24 Results for "

glycoprotein IIb/IIIa receptor

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "glycoprotein IIb/IIIa receptor" in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-B0686
CAS No.: 188627-80-7
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Eptifibatide is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
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9
9 Publications Verification
Cat. No.: HY-B0686B
CAS No.: 881997-86-0
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
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3
3 Cited Publications
Cat. No.: HY-P0074
CAS No.: 67869-62-9
Synonyms: Gly-Pro-Arg-Pro; Pefa 6003
Target:  

Thrombin

Research Areas:  

Cardiovascular Disease

GPRP (Gly-Pro-Arg-Pro; Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction between fibrinogen and the platelet membrane glycoprotein Ⅱb/IIIa complex (glycoprotein IIb/IIIa receptor) . GPRP increases the level of free thrombin in activated platelet-rich plasma by reducing the adsorption of thrombin onto fibrin. GPRP inhibits platelet aggregation and prolongs the thrombin-initiated clotting time in plasma. GPRP is applicable for research related to thrombosis and thrombotic diseases .
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2
2 Cited Publications
Cat. No.: HY-P9934
CAS No.: 143653-53-6
Synonyms: C7E3

Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Abciximab (C7E3), a chimeric mouse/human monoclonal antibody fragment, is a glycoprotein (GP) IIb/IIIa inhibitor. Abciximab inhibits platelet aggregation and leucocyte adhesion by binding to the glycoprotein IIb/IIIa, vitronectin and Mac-1 receptors .
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Cat. No.: HY-B0686A
CAS No.: 1248559-53-6
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Eptifibatide monoacetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
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Cat. No.: HY-10308
CAS No.: 149503-79-7
Target:  

Integrin

Research Areas:  

Metabolic Disease

Lefradafiban is an orally active glycoprotein IIb/IIIa receptor antagonist. Lefradafiban can be metabolized to its active form, Fradafiban, a non-peptide GP IIb/IIIa receptor antagonist .
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Cat. No.: HY-10307
CAS No.: 170902-47-3
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Roxifiban is a platelet glycoprotein (GP) IIb/IIIa receptor inhibitor that can be used in the study of angina .
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Cat. No.: HY-10313
CAS No.: 185836-64-0
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

ZD 2486 is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist. ZD 2486 inhibits platelet aggregation by blocking the binding of fibrinogen to the GP IIb/IIIa receptor on platelets. ZD 2486 can be used for the study of conditions related to unwanted platelet aggregation, such as acute coronary syndrome, unstable angina pectoris, acute myocardial infarction, and complications from cardiovascular interventional procedures [1]
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Cat. No.: HY-10307A
CAS No.: 176022-59-6
Synonyms: DMP 754
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Roxifiban (acetate) is the acetate form of Roxifiban (HY-10307). Roxifiban (acetate) is a platelet glycoprotein (GP) IIb/IIIa receptor inhibitor that can be used in research related to angina .
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Cat. No.: HY-10309
CAS No.: 172927-65-0
Purity:  99.67%
Synonyms: RO 48-3657
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Sibrafiban (RO 48-3657) is the orally active, nonpeptide, double-proagent of Ro 44-3888 and a selective glycoprotein IIb/IIIa receptor antagonist. Sibrafiban inhibits platelet aggregation .
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Cat. No.: HY-111348
CAS No.: 144412-49-7
Synonyms: Ro 44-9883
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Lamifiban is a nonpeptide glycoprotein IIb/IIIa receptor and platelet aggregation antagonist. Lamifiban in combination with thrombolytic therapy effectively restores coronary arterial patency. Lamifiban is promising for research of acute coronary syndromes .
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Cat. No.: HY-108881R
CAS No.: 2751-09-9
Synonyms: Triacetyloleandomycin (Standard)
Eptifibatide (acetate) (Standard) is the analytical standard of Eptifibatide (acetate). This product is intended for research and analytical applications. Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
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Cat. No.: HY-B0686BR
CAS No.: 881997-86-0
Research Areas:  

Cardiovascular Disease

Eptifibatide (acetate) (Standard) is the analytical standard of Eptifibatide (acetate). This product is intended for research and analytical applications. Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .
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Cat. No.: HY-111348A
CAS No.: 144412-50-0
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Lamifiban TFA is a nonpeptide glycoprotein IIb/IIIa receptor and platelet aggregation antagonist. Lamifiban TFA in combination with thrombolytic therapy effectively restores coronary arterial patency. Lamifiban TFA is promising for research of acute coronary syndromes .
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Cat. No.: HY-125615
CAS No.: 155158-97-7
Target:  

Glycoprotein VI

Research Areas:  

Cardiovascular Disease Others

DMP 728 methanesulfonate is a platelet glycoprotein (GP) IIb/IIIa receptor antagonist. DMP 728 methanesulfonate shows dose-dependent antiplatelet and antithrombotic effects. DMP 728 methanesulfonate can be used in the study of effective antithrombotic agents in thromboembolic diseases of coronary and peripheral arteries .
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Cat. No.: HY-10309R
CAS No.: 172927-65-0
Synonyms: RO 48-3657 (Standard)
Research Areas:  

Cardiovascular Disease

Sibrafiban (Standard) is the analytical standard of Sibrafiban. This product is intended for research and analytical applications. Sibrafiban (RO 48-3657) is the orally active, nonpeptide, double-proagent of Ro 44-3888 and a selective glycoprotein IIb/IIIa receptor antagonist. Sibrafiban inhibits platelet aggregation .
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Cat. No.: HY-167686
CAS No.: 3187-52-8
Synonyms: Homopisatin
Variabilin (Homopisatin) is a potent RGD-containing antagonist of glycoprotein IIb-IIIa and platelet aggregation inhibitor from the hard tick Dermacentor variabilis. Variabilin potently inhibits platelet aggregation induced by the platelet agonists ADP, collagen, and thrombin receptor peptide SFLLRNP. Variabilin also blocks platelet adhesion to immobilized Fg. In addition, Variabilin inhibits binding of purified human GPIIb-IIIa to immobilized Fg .
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Cat. No.: HY-P3082
CAS No.: 126053-71-2
Target:  

Endogenous Metabolite

Research Areas:  

Cardiovascular Disease

SKF 106760 is a potent platelet fibrin receptor (glycoprotein IIb/IIIa) antagonist with significant antiplatelet and antithrombotic activities. SKF 106760 inhibits platelet aggregation in dogs in vitro and prevents thrombus formation in stenotic carotid arteries. SKF 106760 has also shown elimination effects against aspirin-resistant thrombi that develop in the setting of high-grade stenosis .
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Cat. No.: HY-106394
CAS No.: 138297-15-1
Target:  

P-glycoprotein

Research Areas:  

Cardiovascular Disease

TP-9201 is a platelet glycoprotein (GP) IIb/IIIa receptor antagonist. TP-9201 inhibits the interaction between GPIIb/IIIa and fibrinogen, thereby suppressing platelet aggregation. TP-9201 exhibits similar inhibitory activity on adenosine diphosphate (ADP) (HY-W010918)-induced platelet aggregation in humans, baboons, and dogs (IC50 = 1-3 μM), while showing lower activity in rabbits (IC50 = 45 μM) and rats (IC50 = 20 μM). TP-9201can be used in studies related to the prevention of rethrombosis after arterial thrombolysis .
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Cat. No.: HY-125668
CAS No.: 138107-58-1
Target:  

Integrin

Research Areas:  

Cancer

Ro 43-5054 is a platelet glycoprotein IIb-IIIa receptor antagonist. Ro 43-5054 can be used in the research of early reocclusion after thrombolytic therapy .
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