Synonyms: Cyclic Adenosine-Inosine Monophosphate
Target:  

NF-κB IFNAR

Research Areas:  

Inflammation/Immunology

cAIMP (Cyclic Adenosine-Inosine Monophosphate) is an effective synthetic cyclic dinucleotide. cAIMP activates IRF and NF-κB in the THP1 human monocyte reporter cell line (THP1-Dual). cAIMP induces the secretion of IFNs and pro-inflammatory cytokines in vitro in human blood, with an EC50 of 6.4 μmol/L .
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Cat. No.: HY-112880
CAS No.: 1951464-78-0
c-(2'FdAMP-2'FdIMP) (Compound 52),a derivative of cAIMP (HY-134375), is a cyclic dinucleotide (CDN). c-(2'FdAMP-2'FdIMP) is a STING activator and significantly induce STING-dependent IRF and NF-κB pathway signaling. c-(2'FdAMP-2'FdIMP) can be used for STING-based immunotherapy, such as cancers and infectious diseases research .
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