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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
40 Results for "
carbohydrate recognition domain
" in MedChemExpress (MCE) Product Catalog:
Products (40)
40 Results for "carbohydrate recognition domain" in MCE Product Catalog:
13
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Olitigaltin (TD139) is a high-affinity Galectin-3 inhibitor with a Kd value of 14 nM. Olitigaltin inhibits the activity of the AKT/β-catenin pathway, induces Apoptosis, and downregulates SREBP1 expression. Olitigaltin enhances the phosphorylation level of ERK. Olitigaltin alleviates bleomycin (HY-17565A)-induced advanced pulmonary fibrosis in mice. Olitigaltin delays the onset of diabetes, and improves glucose tolerance and serum insulin levels. Olitigaltin alleviates liver injury. Olitigaltin maintains the structure of hippocampal excitatory synapses, restores γ-wave power in the hippocampal CA1 region, inhibits hippocampal neuroinflammation, and improves cognitive function in neuroinflammation models. Olitigaltin can be used in research related to thyroid cancer, idiopathic pulmonary fibrosis, type 1 diabetes, hepatitis, and cognitive dysfunction induced by neuroinflammation .
Cat. No.: HY-173235
CAS No.: 2604662-64-6
Target:
Research Areas:
Galectin-3-IN-6 is a human and murine galectin-3 (Gal-3) inhibitor, with an IC50 of 12 nM against human galectin-3, an IC50 of 12.6 nM against mutant murine galectin-3 (V160A), and a Kd of 13 nM for human galectin-3, as well as oral bioavailability. Galectin-3-IN-6 reduces the levels of liver fibrosis markers type I collagen and α-smooth muscle actin in mouse models of acute liver injury and fibrosis. Galectin-3-IN-6 can be used for the research of acute liver injury and fibrosis .
Cat. No.: HY-163900
CAS No.: 3055149-84-0
Galectin-8N-IN-2 (compound 2) is a potent and selective Galectin-8N inhibitor with a Ki value of 74 μM .
Cat. No.: HY-P991813
Research Areas:
Cat. No.: HY-W069974
CAS No.: 79932-56-2
Target:
Research Areas:
Ca2+-Langerin-IN-1 (Compound 3) is a allosteric Langerin inhibitor. Langerin is a C-type lectin that is expressed on Langerhans cells and plays a crucial role in pathogen recognition and innate immune activation. The KD value of the CRD domain of murine Langerin protein for Ca2+-Langerin-IN-1 is 17 μM under the presence of Ca²⁺ and 53 μM under the absence of Ca²⁺ competition. Ca2+-Langerin-IN-1 induces conformational changes and competitively replaces Ca²⁺, thereby inhibiting the carbohydrate recognition function of the protein. Ca2+-Langerin-IN-1 can be used in the research of immunomodulatory therapy .
Cat. No.: HY-P70118
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4E; Macrophage-Inducible C-Type Lectin; Prev. CLECSF9; C-Type Lectin Superfamily Member 9; MINCLE; C-Type Lectin domain Family 4, Member E; C-Type Lectin domain Family 4 Member E; C-Type (Calcium Dependent, carbohydrate-recognition domain) Lectin, Sup
Species:
Human
Source:
HEK293
Cat. No.: HY-P77336
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4E; Macrophage-Inducible C-Type Lectin; Prev. CLECSF9; C-Type Lectin Superfamily Member 9; MINCLE; C-Type Lectin domain Family 4, Member E; C-Type Lectin domain Family 4 Member E; C-Type (Calcium Dependent, carbohydrate-recognition domain) Lectin, Sup
Species:
Rhesus Macaque
Source:
HEK293
Cat. No.: HY-P77336A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4E; Macrophage-Inducible C-Type Lectin; Prev. CLECSF9; C-Type Lectin Superfamily Member 9; MINCLE; C-Type Lectin domain Family 4, Member E; C-Type Lectin domain Family 4 Member E; C-Type (Calcium Dependent, carbohydrate-recognition domain) Lectin, Sup
Species:
Rhesus Macaque
Source:
HEK293
Cat. No.: HY-P706180
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4E; Macrophage-Inducible C-Type Lectin; Prev. CLECSF9; C-Type Lectin Superfamily Member 9; MINCLE; C-Type Lectin domain Family 4, Member E; C-Type Lectin domain Family 4 Member E; C-Type (Calcium Dependent, carbohydrate-recognition domain) Lectin, Superfamily Member 9
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P72014
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4C; Dendritic Lectin; Prev. CLECSF11; C-Type (Calcium Dependent, carbohydrate-recognition domain) Lectin, Superfamily Member 11; Prev. CLECSF7; C-Type Lectin domain Family 4, Member C; BDCA2; Blood Dendritic Cell Antigen 2 Protein; HECL; Blood Dendrit
Species:
Human
Source:
E. coli
Cat. No.: HY-P703697
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CLEC11A; Lymphocyte Secreted C-Type Lectin; Prev. SCGF; Osteolectin; CLECSF3; C-Type (Calcium Dependent, carbohydrate-recognition domain) Lectin, Superfamily Member 3; LSLCL; C-Type Lectin domain Family 11, Member A, Isoform CRA_c; P47; Lymphocyte Secrete
Species:
Rat
Source:
HEK293
Cat. No.: HY-P76832
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLEC3A; C-Type Lectin domain Family 3, Member A; Prev. CLECSF1; C-Type Lectin Superfamily Member 1; C-Type (Calcium Dependent, carbohydrate-recognition domain) Lectin, Superfamily Member 1 (Cartilage-Derived); Cartilage-Derived C-Type Lectin; C-Type Lecti
Species:
Mouse
Source:
Sf9 insect cells
Cat. No.: HY-P78590
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4C; Dendritic Lectin; Prev. CLECSF11; C-Type (Calcium Dependent, carbohydrate-recognition domain) Lectin, Superfamily Member 11; Prev. CLECSF7; C-Type Lectin domain Family 4, Member C; BDCA2; Blood Dendritic Cell Antigen 2 Protein; HECL; Blood Dendrit
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P700881
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4C; Dendritic Lectin; Prev. CLECSF11; C-Type (Calcium Dependent, carbohydrate-recognition domain) Lectin, Superfamily Member 11; Prev. CLECSF7; C-Type Lectin domain Family 4, Member C; BDCA2; Blood Dendritic Cell Antigen 2 Protein; HECL; Blood Dendrit
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P704542
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4C; Dendritic Lectin; Prev. CLECSF11; C-Type (Calcium Dependent, carbohydrate-recognition domain) Lectin, Superfamily Member 11; Prev. CLECSF7; C-Type Lectin domain Family 4, Member C; BDCA2; Blood Dendritic Cell Antigen 2 Protein; HECL; Blood Dendrit
Species:
Human
Source:
HEK293
Cat. No.: HY-P705469
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CLEC4C; Dendritic Lectin; Prev. CLECSF11; C-Type (Calcium Dependent, carbohydrate-recognition domain) Lectin, Superfamily Member 11; Prev. CLECSF7; C-Type Lectin domain Family 4, Member C; BDCA2; Blood Dendritic Cell Antigen 2 Protein; HECL; Blood Dendrit
Species:
Human
Source:
HEK293
Cat. No.: HY-P75677
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4F; C-Type Lectin domain Family 4, Member F; Prev. CLECSF13; C-Type Lectin 13; KCLR; CLEC4F Protein; C-Type (Calcium Dependent, carbohydrate-recognition domain) Lectin, Superfamily Member 13; KCR; FLJ39110; C-Type Lectin domain Family 4 Member F; C-Ty
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P76268
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4F; C-Type Lectin domain Family 4, Member F; Prev. CLECSF13; C-Type Lectin 13; KCLR; CLEC4F Protein; C-Type (Calcium Dependent, carbohydrate-recognition domain) Lectin, Superfamily Member 13; KCR; FLJ39110; C-Type Lectin domain Family 4 Member F; C-Ty
Species:
Rat
Source:
HEK293
Cat. No.: HY-P76269
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLEC5A; C-Type (Calcium Dependent, carbohydrate-recognition domain) Lectin, Superfamily Member 5; Prev. CLECSF5; MDL1; C-Type Lectin domain Family 5 Member A; C-Type Lectin domain Family 5, Member A; MDL-1; Myeloid DAP12-Associating Lectin-1; C-Type Lecti
Species:
Rat
Source:
HEK293
Cat. No.: HY-P77337
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLEC5A; C-Type (Calcium Dependent, carbohydrate-recognition domain) Lectin, Superfamily Member 5; Prev. CLECSF5; MDL1; C-Type Lectin domain Family 5 Member A; C-Type Lectin domain Family 5, Member A; MDL-1; Myeloid DAP12-Associating Lectin-1; C-Type Lecti
Species:
Rhesus Macaque
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
