15 Results for "

hederagenin

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "hederagenin" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-N0256
CAS No.: 465-99-6
Hederagenin is a triterpenoid saponin with orally active and antitumor activity. Hederagenin can inhibit the expression of iNOS, COX-2, and NF-κB in cells induced by LPS stimulation. Hederagenin also increases ROS production in cancer cells, disrupts mitochondrial membrane potential, and induces apoptosis. Hederagenin also sensitizes cancer cells to Cisplatin (HY-17394) and Paclitaxel (HY-B0015), enhancing induced apoptosis. Hederagenin can also bind to SKP2, with KD = 67.9 μM. Hederagenin also has preventive potential against alcoholic liver injury .
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Cat. No.: HY-N0256R
CAS No.: 465-99-6
Hederagenin (Standard) is the analytical standard of Hederagenin. This product is intended for research and analytical applications. Hederagenin is a triterpenoid saponin with orally active and antitumor activity. Hederagenin can inhibit the expression of iNOS, COX-2, and NF-κB in cells induced by LPS stimulation. Hederagenin also increases ROS production in cancer cells, disrupts mitochondrial membrane potential, and induces apoptosis. Hederagenin also sensitizes cancer cells to Cisplatin (HY-17394) and Paclitaxel (HY-B0015), enhancing induced apoptosis. Hederagenin also has preventive potential against alcoholic liver injury .
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Cat. No.: HY-N12017
CAS No.: 128717-92-0
3-O-α-L-Rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin28-O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl ester is a hederagenin-type saponin with antitumor and anti-inflammatory properties .
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Cat. No.: HY-N2190
CAS No.: 53931-25-2
Hederagenin 28-O-beta-D-glucopyranosyl ester, a triterpenoid saponin isolated from Ilex cornuta, exhibits protective effects against H2O2-induced myocardial cell injury .
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Cat. No.: HY-144366
CAS No.: 2766451-11-8
Target:  

P-glycoprotein

Research Areas:  

Cancer

P-gp inhibitor 3 is an effective P-glycoprotein (P-gp) inhibitor. P-gp inhibitor 3 inhibits the efflux function of P-gp by activating P-gp ATPase. P-gp inhibitor 3 has relatively stronger multidrug resistance (MDR) reversal ability and enhances the anti-tumor activity of Paclitaxel .
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Cat. No.: HY-113327R
CAS No.: 5415-44-1
Hederagenin (Standard) is the analytical standard of Hederagenin. This product is intended for research and analytical applications. Hederagenin is a triterpenoid saponin with orally active and antitumor activity. Hederagenin can inhibit the expression of iNOS, COX-2, and NF-κB in cells induced by LPS stimulation. Hederagenin also increases ROS production in cancer cells, disrupts mitochondrial membrane potential, and induces apoptosis. Hederagenin also sensitizes cancer cells to Cisplatin (HY-17394) and Paclitaxel (HY-B0015), enhancing induced apoptosis. Hederagenin also has preventive potential against alcoholic liver injury .
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Cat. No.: HY-N8116
CAS No.: 20830-84-6
Leonloside D is a Hederagenin-derived saponin, composed of a molecule of Hederagenin and 1-3 molecules of rhamnose, glucose, or arabinose .
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Cat. No.: HY-N17985
CAS No.: 119742-55-1
Kalopanaxsaponin H is an hederagenin glycoside (saponin) with no hypoglycemic activity upon intraperitoneal injection. Kalopanaxsaponin H can be metabolized by human intestinal bacteria into Kalopanaxsaponin I, Kalopanaxsaponin A, hederagenin 3-O-α-L-arabinopyranoside and hederagenin, among which Kalopanaxsaponin I and hederagenin are the main metabolites. Kalopanaxsaponin H is isolated from the stem bark of Kalopanax pictus and is used in diabetes-related research .
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Cat. No.: HY-N18269
CAS No.: 639515-41-6
3-O-α-L-Arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl ester is an anti-fungal triterpene saponin. 3-O-α-L-Arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl ester can be isolated from the aerial parts of Clematis tangutica. 3-O-α-L-Arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl ester exhibits antifungal activity against fungal strains (P. avellaneum, C. glabrata, S. cerevisiae, T. beigelii), with the strongest activity against S. cerevisiae .
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Cat. No.: HY-N18022
CAS No.: 1588441-61-5
Septemloside D (Compound 5) is a hederagenin triterpene saponin found in Kalopanacis Cortex .
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Cat. No.: HY-N21541
CAS No.: 178825-03-1
Pulsatiloside B is a triterpenoid saponin present in the roots of Pulsatilla campanella. Pulsatilosides B exerts an inhibitory effect on the motility of human sperm in vitro .
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Cat. No.: HY-N17877
CAS No.: 155740-20-8
Loniceroside A is a triterpenoid saponin found in the aerial parts of Lonicera japonica .
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Cat. No.: HY-N20722
CAS No.: 57539-70-5
Synonyms: Cussonoside A
Pulsatiloside C (Cussonoside A) is an orally active triterpenoid saponin. Pulsatiloside C can be isolated from the roots of Pulsatilla campanella and the stem bark of Cussonia barteri. Pulsatiloside C exhibits sedative activity. Pulsatiloside C reduces locomotor activity in male Swiss albino mice. Pulsatiloside C shows no molluscicidal activity against Biomphalaria glabrata .
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Cat. No.: HY-N18021
CAS No.: 102719-83-5
3-O-[α-L-Arabinopyranosyl]-30-norolean-12,20(29)-dien-28-oic acid (Compound 1) is a triterpenoid glucoside found in Stauntonia brachyanthera Hand-Mazz .
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Cat. No.: HY-N19715
CAS No.: 159993-47-2
Asperosaponin H1 is a triterpenoid saponin (octasaccharide saponin) found in the roots of Dipsacus asperoides C.Y. Cheng et T.M. Ai. Asperosaponin H1 can be used for research on liver and kidney diseases .
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