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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
dASK 1
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "dASK 1" in MCE Product Catalog:
Cat. No.: HY-174862
CAS No.: 3064086-31-0
Research Areas:
dASK1 is a PROTAC degrader of ASK1 that recruits cereblon. dASK1 promotes ASK1 degradation in a dose- and time-dependent manner via the ubiquitin-proteasome pathway. dASK1 can be used in studies of metabolic dysfunction-associated steatohepatitis .
Cat. No.: HY-174858
CAS No.: 3100207-58-4
Research Areas:
dASK1-VHL is an ASK1 PROTAC degrader that recruits VHL. dASK1-VHL induces ubiquitination and proteasomal degradation of ASK1 by forming a ternary complex, and inhibits the downstream p38 MAPK signaling pathway. dASK1-VHL can be used in studies of metabolic dysfunction-associated steatohepatitis .
Cat. No.: HY-174860
CAS No.: 3064087-54-0
Research Areas:
ASK1 ligand 1 is a binding ligand for ASK1 and can be used to synthesize PROTACs such as dASK1-VHL (HY-174858 )[1].
Cat. No.: HY-174861
Research Areas:
(S,R,S)-AHPC-CO-C2-PEG-NHCO-C2-COOH is a synthetic E3 ubiquitin ligase ligand-linker conjugate that can be used to synthesize PROTACs such as dASK1-VHL (HY-174858) .
Cat. No.: HY-174863
CAS No.: 2376050-06-3
Research Areas:
Pomalidomide-C2-PEG-NHCO-C2-COOH is a conjugate of the CRBN ligand (HY-10984) and the linker (E3 Ligase Ligand-Linker Conjugate). Pomalidomide-C2-PEG-NHCO-C2-COOH can be used for synthesizing PROTAC ASK1 degrader dASK1 (HY-174862) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
