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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
dBAZ2
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "dBAZ2" in MCE Product Catalog:
Art. -Nr.: HY-168448
CAS. Nr.: 3104449-57-9
Target:
Forschungsgebiete:
dBAZ2 is a first-in-class BAZ2A and BAZ2B PROTAC degrader with DC50 values of 180 nM and 250 nM for BAZ2A and BAZ2B, respectively. (Blue: E3 ligase ligand (VH 101, thiol (HY-47851); Black: linker (HY-168450); pink: target protein ligand (HY-168449)) .
Art. -Nr.: HY-168449
Forschungsgebiete:
BAZ2A/B ligand 1 (compound 1) is a PROTAC target protein ligand (Ligand for Target Protein for PROTAC). BAZ2A/B ligand 1 can be used for synthesis dBAZ2 (HY-168448) .
Art. -Nr.: HY-168453
CAS. Nr.: 3104449-58-0
Target:
Forschungsgebiete:
dBAZ2B is a BAZ2B PROTAC degrader, with a DC50 of 19 nM . (Pink: BAZ2A/B ligand (HY-168449); Black: linker (HY-168450); Blue: VHL Ligand (HY-125905))
Art. -Nr.: HY-168450
CAS. Nr.: 134424-54-7
Target:
Forschungsgebiete:
trans-Cyclohexane-p-bis(C-OTs) is the linker that can be used for synthesis of PROTAC degrader dBAZ2 (HY-168448) .
Art. -Nr.: HY-168451
Forschungsgebiete:
trans-VH 101-Thiol-C-cyclohexane-p-C-OTs is the conjugate of an ligand for E3 ligase ligand and a linker, that can be used for synthesis of PROTAC degrader dBAZ2 (HY-168448) .
Art. -Nr.: HY-168454
Forschungsgebiete:
trans-VH032-Cyclopropane-F-C-cyclohexane-p-C-OTs incorporates an VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 15 can be used to design PROTACs, such as dBAZ2B (HY-168453) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
