Acyclovir triphosphate sodium (100 mM)
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Acyclovir triphosphate (Synonyms: AcycloGTP) sodium is a Acyclovir (HY-17422) derivative that competitively inhibits viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). Acyclovir triphosphate (sodium) (100 mM) is an inhibitor of HIV-1 reverse transcriptase. Acyclovir triphosphate (sodium) (100 mM) causes termination of viral DNA synthesis.
The product specifications provided below refer solely to the active content of Acyclovir triphosphate sodium.
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- Pureté : 99.61%
- CAS No.: 221119-43-3
- Formule: C8H14N5O12P3.xNa
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Stockage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Activité biologique
Description
The product specifications provided below refer solely to the active content of Acyclovir triphosphate sodium.
IC50 & Target
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DNA Polymerase |
Chemical Information
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CAS No. 221119-43-3
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Appearance Liquid
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Formule C8H14N5O12P3.xNa
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Color Colorless to light yellow
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SMILES
O=P(OP(OP(OCCOCN1C(N=C(N)NC2=O)=C2N=C1)(O)=O)(O)=O)(O)O.[x].[Na]
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Synonyms
AcycloGTP sodium (100 mM)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Pureté et documentation
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Fiche technique (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Hirsch MS, et al. Drug therapy: antiviral agents (second of two parts). N Engl J Med. 1980 Apr 24;302(17):949-53. [Content Brief]
[2]. McMahon MA,et al. Consistent inhibition of HIV-1 replication in CD4+ T cells by acyclovir without detection of human herpesviruses. J Virol. 2011 May;85(9):4618-22. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)