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deoxyguanosine triphosphate

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W013159
    2'-Deoxyguanosine 5'-monophosphate disodium
    1 Publications Verification

    5′-dGMP disodium

    		 Endogenous Metabolite Nucleoside Antimetabolite/Analog Metabolic Disease
    2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .
    2'-Deoxyguanosine 5'-monophosphate disodium
  • HY-W008661
    Deoxyguanosine triphosphate trisodium solution (100 mM)
    1 Publications Verification

    dGTP trisodium solution (100 mM); 2'-deoxyguanosine-5'-triphosphate trisodium solution (100 mM)

    		 DNA/RNA Synthesis Others
    Deoxyguanosine triphosphate (dGTP) trisodium solution (100 mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification .
    Deoxyguanosine triphosphate trisodium solution (100 mM)
  • HY-138616
    dGTP

    2'-deoxyguanosine-5'-triphosphate

    		 DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Inflammation/Immunology
    dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the precursors for DNA synthesis, and serves as a direct substrate for DNA replication and repair. dGTP is prone to oxidative damage; under the action of reactive oxygen species and other factors, dGTP is oxidized to form 8-oxo-dGTP .
    dGTP
  • HY-W008661A
    Deoxyguanosine triphosphate trisodium,100 mM Solution,PCR Grade

    dGTP trisodium,100 mM Solution,PCR Grade; 2'-deoxyguanosine-5'-triphosphate trisodium,100 mM Solution,PCR Grade

    		 DNA/RNA Synthesis Others
    Deoxyguanosine triphosphate (dGTP) trisodium,100 mM Solution,PCR Grade is one of the raw materials used by DNA polymerases to synthesize long DNA strands during DNA replication. Deoxyguanosine triphosphate trisodium,100 mM Solution,PCR Grade is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied in the form of an aqueous solution .
    Deoxyguanosine triphosphate trisodium,100 mM Solution,PCR Grade
  • HY-112817
    8-Oxo-dGTP

    8-Oxo-deoxyguanosine triphosphate

    		 Apoptosis Cardiovascular Disease Neurological Disease Cancer
    8-Oxo-dGTP (8-Oxo-Deoxyguanosine triphosphate) is an oxidized guanine nucleotide formed by ROS-mediated oxidative modification of dGTP, and it also serves as a key substrate for 8-oxo-dGTP pyrophosphohydrolases (such as hMTH1 and E. coli MutT). 8-Oxo-dGTP acts as a DNA mutagen, inserts into nascent DNA and pairs with adenine and cytosine, inducing A:T to C:G transversion mutations. Furthermore, 8-Oxo-dGTP causes oxidative DNA base modification, strand breakage and S-phase arrest, and ultimately triggers AIF-mediated apoptosis and promotes spontaneous carcinogenesis in mth1-deficient mice. Accumulation of 8-Oxo-dGTP in cells induces genomic instability, but it exhibits a tumor-suppressive effect that reduces tumor incidence in mouse models instead. 8-Oxo-dGTP is widely used in studies related to spontaneous carcinogenesis, Parkinson's disease, Alzheimer's disease, heart failure and tumor mechanisms .
    8-Oxo-dGTP
  • HY-138616S3
    dGTP-13C10 dilithium

    2'-deoxyguanosine-5'-triphosphate-13C10 dilithium

    		 Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Infection Cancer
    dGTP- 13C10 (2'-Deoxyguanosine-5'-triphosphate- 13C10) dilithium is 13C-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
    dGTP-13C10 dilithium
  • HY-131605B
    Ganciclovir triphosphate disodium

    GCV-TP disodium

    		 CMV DNA/RNA Synthesis Infection Cancer
    Ganciclovir triphosphate (GCV-TP) disodium is a synthetic 2'-deoxyguanosine analog with activity in inhibiting human cytomegalovirus (CMV) replication. Ganciclovir triphosphate disodium is effective against CMV infection by binding to viral DNA polymerase and interfering with viral DNA synthesis. Ganciclovir triphosphate disodium has an IC50 of 0.01 μM against CMV strains from humans, monkeys, mice, and guinea pigs. Ganciclovir triphosphate disodium has also been used in gene-directed enzyme prodrug inhibition for cancer inhibition .
    Ganciclovir triphosphate disodium
  • HY-142028A
    Acyclovir triphosphate sodium (100 mM)

    AcycloGTP sodium (100 mM)

    		 DNA/RNA Synthesis Nucleoside Antimetabolite/Analog HIV Reverse Transcriptase Infection
    Acyclovir triphosphate (Synonyms: AcycloGTP) sodium is a Acyclovir (HY-17422) derivative that competitively inhibits viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). Acyclovir triphosphate (sodium) (100 mM) is an inhibitor of HIV-1 reverse transcriptase. Acyclovir triphosphate (sodium) (100 mM) causes termination of viral DNA synthesis .
    Acyclovir triphosphate sodium (100 mM)
  • HY-138616S4
    dGTP-13C10,15N5 dilithium

    2'-deoxyguanosine-5'-triphosphate-13C10,15N5 dilithium

    		 Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Infection Cancer
    dGTP- 13C10, 15N5 (2'-Deoxyguanosine-5'-triphosphate- 13C10, 15N5) dilithium is 13C and 15N-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
    dGTP-13C10,15N5 dilithium
  • HY-131605
    Ganciclovir triphosphate

    GCV-TP

    		 Endogenous Metabolite CMV DNA/RNA Synthesis Infection Cancer
    Ganciclovir triphosphate (GCV-TP) is a synthetic 2'-deoxyguanosine analog with activity in inhibiting human cytomegalovirus (CMV) replication. Ganciclovir triphosphate is effective against CMV infection by binding to viral DNA polymerase and interfering with viral DNA synthesis. Ganciclovir triphosphate has an IC50 of 0.01 μM against CMV strains from humans, monkeys, mice, and guinea pigs. Ganciclovir triphosphate has also been used in gene-directed enzyme prodrug inhibition for cancer inhibition .
    Ganciclovir triphosphate
  • HY-W013159S
    2'-Deoxyguanosine 5'-monophosphate-13C10,15N5 disodium

    5′-dGMP-13C10,15N5 disodium

    		 Isotope-Labeled Compounds Endogenous Metabolite Nucleoside Antimetabolite/Analog Metabolic Disease
    2'-Deoxyguanosine 5'-monophosphate- 13C10, 15N5 (dGMP- 13C10, 15N5) disodium is the 13C and 15N labeled 2'-Deoxyguanosine 5'-monophosphate disodium (HY-W013159). 2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .
    2'-Deoxyguanosine 5'-monophosphate-13C10,15N5 disodium
  • HY-W250161
    7-Deaza-2′-deoxyguanosine 5′-triphosphate

    7-Deaza-2'-dGTP

    		 Telomerase Cancer
    7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, is a telomerase inhibitor (IC50: 11 μM) .
    7-Deaza-2′-deoxyguanosine 5′-triphosphate
  • HY-134991
    3'-Deoxy-GTP

    3′-deoxyguanosine 5′-triphosphate

    		 Dengue Virus DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Infection
    3'-Deoxy-GTP (3′-Deoxyguanosine 5′-triphosphate), an analog of GTP, is a RNA chain terminator and suppresses RNA synthesis. 3'-Deoxy-GTP inhibits DENV NS5 RdRp (IC50: 0.02 μM) .
    3'-Deoxy-GTP
  • HY-138616S1
    dGTP-d14 dilithium

    2'-deoxyguanosine-5'-triphosphate-d14 dilithium

    		 Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Infection Cancer
    dGTP-d14 (2'-Deoxyguanosine-5'-triphosphate-d14) dilithium is deuterium labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
    dGTP-d14 dilithium
  • HY-134991A
    3'-Deoxy-GTP trisodium

    3′-deoxyguanosine 5′-triphosphate trisodium

    		 Dengue Virus DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Infection
    3'-Deoxy-GTP (3′-Deoxyguanosine 5′-triphosphate) trisodium, an analog of GTP, is a RNA chain terminator and suppresses RNA synthesis. 3'-Deoxy-GTP trisodium inhibits DENV NS5 RdRp (IC50: 0.02 μM) .
    3'-Deoxy-GTP trisodium
  • HY-138616S
    dGTP-15N5 dilithium

    2'-deoxyguanosine-5'-triphosphate-15N5 dilithium

    		 Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Infection Cancer
    dGTP- 15N5 (2'-Deoxyguanosine-5'-triphosphate- 15N5) dilithium is 15N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
    dGTP-15N5 dilithium
  • HY-175103
    Guanine-2'-deoxy-β-L-ribofuranosyl-5'-O-triphosphate sodium

    β-L-dGTP sodium; L-2'-deoxyguanosine 5'-triphosphate sodium; 2’-Deoxy-L-GTP sodium

    		 Telomerase Others
    Guanine-2'-deoxy-β-L-ribofuranosyl-5'-O-triphosphate (sodium) is an isomer of dGTP and an inhibitor of telomerase with a Ki of 15 μM for human enzyme .
    Guanine-2'-deoxy-β-L-ribofuranosyl-5'-O-triphosphate sodium
  • HY-138616S2
    dGTP-15N5,d14 dilithium

    2'-deoxyguanosine-5'-triphosphate-15N5,d14 dilithium

    		 Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Infection Cancer
    dGTP- 15N5,d14 (2'-Deoxyguanosine-5'-triphosphate- 15N5,d14) dilithium is deuterium and 15N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
    dGTP-15N5,d14 dilithium
  • HY-132144
    7-Deaza-7-propargylamino-dGTP

    		Biochemical Assay Reagents Others
    7-Deaza-7-propargylamino-dGTP is an analog of deoxyguanosine triphosphate (dGTP) that can be used for gene sequencing .
    7-Deaza-7-propargylamino-dGTP
  • HY-132140
    7-Deaza-7-propargylamino-3'-azidomethyl-dGTP

    		Biochemical Assay Reagents Others
    7-Deaza-7-propargylamino-3'-azidomethyl-dGTP is an analog of deoxyguanosine triphosphate (dGTP) that widely used in the next generation sequencing (NGS) .
    7-Deaza-7-propargylamino-3'-azidomethyl-dGTP
  • HY-W784575A
    dGTPαS sodium

    2'-deoxyguanosine-5'-O-(α-thio)triphosphate sodium

    		 Biochemical Assay Reagents DNA/RNA Synthesis Others
    dGTPαS sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
    dGTPαS sodium
  • HY-132140A
    7-Deaza-7-propargylamino-3'-azidomethyl-dGTP triethylamine

    		Biochemical Assay Reagents Others
    7-Deaza-7-propargylamino-3'-azidomethyl-dGTP triethylamine is an analog of deoxyguanosine triphosphate (dGTP) that widely used in the next generation sequencing (NGS) .
    7-Deaza-7-propargylamino-3'-azidomethyl-dGTP triethylamine
  • HY-175121
    3'-O-(5-Chloroanthraniloyl)-2'-deoxyguanosine-5'-O-triphosphate sodium

    		Fluorescent Dye Others
    3'-O-(5-Chloroanthraniloyl)-2'-deoxyguanosine-5'-O-triphosphate (sodium) is a fluorescent nucleotide triphosphate analog.
    3'-O-(5-Chloroanthraniloyl)-2'-deoxyguanosine-5'-O-triphosphate sodium
  • HY-W784575
    dGTPαS

    2'-deoxyguanosine-5'-O-(α-thio)triphosphate

    		 Nucleoside Antimetabolite/Analog Metabolic Disease
    dGTPαS (2'-Deoxyguanosine-5'-O-(α-thio)triphosphate) is a monomeric raw material that can be used for nucleic acid synthesis.
    dGTPαS
  • HY-132144A
    7-Deaza-7-propargylamino-dGTP sodium

    		Biochemical Assay Reagents Others
    7-Deaza-7-propargylamino-dGTP sodium is the sodium salt form of 7-Deaza-7-propargylamino-dGTP (HY-132144). 7-Deaza-7-propargylamino-dGTP sodium is an analog of deoxyguanosine triphosphate dGTP (HY-W008661) and can be used for gene sequencing .
    7-Deaza-7-propargylamino-dGTP sodium
  • HY-176826
    3'-Bromo ANT-dGTP sodium salt

    3'-O-(5-Bromoanthraniloyl)-2'-deoxyguanosine-5'-O-triphosphate sodium salt

    		 Nucleoside Antimetabolite/Analog Others
    3'-Bromo ANT-dGTP (3'-O-(5-Bromoanthraniloyl)-2'-deoxyguanosine-5'-O-triphosphate) sodium is a derivative of dGTP (HY-138616) .
    3'-Bromo ANT-dGTP sodium salt
  • HY-131805A
    3'-O-Ac-dGTP sodium

    		Drug Derivative Metabolic Disease
    3'-O-Ac-dGTP sodium is an acetylated derivative of the nucleoside triphosphate 2'-deoxyguanosine-5'-triphosphate .
    3'-O-Ac-dGTP sodium
  • HY-112817A
    8-Oxo-dGTP trisodium solution (100 mM)

    8-Oxo-deoxyguanosine triphosphate trisodium

    		 Apoptosis Others
    8-Oxo-dGTP (8-Oxo-Deoxyguanosine triphosphate) trisodium solution (100mM) is an oxidized guanine nucleotide formed by ROS-mediated oxidative modification of dGTP, and it also serves as a key substrate for 8-oxo-dGTP pyrophosphohydrolases (such as hMTH1 and E. coli MutT). 8-Oxo-dGTP trisodium solution (100mM) acts as a DNA mutagen, inserts into nascent DNA and pairs with adenine and cytosine, inducing A:T to C:G transversion mutations. Furthermore, 8-Oxo-dGTP trisodium solution (100mM) causes oxidative DNA base modification, strand breakage and S-phase arrest, and ultimately triggers AIF-mediated apoptosis and promotes spontaneous carcinogenesis in mth1-deficient mice. Accumulation of 8-Oxo-dGTP trisodium solution (100mM) in cells induces genomic instability, but it exhibits a tumor-suppressive effect that reduces tumor incidence in mouse models instead. 8-Oxo-dGTP trisodium solution (100mM) is widely used in studies related to spontaneous carcinogenesis, Parkinson's disease, Alzheimer's disease, heart failure and tumor mechanisms .
    8-Oxo-dGTP trisodium solution (100 mM)
  • HY-D3310
    Fluorescein-12-dGTP

    		Fluorescent Dye Others
    Fluorescein-12-dGTP is a fluorescein-labeled deoxyguanosine triphosphate. Fluorescein-12-dGTP incorporates into complementary allele-specific primers at SNP sites, enabling FRET with cationic conjugated polymer PFP via DNA-PFP electrostatic interactions. Fluorescein-12-dGTP incorporates into G-allele-specific primers for homozygous G/G SNP genotypes to enable genotype discrimination. Fluorescein-12-dGTP serves as a fluorescently labeled nucleotide for homogeneous solution-based SNP and FRET genotyping assays (Ex/Em = 498/517 nm) .
    Fluorescein-12-dGTP
  • HY-W013159R
    2'-Deoxyguanosine 5'-monophosphate disodium (Standard)

    5′-dGMP disodium (Standard)

    		 Endogenous Metabolite Reference Standards Nucleoside Antimetabolite/Analog Metabolic Disease
    2'-Deoxyguanosine 5'-monophosphate (disodium) (Standard) is the analytical standard of 2'-Deoxyguanosine 5'-monophosphate (disodium) (HY-W013159). This product is intended for research and analytical applications. 2'-Deoxyguanosine 5'-monophosphate (5′-dGMP) disodium is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a reactant involved in analysis of self-assembling in solution and nucleation/growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. 2'-Deoxyguanosine 5'-monophosphate disodium can be used as an oxidizable target. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative and is a nucleotide precursor used in DNA synthesis .
    2'-Deoxyguanosine 5'-monophosphate disodium (Standard)

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