SR 47063
SR 47063 is an ATP-sensitive potassium channel (KATP) agonist. SR 47063 selectively activates KATP channels in vascular smooth muscle cells (IC50: 8.1 nM in human saphenous vein, 3.86 nM in rat aorta). SR 47063 promotes potassium efflux and cellular hyperpolarization to induce vasorelaxation. SR 4706 is promising for research of hypertension and related cardiovascular disorders.
For research use only. We do not sell to patients.
- CAS No.: 135809-60-8
- Formula: C17H14N4O3
- Molecular Weight:322.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 135809-60-8
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Molecular Weight 322.32
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Formula C17H14N4O3
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SMILES
N#C/N=C1C=CC=CN\1C2=CC(C)(C)OC3=C2C=C([N+]([O-])=O)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)