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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4511 Results for "
dGTP-155</sub dilithium
" in MedChemExpress (MCE) Product Catalog:
Products (4511)
4511 Results for "dGTP-155</sub dilithium" in MCE Product Catalog:
34
34 Publications Verification
Cat. No.: HY-15176C
CAS No.: 2517456-88-9
Synonyms: RR82 trihydrochloride
Research Areas:
Pyridostatin (RR82) trihydrochloride is a G-quadruplex (G4) inducer/stabilizer with a Kd of 490 nM. Pyridostatin trihydrochloride also acts as an inhibitor of Zika virus (ZIKV) NS2B-NS3 protease, with an IC50 of 11.0 μM. Pyridostatin trihydrochloride interacts with G-quadruplex structures, regulates the expression of SRC and SUB1, and induces replication- and transcription-dependent DNA damage, growth arrest, and genomic instability. Pyridostatin trihydrochloride exhibits antiproliferative and antiviral activities. Pyridostatin trihydrochloride can be used in studies related to breast cancer, cervical cancer, and Zika virus infection .
34
34 Publications Verification
Synonyms: RR82 TFA
Research Areas:
Pyridostatin (RR82) TFA is a G-quadruplex (G4) inducer/stabilizer with a Kd of 490 nM. Pyridostatin TFA also acts as an inhibitor of Zika virus (ZIKV) NS2B-NS3 protease, with an IC50 of 11.0 μM. Pyridostatin TFA interacts with G-quadruplex structures, regulates the expression of SRC and SUB1, and induces replication- and transcription-dependent DNA damage, growth arrest, and genomic instability. Pyridostatin TFA exhibits antiproliferative and antiviral activities. Pyridostatin TFA can be used in studies related to breast cancer, cervical cancer, and Zika virus infection .
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24
22
22 Cited Publications
Cat. No.: HY-B0389A
CAS No.: 110187-42-3
Synonyms: Glucose-13C<sub>6sub>; D-(+)-Glucose-13C<sub>6sub>; Dextrose-13C<sub>6sub>
19
15
15 Cited Publications
Cat. No.: HY-B1455
CAS No.: 18323-44-9
Target:
Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria .
12
12 Cited Publications
Cat. No.: HY-N0390S1
CAS No.: 184161-19-1
Synonyms: L-Glutamic acid 5-amide-13C<sub>5sub>
11
11 Cited Publications
Synonyms: PA-824; (S)-PA 824
Target:
Research Areas:
Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
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10
10 Cited Publications
Synonyms: Monomethyl auristatin E-d<sub>8sub>; Deuterated labeled MMAE
7
7 Cited Publications
5
5 Cited Publications
Synonyms: Immunocytophyt-d<sub>8sub>
5
4
4 Cited Publications
Target:
Research Areas:
PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator. PZ-2891 act as an orthosteric inhibitor at high concentrations and an allosteric activator at lower sub-saturating concentrations. PZ-2891 inhibits human pantothenate kinases PANK1β, PANK2, and PANK3 with IC50s of 40.2 nM, 0.7 nM and 1.3 nM, respectively .
3
3 Cited Publications
Target:
Research Areas:
IPR-803 is a potent inhibitor of the uPAR·uPA protein-protein interaction (PPI). IPR-803 binds directly to uPAR with sub-micromolar affinity. IPR-803 displays anti-tumor activity .
3
3 Cited Publications
Cat. No.: HY-B0141S1
CAS No.: 66789-03-5
Synonyms: β-Estradiol-d<sub>4sub>; 17β-Estradiol-d<sub>4sub>; 17β-Oestradiol-d<sub>4sub>
3
3 Cited Publications
Cat. No.: HY-N0623S
CAS No.: 62595-11-3
Synonyms: Tryptophan-d<sub>5sub>; Tryptophane-d<sub>5sub>
3
2
2 Cited Publications
Cat. No.: HY-D0844S
CAS No.: 1416898-83-3
Synonyms: L-Glutathione oxidized-13C<sub>4sub>,15N<sub>2sub>; GSSG-13C<sub>4sub>,15N<sub>2sub>; Oxiglutatione-13C<sub>4sub>,15N<sub>2sub>
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
