5415-44-1
5415-44-1
Chemical Structure
1,3,7-Trimethyluric acid
- CAS No.: 5415-44-1
- Formula:C8H10N4O3
- Molecular Weight:210.19
IUPAC Name: 1,3,7-trimethyl-7,9-dihydro-1H-purine-2,6,8(3H)-trione
InChIKey: BYXCFUMGEBZDDI-UHFFFAOYSA-N
SMILES: O=C(N1C)N(C)C2=C(N(C)C(N2)=O)C1=O
Biological Activity: 1,3,7-Trimethyluric acid is the metabolite of caffeine. The metabolic ratio 1,3,7-Trimethyluric acid to caffeine can be evaluated as a biomarker to describe variability in CYP3A activity in a cohort[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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1,3,7-Trimethyluric acid | 99.99% | 1,3,7-Trimethyluric acid is the metabolite of caffeine. The metabolic ratio 1,3,7-Trimethyluric acid to caffeine can be evaluated as a biomarker to describe variability in CYP3A activity in a cohort. | ||||||||||||||||||||
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1,3,7-Trimethyluric acid (Standard) | ≥98% | Hederagenin (Standard) is the analytical standard of Hederagenin. This product is intended for research and analytical applications. Hederagenin is a triterpenoid saponin with orally active and antitumor activity. Hederagenin can inhibit the expression of iNOS, COX-2, and NF-κB in cells induced by LPS stimulation. Hederagenin also increases ROS production in cancer cells, disrupts mitochondrial membrane potential, and induces apoptosis. Hederagenin also sensitizes cancer cells to Cisplatin (HY-17394) and Paclitaxel (HY-B0015), enhancing induced apoptosis. Hederagenin also has preventive potential against alcoholic liver injury. | ||||||||||||||||||||
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1,3,7-Trimethyluric acid-d9 | 1,3,7-Trimethyluric acid-d9 is the deuterium labeled 1,3,7-Trimethyluric acid. | |||||||||||||||||||||
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1,3,7-Trimethyluric acid-13C4,15N3 | 1,3,7-Trimethyluric acid-13C4,15N3 is the 13C and 15N labeled 1,3,7-Trimethyluric acid. 1,3,7-Trimethyluric acid is the metabolite of caffeine. The metabolic ratio 1,3,7-Trimethyluric acid to caffeine can be evaluated as a biomarker to describe variability in CYP3A activity in a cohort. | |||||||||||||||||||||
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References
