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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
human saphenous vein
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "human saphenous vein" in MCE Product Catalog:
1
Cat. No.: HY-P3433
CAS No.: 120972-53-4
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Cat. No.: HY-103459
CAS No.: 162256-50-0
Synonyms: PD156707
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CI-1020 (PD156707) is an orally active and selective antagonist targeting endothelin (ETA) with an IC50 value of 0.3 nM. CI-1020 blocks intimal hyperplasia in human saphenous veins completely in organ culture. CI 1020 inhibits hypoxic pulmonary hypertension and blocks ET-1-induced pressor responses following oral administration .
Cat. No.: HY-19138
CAS No.: 135809-60-8
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SR 47063 is an ATP-sensitive potassium channel (KATP) agonist. SR 47063 selectively activates KATP channels in vascular smooth muscle cells (IC50: 8.1 nM in human saphenous vein, 3.86 nM in rat aorta). SR 47063 promotes potassium efflux and cellular hyperpolarization to induce vasorelaxation. SR 4706 is promising for research of hypertension and related cardiovascular disorders .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
