57539-70-5
Chemical Structure
Pulsatiloside C
Synonym(s): Cussonoside A
- CAS No.: 57539-70-5
- Formula:C48H78O18
- Molecular Weight:943.13
IUPAC Name: (2S,3R,4S,5S,6R)-6-((((2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl (4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-10-hydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylate
InChIKey: YGSBJLPWANWGED-HYXYOFMCSA-N
SMILES: C(O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)(=O)[C@]45[C@](C=6[C@@](C)(CC4)[C@@]7(C)[C@](CC6)([C@]8(C)[C@@](CC7)([C@@](CO)(C)[C@@H](O)CC8)[H])[H])(CC(C)(C)CC5)[H]
Biological Activity: Pulsatiloside C (Cussonoside A) is an orally active triterpenoid saponin. Pulsatiloside C can be isolated from the roots of Pulsatilla campanella and the stem bark of Cussonia barteri. Pulsatiloside C exhibits sedative activity. Pulsatiloside C reduces locomotor activity in male Swiss albino mice. Pulsatiloside C shows no molluscicidal activity against Biomphalaria glabrata[1][2][3].
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Pulsatiloside C | Pulsatiloside C (Cussonoside A) is an orally active triterpenoid saponin. Pulsatiloside C can be isolated from the roots of Pulsatilla campanella and the stem bark of Cussonia barteri. Pulsatiloside C exhibits sedative activity. Pulsatiloside C reduces locomotor activity in male Swiss albino mice. Pulsatiloside C shows no molluscicidal activity against Biomphalaria glabrata. | |||||||||||||||||||||
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References
- [1]. Li X C, et al. Triterpenoid saponins from Pulsatilla campanella[J]. Phytochemistry, 1990, 29(2): 595-599.
- [2]. Dubois MA, et al. Cussonosides A and B, two triterpene-saponins from Cussonia barteri. Planta Med. 1986 Apr;(2):80-3. PMID: 3725939.
- [3]. Igbe I, et al. Harnessing the medicinal properties of Cussonia barteri Seem.(Araliaceae) in drug development. A review[J]. Herba Polonica, 2018, 64(3).
