2. Search Result
Search Result
Isoforms Recommended: TRPC3
Results for "

hTRPC3

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101795
    Larixyl acetate
    2 Publications Verification

    		 TRP Channel HPV Autophagy Apoptosis PERK Akt Src Infection Cardiovascular Disease Neurological Disease
    Larixyl acetate is a potent and selective TRPC6 inhibitor with IC50 values of 0.58 μM and 6.83 μM against hTRPC6-YFP and hTRPC3-YFP, respectively. Larixyl acetate prevents HPV and is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction [3] .
    Larixyl acetate
  • HY-138668
    JW-65

    		TRP Channel Neurological Disease
    JW-65 is a selective TRPC3 channel inhibitor with favorable blood-brain barrier penetration. JW-65 directly binds to human TRPC3 protein and modulates calcium signaling to reduce seizure susceptibility. JW-65 reduces seizure incidence, severity, and duration while prolonging seizure latency in multiple seizure models. JW-65 alleviates Aβ‑induced neuronal damage. JW-65 serves as a valuable tool for research on epilepsy, seizure disorders, and Alzheimer’s disease [3].
    JW-65
  • HY-147357
    TRPC3/6-IN-1

    		TRP Channel Cardiovascular Disease
    TRPC3/6-IN-1 is a potent selectivity blocker of the canonical transient receptor channels (TRPC3/6), has block potency for hTRPC3 and hTRPC6 with IC50 values of 1260 nM and 500 nM, respectively. TRPC3/6-IN-1 can be used for the research of chronic models of heart failure .
    TRPC3/6-IN-1
  • HY-101795R
    Larixyl acetate (Standard)

    		Reference Standards TRP Channel HPV Infection Neurological Disease
    Larixyl acetate (Standard) is the analytical standard of Larixyl acetate. This product is intended for research and analytical applications. Larixyl acetate is a potent and selective TRPC6 inhibitor with IC50 values of 0.58 μM and 6.83 μM against hTRPC6-YFP and hTRPC3-YFP, respectively. Larixyl acetate prevents HPV and is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction .
    Larixyl acetate (Standard)
  • HY-185477
    TRPC3-IN-1

    		TRP Channel Neurological Disease
    TRPC3-IN-1 is a human transient receptor potential canonical 3 (hTRPC3) inhibitor with an IC50 of 0.09 μM. TRPC3-IN-1 inhibits hTRPC3-mediated currents. TRPC3-IN-1 is applicable to research related to diseases such as epilepsy .
    TRPC3-IN-1
  • HY-179489
    TRPC3 agonist-1

    		TRP Channel Others
    TRPC3 agonist-1 (compound 4n) is a selective and competitive TRPC3 channel agonist. TRPC3 agonist-1 binds at L2 site of hTRPC3 .
    TRPC3 agonist-1

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: