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Results for "

carbohydrate recognition domain

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Inhibitory Antibodies

1

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-173235
    Galectin-3-IN-6

    		Galectin Cardiovascular Disease Inflammation/Immunology Cancer
    Galectin-3-IN-6 is a human and murine galectin-3 (Gal-3) inhibitor, with an IC50 of 12 nM against human galectin-3, an IC50 of 12.6 nM against mutant murine galectin-3 (V160A), and a Kd of 13 nM for human galectin-3, as well as oral bioavailability. Galectin-3-IN-6 reduces the levels of liver fibrosis markers type I collagen and α-smooth muscle actin in mouse models of acute liver injury and fibrosis. Galectin-3-IN-6 can be used for the research of acute liver injury and fibrosis .
    Galectin-3-IN-6
  • HY-163900
    Galectin-8N-IN-2

    		Galectin Others
    Galectin-8N-IN-2 (compound 2) is a potent and selective Galectin-8N inhibitor with a Ki value of 74 μM .
    Galectin-8N-IN-2
  • HY-P991813
    Anti-Mouse Ly49C Antibody (4LO3311)

    		C-type Lectin-like Receptors (CTLRs) Inflammation/Immunology
    Anti-Mouse Ly49C Antibody (4LO3311) reacts with the mouse Ly49C. Anti-Mouse Ly49C Antibody (4LO3311) recognizes an epitope located in a 32-amino acid segment of the stalk region immediately adjacent to the carbohydrate recognition domain. Recommend Isotype Controls: Mouse IgG3 kappa, Isotype Control (HY-P99985) .
    Anti-Mouse Ly49C Antibody (4LO3311)
  • HY-W069974
    Ca2+ -Langerin-IN-1

    		Calcium Channel Inflammation/Immunology
    Ca2+-Langerin-IN-1 (Compound 3) is a allosteric Langerin inhibitor. Langerin is a C-type lectin that is expressed on Langerhans cells and plays a crucial role in pathogen recognition and innate immune activation. The KD value of the CRD domain of murine Langerin protein for Ca2+-Langerin-IN-1 is 17 μM under the presence of Ca²⁺ and 53 μM under the absence of Ca²⁺ competition. Ca2+-Langerin-IN-1 induces conformational changes and competitively replaces Ca²⁺, thereby inhibiting the carbohydrate recognition function of the protein. Ca2+-Langerin-IN-1 can be used in the research of immunomodulatory therapy .
    Ca2+ -Langerin-IN-1

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