264 Results for "

eukaryotic

" in MedChemExpress (MCE) Product Catalog:
Products (264)

264 Results for "eukaryotic" in MCE Product Catalog:

68
68 Publications Verification
Cat. No.: HY-17561
CAS No.: 108321-42-2
Synonyms: Geneticin sulfate; Antibiotic G-418 sulfate
G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells .
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68
68 Publications Verification
Cat. No.: HY-108718
CAS No.: 49863-47-0
Synonyms: Geneticin; Antibiotic G-418
Research Areas:  

Infection

G-418 (Geneticin) is an aminoglycoside antibiotic with a structure similar to gentamicin. It is toxic to both eukaryotic and prokaryotic cells and works by interfering with protein synthesis .
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53
53 Cited Publications
Cat. No.: HY-13251
CAS No.: 697235-38-4
Purity:  99.96%
Synonyms: (-)-Silvestrol
Silvestrol is a eukaryotic translation initiation factor 4A (eIF4A) inhibitor isolated from Agave americana Linn.. Silvestrol induces autophagy and caspase-mediated apoptosis .
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41
41 Cited Publications
Cat. No.: HY-K1014

MCE PolyFast Transfection Reagent consists of cationic polymers and can introduce nucleic acids (DNA or RNA) into eukaryotic cells efficiently, including some hard-to-transfect cells.

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38
38 Cited Publications
Cat. No.: HY-B0490
CAS No.: 31282-04-9
Synonyms: Hygrovetine
Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.
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38
38 Cited Publications
Cat. No.: HY-10529
CAS No.: 472-15-1
Purity:  99.06%
Synonyms: Lupatic acid; Betulic acid
Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties . Betulinic acid can cross the blood-brain barrier .
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25
25 Cited Publications
Cat. No.: HY-16909
CAS No.: 87081-35-4
Synonyms: CI 940; LMB
Target:  

CRM1 Fungal Antibiotic

Research Areas:  

Infection Cancer

Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle .
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12
12 Cited Publications
Cat. No.: HY-B2233B
CAS No.: 3616-04-4
Synonyms: Phosphocholine
Phosphatidylcholine is the main phospholipid component in eukaryotic biofilms. Phosphatidylcholine exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine exhibits a surprising range of immunomodulatory properties .
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12
12 Cited Publications
Cat. No.: HY-B2233
CAS No.: 107-73-3
Synonyms: Phosphocholine chloride
Phosphorylcholine chloride (Phosphocholine chloride) is the main phospholipid component in eukaryotic biofilms. Phosphorylcholine chloride exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine chloride exhibits a surprising range of immunomodulatory properties .
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12
12 Cited Publications
Cat. No.: HY-B2233A
CAS No.: 4826-71-5
Calcium phosphorylcholine chloride, 98% is the main phospholipid component in eukaryotic biofilms. Calcium phosphorylcholine chloride, 98% exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Calcium phosphorylcholine chloride, 98% exhibits a surprising range of immunomodulatory properties .
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9
9 Cited Publications
Cat. No.: HY-110096
CAS No.: 142557-61-7
Purity:  99.34%
Target:  

CaMK Autophagy

Research Areas:  

Cancer

A-484954 is a highly selective eukaryotic elongationfactor-2 kinase(eEF2K) inhibitor, with an IC50 of 280 nM.
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8
8 Cited Publications
Cat. No.: HY-K1056

MCE G418 Selective Antibiotic, Sterile (50 mg/mL) is an aminoglycoside antibiotic produced by Micromonospora rhodorangea. It acts by binding to the 80S subunit of the bacterial ribosome, thus inhibiting protein synthesis in both prokaryotic and eukaryotic cells.

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6
6 Cited Publications
Cat. No.: HY-100875
CAS No.: 78186-34-2
Purity:  98.08%
Synonyms: CL216942
Target:  

Topoisomerase

Research Areas:  

Cancer

Bisantrene is a highly effective antitumor agent, it exerts its cytotoxicity by affecting DNA intercalation. Bisantrene targets eukaryotic type II topoisomerases. Bisantrene is a substrate of MDR1 .
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6
6 Cited Publications
Cat. No.: HY-100875A
CAS No.: 71439-68-4
Purity:  98.86%
Synonyms: CL-216942 dihydrochloride
Target:  

Topoisomerase

Research Areas:  

Cancer

Bisantrene dihydrochloride is a highly effective antitumor agent, it exerts its cytotoxicity by affecting DNA intercalation. Bisantrene dihydrochloride targets eukaryotic type II topoisomerases. Bisantrene dihydrochloride is a substrate of MDR1 .
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5
5 Cited Publications
Cat. No.: HY-D0098
CAS No.: 75350-46-8
Synonyms: N-(5-Fluoresceinyl)maleimide
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
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4
4 Cited Publications
Cat. No.: HY-15969
CAS No.: 1164470-53-4
Target:  

Phosphatase Apoptosis

Research Areas:  

Cancer

Sal003 is a potent, specific and cell-permeable inhibitor of the eukaryotic translation initiation factor 2α (eIF2α) phosphatase. Sal003 is a derivative of salubrinal .
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4
4 Cited Publications
Cat. No.: HY-125021
CAS No.: 2143542-28-1
Purity:  99.31%
2BAct is a highly selective, orally active, and CNS-penetrant eIF2B (eukaryotic initiation factor 2B) activator with an EC50 of 33 nM. 2BAct prevents neurological defects caused by a chronic integrated stress response. 2BAct displays improved solubility and pharmacokinetics relative to eIF2B activator ISRIB trans-isomer (HY-12495) .
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4
4 Cited Publications
Cat. No.: HY-P80811
Synonyms: EIF2S1; EIF2A; eukaryotic translation initiation factor 2 subunit 1; eukaryotic translation initiation factor 2 subunit alpha; eIF-2-alpha; eIF-2A; eIF-2alpha

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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4
4 Cited Publications
Cat. No.: HY-113137
CAS No.: 2140-67-2
Purity:  99.40%
N2,N2-Dimethylguanosine is a methylated modified nucleoside present in RNA and serves as a structural modification component of tRNA. N2,N2-Dimethylguanosine inhibits reverse transcriptase-mediated cDNA synthesis and is one of the key modifications affecting sequencing efficiency in high-throughput RNA sequencing. N2,N2-Dimethylguanosine can be selectively demethylated at one methyl group by AlkB mutant enzymes (such as D135S/L118V) and converted to N2-methylguanosine, thereby reducing the inhibition of reverse transcription .
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3
3 Cited Publications
Cat. No.: HY-12801
CAS No.: 1337883-32-5
Purity:  99.85%
Research Areas:  

Others

DiZPK is a photocrosslinker for identifying direct protein-protein interactions in living prokaryotic and eukaryotic cells.
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