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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
167 Results for "
glycosylation
" in MedChemExpress (MCE) Product Catalog:
Products (167)
167 Results for "glycosylation" in MCE Product Catalog:
180
180 Publications Verification
Cat. No.: HY-A0098
CAS No.: 11089-65-9
13
Target:
Research Areas:
Benzyl-α-GalNAc is a potent O-glycosylation inhibitor. Benzyl-α-GalNAc effectively inhibits the proliferation and activation of LX-2 cells and suppresses the expression of collagen I/III, which has good potential for investigation in liver fibrosis. Benzyl-α-GalNAc also significantly enhances the anti-tumour activity of 5-Fluorouracil (HY-90006) (e.g. pancreatic cancer) by inhibiting O-glycosylation .
10
10 Cited Publications
Cat. No.: HY-P7387
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MIF; L-Dopachrome Isomerase; Prev. GLIF; glycosylation-Inhibiting Factor; Phenylpyruvate Tautomerase; MMIF; GIF; Epididymis Secretory Sperm Binding Protein; L-Dopachrome Tautomerase; Macrophage Migration Inhibitory Factor; Macrophage Migration Inhibitory
Species:
Human
Source:
E. coli
3
3 Cited Publications
Cat. No.: HY-W013707
CAS No.: 81012-87-5
Synonyms: Cytidine triphosphate disodium dihydrate; 5'-CTP disodium dihydrate
Target:
Research Areas:
Cytidine-5'-triphosphate disodium dihydrate (5'-CTP disodium dihydrate) is a molecule of high energy, and acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation .
3
3 Cited Publications
Cat. No.: HY-P7388
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MIF; L-Dopachrome Isomerase; Prev. GLIF; glycosylation-Inhibiting Factor; Phenylpyruvate Tautomerase; MMIF; GIF; Epididymis Secretory Sperm Binding Protein; L-Dopachrome Tautomerase; Macrophage Migration Inhibitory Factor; Macrophage Migration Inhibitory
Species:
Mouse
Source:
E. coli
3
Category:
Flavonoids Monophenols Flavones Labiatae Phenols Plants Disease Research Fields Medicago truncatula Gaertn. Inflammation/Immunology
Target:
2
2 Cited Publications
Cat. No.: HY-160109
Target:
Research Areas:
Ac5GalNTGc is a potent, peracetylated C-2 thioglycolyl-substituted GalNAc analog that efficiently inhibits mucin-type O-glycan biosynthesis. Ac5GalNTGc reduces leukocyte sialyl-Lewis-X expression and inhibits L-/P-selectin mediated rolling under flow, as well as P-selectin dependent leukocyte-platelet adhesion. Ac5GalNTGc exhibits anti-inflammatory activity in a thioglycollate-induced acute peritonitis model. Ac5GalNTGc can be used for studies of O-glycan/mucin biology, inflammation, and related translational research .
2
2 Cited Publications
Cat. No.: HY-P7467
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AGER; Receptor For Advanced glycosylation End-Products Deletion Exon3-10 Variant; Advanced glycosylation End-Product Specific Receptor; Receptor For Advanced glycosylation End-Products Deletion Exon2-6 Variant; RAGE; Advanced glycosylation End Product-Spe
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-W009783
CAS No.: 73465-43-7
Target:
1
1 Cited Publications
Synonyms: 3,3',4',5',7-Pentahydroxyflavone
Category:
Infection Flavonols other families Flavonoids Phenols Polyphenols Plants Disease Research Fields
Target:
1
1 Cited Publications
1
1 Cited Publications
Category:
Target:
1
1 Cited Publications
Research Areas:
ML089 is an orally active inhibitor of phosphomannose isomerase (PMI) and PHOSPHO1, with an IC50 value of 1.3 μM against human PMI and an IC50 value of 0.8 μM against PHOSPHO1. ML089 blocks the catabolism of mannose-6-phosphate, directs mannose-6-phosphate to participate in protein glycosylation, increases mannose incorporation into cellular proteins, and reduces tritiated water production from mannose-6-phosphate. ML089 inhibits PMI in living cells. ML089 can be used in research related to congenital disorder of glycosylation type Ia (CDG-Ia) .
1
1 Cited Publications
Cat. No.: HY-113230B
Purity: 99.69%
Target:
1
1 Cited Publications
Cat. No.: HY-129099
CAS No.: 31750-48-8
Category:
Target:
1
1 Cited Publications
Cat. No.: HY-KE7057
O-Glycosidase is highly specific and can release Galβ1-3GalNAc from serine, threonine residues or as part of a glycopeptide or glycoprotein. Applied to glycoprotein biosynthesis analysis, O-glycan bioactive protein O-glycosylation detection and binding site analysis.
1
1
1 Cited Publications
Synonyms: UDP-N-acetyl-D-galactosamine disodium
Target:
1
Category:
Natural Products Arachis hypogaea L. Leguminosae Other Diseases Plants Disease Research Fields
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
