Search Result

Results for "

hydroxyl groups

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1) ADC Linker (2) Amino Acid Derivatives (1) Amyloid-β (1) Antibiotic (3) Apoptosis (3) Bacterial (3) Biochemical Assay Reagents (180) c-Myc (1) Ceramidase (1) Complement System (1) DNA/RNA Synthesis (8) Drug Derivative (7) Drug Intermediate (8) Drug Isomer (3) Drug Metabolite (10) Endogenous Metabolite (16) Environmental Pollutants (5) Fluorescent Dye (15) Fungal (1) Glycosidase (1) HCV (2) HIV (5) HIV Protease (4) Isotope-Labeled Compounds (2) Lipase (3) Liposome (2) Microtubule/Tubulin (1) Mitochondrial Metabolism (1) MOFs (1) Na+/K+ ATPase (1) NO Synthase (1) Nucleoside Antimetabolite/Analog (5) Parasite (1) PDI (1) Phosphatase (2) Pim (1) PKC (1) Prostaglandin Receptor (1) PROTAC Linkers (1) PROTACs (1) Reactive Oxygen Species (ROS) (2) Reference Standards (11) SGK (1) SULT (1) TNF Receptor (1) Tyrosinase (2) UGT (1) VD/VDR (2) Xanthine Oxidase (1)
By Research Areas:	Cancer (22) Cardiovascular Disease (4) Endocrinology (4) Infection (12) Inflammation/Immunology (9) Metabolic Disease (12) Neurological Disease (4)
Click Chemistry:	Labeling and Fluorescence Imaging (1) DBCO (8) Azide (5)
Oligonucleotides:	Nucleoside Analogs (1) Nucleotide Analogs (3) Inosine (1) Cationic Lipids (1) Polymers (2) Cytidine Nucleotide (1)

275

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

133

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-103006

NAI-N3 5 Publications Verification	Biochemical Assay Reagents	Others
NAI-N3 is a RNA acylation reagent that enables RNA purification. NAI-N3 is a dual-function SHAPE (selective 2-hydroxyl acylation and profiling experiment) probe (RNA structure probe and enrichment) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-Y0850E

Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) 3 Publications Verification PVA (Mw 30000-70000, 87-90% hydrolyzed); Poly(Ethenol) (Mw 30000-70000, 87-90% hydrolyzed)	Environmental Pollutants Biochemical Assay Reagents	Cardiovascular Disease Cancer
Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 30000-70000 and hydrolytic properties. The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process. Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. A degree of hydrolysis of 87-90% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipients .

HY-79880

N,N'-Carbonyldiimidazole 1,1'-Carbonyldiimidazole	MOFs	Others
N,N'-Carbonyldiimidazole (1,1'-Carbonyldiimidazole) is a highly reactive carboxylating reagent that can activate hydroxyl groups to form reactive carbonyl groups. N,N'-Carbonyldiimidazole can be used as a coupling agent and a peptide synthesis reagent .

HY-126994

6′-Amino-D-luciferin	Fluorescent Dye	Others
6’-Amino-D-luciferin is a derivative of D-luciferin (HY-12591A) with an amino group replacing the 6-hydroxyl group. 6’-Amino-D-luciferin is a natural substrate of luciferase (Luc) and can be used for IVIS imaging in cell/animal experiments[1][2][3].

HY-Y0850M

Polyvinyl alcohol (Mw 85000-124000, 87-89% hydrolyzed) 3 Publications Verification PVA (Mw 85000-124000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 85000-124000, 87-89% hydrolyzed)	Environmental Pollutants Biochemical Assay Reagents	Others
Polyvinyl alcohol (Mw 85000-124000, 87-89% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 85000-124000 and hydrolytic properties. The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process. Polyvinyl alcohol (Mw 85000-124000, 87-89% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. A degree of hydrolysis of 87-89% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipient .

HY-134222A

N-Acetylserine N-Acetyl-L-serine	Endogenous Metabolite Complement System	Others
N-Acetylserine (N-Acetyl-L-serine) is a complement pathway modulator targeting activated third complement protein (C3b) and an amino-terminal residue (an N-terminal acetylation modification group). N-Acetylserine reacts with the exposed thioester group of C3b via its hydroxyl group, thereby blocking the covalent binding of glycerol to this thioester group. N-Acetylserine widely exists in soluble proteins of mammalian cells (accounting for approximately 80% of such proteins). N-Acetylserine has a blocking property that prevents direct Edman sequencing of proteins; deblocking is achievable through trifluoroacetic acid-catalyzed N→O acetyl migration followed by β-elimination. N-Acetylserine is suitable for sequencing of proteins with N-terminal acetylserine modification .

HY-N2436

2,3-Dihydroxysuccinic acid Tartaric acid	Biochemical Assay Reagents	Others
2,3-Dihydroxysuccinic acid (Tartaric acid) is an organic acid containing two hydroxyl groups and two carboxyl groups. 2,3-Dihydroxysuccinic acid exists in various stereoisomers and is widely used in food, pharmaceutical, chemical, and other fields .

HY-Y0801

2,6-Dihydroxybenzoic acid	Drug Metabolite	Others
2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater .

HY-76222

Isatoic anhydride	Drug Intermediate	Others
Isatoic anhydride is a single-adduct forming reagent and a monofunctional SHAPE reagent. Isatoic anhydride reacts with the 2'-hydroxyl group of RNA nucleotides via a single reactive group to form a single adduct, without forming cross-links between nucleotides. In SHAPE-JuMP experiments, Isatoic anhydride serves as a control reagent for single-adduct formation, which is used to distinguish true cross-links from single-adduct formation .

HY-W004289

Methyl pentadecanoate	Drug Derivative	Others
Methyl pentadecanoate is a fatty acid ester that can be isolated from extracts of L. wallichi. Methyl pentadecanoate is formed by the condensation of the carboxyl group of pentadecanoic acid with the hydroxyl group of methanol .

HY-15157

Calcitetrol 1α, 24, 25-Trihydroxy VD3	VD/VDR	Metabolic Disease
Calcitetrol(1α, 24, 25-Trihydroxy VD3) is the hormonally active form of vitamin D with three hydroxyl groups.

HY-W012971

5-Amino-1-pentanol	Biochemical Assay Reagents	Others
5-Amino-1-pentanol is a linker containing a hydroxyl group and amine group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

HY-W099630

Heptadecan-9-ol 9-Heptadecanol	Biochemical Assay Reagents	Others
Heptadecan-9-ol (9-Heptadecanol) is a lipid with a secondary hydroxyl group and two non-polar tails.

HY-P4632

H-γ-Glu-Leu-OH 1 Publications Verification γ-Glu-Leu	Amino Acid Derivatives	Others
H-γ-Glu-Leu-OH (γ-Glu-Leu) is a dipeptide consisting of γ-glutamic acid and leucine, terminated by a hydroxyl group .

HY-Y1374

Benzoic anhydride	Biochemical Assay Reagents	Others
Benzoic anhydride is a catalyst that can be used for organic synthesis reactions. Benzoic anhydride is used as a chemical titration reagent for selective quantification and deactivation of phenolic hydroxyl groups on the surface of carbon nanotubes .

HY-W460072

tert-Butyl 7-hydroxyheptanoate	Biochemical Assay Reagents	Others
tert-Butyl 7-hydroxyheptanoate is a linker with a hydroxyl group and a t-butyl ester. The hydroxyl group allows for further derivatization or replacement with many other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

HY-W039729

5-(Boc-amino)-1-pentanol	Biochemical Assay Reagents	Others
5-(Boc-amino)-1-pentanol is a linker containing a hydroxyl group and Boc-protected amino group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.

HY-174967C

4-Arm-PEG20000-OH	Biochemical Assay Reagents	Others
4-Arm-PEG20000-OH is a PEG derivative with a four-arm structure and a hydroxyl (OH) functional group. 4-Arm-PEG20000-OH reacts with functional groups on biomolecules (such as proteins, peptides, antibodies, etc.) through hydroxyl groups and can be used for drug delivery .

HY-W683499

Lauryl hydroxysultaine LHSB	Biochemical Assay Reagents	Others
Lauryl hydroxysultaine (LHSB), a surfactant, is comprised of a core Sultaine structure with a sulphopropyl quaternary ammonium salt, an alkyl group and a hydroxyl group .

HY-W016455

6-Bromo-1-hexanol	Biochemical Assay Reagents	Others
6-Bromo-1-hexanol posesses a terminal bromine and hydroxylic group. The bromine is a very good leaving group for nucleophilic substitution reactions. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

HY-W007345

2-Amino-5-fluorophenol 4-Fluoro-2-hydroxyaniline	Biochemical Assay Reagents	Others
2-Amino-5-fluorophenol is an isomer of aminofluorophenol and also a HONO generator. 2-Amino-5-fluorophenol reacts with nitrogen dioxide (NO₂) via two pathways to form nitrous acid (HONO): hydrogen abstraction from the hydroxyl group and hydrogen abstraction from the amino group, with both the amino and hydroxyl groups participating in the reaction in the transition state .

HY-151822

Hydroxy-PEG3-DBCO	ADC Linker	Others
Hydroxy-PEG3-DBCO is a click chemistry reagent containing an azide group. Hydroxy-PEG3-DBCO is a PEG linker containing a DBCO moiety and a terminal primary hydroxyl group. The hydroxyl can react with a variety of functional groups and the hydrophilic PEG spacer arm can provide better solubility to labeled molecules. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .

HY-D1067

NIR dye-1	Fluorescent Dye	Others
NIR dye-1 (Compound 1h) is a near-infrared (NIR) fluorescent dye. NIR dye-1 has absorption and emission in the NIR region, while retaining an optically tunable hydroxyl group .

HY-W190921

t-Butyl 3-(hydroxypropoxyl)-propanoate	Biochemical Assay Reagents	Others
t-Butyl 3-(hydroxypropoxyl)-propanoate contains reactive hydroxyl and t-butyl protected carboxyl moieties. The hydroxyl group can react to further derivatize the compound. The t-butyl carbonyl group can be deprotected under acidic conditions.

HY-E70241

3-Hydroxypropionyl-CoA	Endogenous Metabolite	Others
3-Hydroxypropionyl-CoA is a derivative of coenzyme A containing a hydroxyl group .

HY-174963C

DBCO-PEG2000-OH	Biochemical Assay Reagents	Others
DBCO-PEG2000-OH is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG2000-OH contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-174955B

mPEG5000-Silane	Biochemical Assay Reagents	Others
mPEG5000-Silane is a PEG derivative containing silane that can be used to modify glass, silicon or other surfaces by reacting the hydroxyl groups with ethoxy (methoxy) silane .

HY-174955A

mPEG2000-Silane	Biochemical Assay Reagents	Others
mPEG2000-Silane is a PEG derivative containing silane that can be used to modify glass, silicon or other surfaces by reacting the hydroxyl groups with ethoxy (methoxy) silane .

HY-W142194

Benzyl (5-hydroxypentyl)carbamate	DNA/RNA Synthesis	Cancer
Benzyl (5-hydroxypentyl)carbamate is a linker capable of repairing damaged DNA by binding to the 5'-hydroxyl group on the sugar backbone. Benzyl (5-hydroxypentyl)carbamate can also bind to DNA ligands and can inhibit cell proliferation in resistant cell lines. However, Benzyl (5-hydroxypentyl)carbamate is toxic to cells and can also cause DNA damage and strand breakage.

HY-W800822

Lactic acid dodecyl ester Lauryl lactate	Biochemical Assay Reagents	Others
Lactic acid dodecyl ester (Lauryl lactate) is a lipid with a terminal hydroxyl group at the head. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

HY-W174661

tert-Butyl 6-hydroxyhexanoate	Biochemical Assay Reagents	Others
tert-Butyl 6-hydroxyhexanoate is a linker with a hydroxyl group and a t-butyl ester. The hydroxyl group allows for further derivatization or replacement with many other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

HY-W591962

5-Azidopentan-1-ol 1-Pentanol, 5-azido-	Biochemical Assay Reagents	Others
5-Azidopentan-1-ol (1-Pentanol, 5-azido-) is a linker containing an azide group and a terminal hydroxyl group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

HY-174967A

4-Arm-PEG5000-OH	Biochemical Assay Reagents	Others
4-Arm-PEG5000-OH is a PEG derivative with a four-arm structure and a hydroxyl (OH) functional group. 4-Arm-PEG5000-OH reacts with functional groups on biomolecules (such as proteins, peptides, antibodies, etc.) through hydroxyl groups and can be used for drug delivery .

HY-W250446

(R)-Methyl 3-hydroxydecanoate	Biochemical Assay Reagents	Others
(R)-Methyl 3-hydroxydecanoate is an enantiomerically pure hydroxylated fatty acid methyl ester. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

HY-135580A

Raloxifene Bismethyl Ether hydrochloride	Drug Metabolite	Endocrinology
Raloxifene Bismethyl Ether hydrochloride is a metabolite of Raloxifene and an estrogen receptor inactive compound on which both hydroxyl groups are absent .

HY-135580

Raloxifene Bismethyl Ether	Drug Metabolite	Endocrinology
Raloxifene Bismethyl Ether is a metabolite of Raloxifene and an estrogen receptor inactive compound on which both hydroxyl groups are absent .

HY-W1120392

HO-PEG36-OH	Biochemical Assay Reagents	Others
HO-PEG36-OH is a PEG derivative with a hydroxyl (OH) functional group that can be used for drug delivery .

HY-174951

Pyrene-PEG1000-OH	Biochemical Assay Reagents	Others
Pyrene-PEG1000-OH is a PEG derivative with Pyrene and hydroxyl (OH) functional groups that can be used for drug delivery .

HY-174931

HO-PEG1000-NH-Fmoc	Biochemical Assay Reagents	Others
HO-PEG1000-NH-Fmoc is a PEG derivative with an Fmoc protecting group and a hydroxyl (OH) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction.

HY-N9332

Kalopanax saponin G	Others	Others
Kalopanax saponin G is an ester glycoside of oleanolic acid possessing no sugar moiety at the C-3 hydroxyl group. Kalopanax saponin G is isolated from the bark of Kalopanax pictus .

HY-174963D

DBCO-PEG3400-OH	Biochemical Assay Reagents	Others
DBCO-PEG3400-OH is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG3400-OH contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-174963B

DBCO-PEG1000-OH	Biochemical Assay Reagents	Others
DBCO-PEG1000-OH is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG1000-OH contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-174963E

DBCO-PEG5000-OH	Biochemical Assay Reagents	Others
DBCO-PEG5000-OH is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG5000-OH contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-174963A

DBCO-PEG600-OH	Biochemical Assay Reagents	Others
DBCO-PEG600-OH is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG600-OH contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-174963

DBCO-PEG400-OH	Biochemical Assay Reagents	Others
DBCO-PEG400-OH is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG400-OH contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-174955

mPEG1000-Silane	Biochemical Assay Reagents	Others
mPEG1000-Silane is a PEG derivative containing silane that can be used to modify glass, silicon or other surfaces by reacting the hydroxyl groups with ethoxy (methoxy) silane .

HY-E70037

GlcNAc kinase (EcNagK) N-Acetylglucosamine kinase	Endogenous Metabolite	Metabolic Disease
GlcNAc kinase (EcNagK) (N-Acetylglucosamine kinase) is a GlcNAc-metabolizing enzyme. GlcNAc kinase (EcNagK) transfers the gamma-phosphoryl group of an ATP onto the hydroxyl group at the C-6 of GlcNAc to generate a GlcNAc-6-P .

HY-174948

NHS-PEG1000-CHO NHS-PEG1000-Aldehyde	Biochemical Assay Reagents	Others
NHS-PEG1000-CHO (NHS-PEG1000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .

HY-174948C

NHS-PEG5000-CHO NHS-PEG5000-Aldehyde	Biochemical Assay Reagents	Others
NHS-PEG5000-CHO (NHS-PEG5000-Aldehyde) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .

HY-W190939

C11-PEG9-alcohol	Biochemical Assay Reagents	Others
C11-PEG9-alcohol is a linker with an aliphatic carbon chain and a PEG chain. The hydrophilic PEG chain increases the water solubility of the compounds in the aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

Cat. No.	Product Name

HY-L0104V

UORSY New Generation Screening Library

1,900,000 compounds

UORSY New Generation Screening Library contains about 1,900,000 compounds. The library is a revolutionary collection of lead-like molecules with outstanding structural quality and diversity—New Generation Screening Library (NGSL). Its core is decorated with interesting building blocks, including important medicinal fragments such as peptide bonds, amino groups and hydroxyl groups. and designed for discovery of new Voltage-gated calcium channel blockers.

HY-L914

Serine/Threonine Focused Covalent Fragment Library

3,208 compounds

In the research of covalent inhibitors targeting serine and threonine, scientists have found that the nucleophilicity of these hydroxyl groups is significantly enhanced due to the influence of their surrounding environment. This results in higher activity during catalytic reactions. Aspirin, which targets the non-catalytic domain serine (Ser529 in human COX1) of cyclooxygenase, exerts its anti-inflammatory effect through covalent binding. β-lactam antibiotics, which targets the catalytic domain serine of penicillin-binding proteins, interferes with bacterial cell wall synthesis.

Through careful selection, we constructed a structural filter containing over 110 electrophilic groups. By analyzing the electrophilic fragments selected by the structural filter, we removed any molecules with trivial or undesirable structural features. Ultimately, we obtained 3,300 fragment molecules which can target serine and threonine residues and can be used for fragment-based covalent drug discovery.

Cat. No.	Product Name	Type

HY-W127711

Fast Blue B Salt, Dye content ~95%

Fluorescent Dye

Fast Blue B Salt, Dye content ~95% is a diazo dye, primarily used as a chromogenic substrate in biochemical analysis. Fast Blue B Salt, Dye content ~95% is the coupling agent for the histochemical demonstration of proteases. Fast Blue B Salt, Dye content ~95% can be used for the detection of acid phosphatase in Clostridium perfringens, and also for the determination of lipase activity. Fast Blue B Salt, Dye content ~95% reacts directly with the active hydroxyl groups in phenolic compounds to determine the content of phenolic substances .

HY-D2882

RB-PEG400-OH Rhodamine B-PEG400-OH	Fluorescent Dye
RB-PEG400-OH (Rhodamine B-PEG400-OH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a Hydroxyl group. RB-PEG400-OH can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .

HY-D1067

NIR dye-1	Fluorescent Dye
NIR dye-1 (Compound 1h) is a near-infrared (NIR) fluorescent dye. NIR dye-1 has absorption and emission in the NIR region, while retaining an optically tunable hydroxyl group .

HY-D2796B

FITC-PEG5000-OH	Fluorescent Dye
FITC-PEG5000-OH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Hydroxyl group. FITC-PEG5000-OH can be used for fluorescent labeling and imaging .

HY-D2796C

FITC-PEG10000-OH	Fluorescent Dye
FITC-PEG10000-OH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Hydroxyl group. FITC-PEG10000-OH can be used for fluorescent labeling and imaging .

HY-D2796

FITC-PEG400-OH	Fluorescent Dye
FITC-PEG400-OH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Hydroxyl group. FITC-PEG400-OH can be used for fluorescent labeling and imaging .

HY-D2796A

FITC-PEG1000-OH	Fluorescent Dye
FITC-PEG1000-OH is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a Hydroxyl group. FITC-PEG1000-OH can be used for fluorescent labeling and imaging .

HY-D2882B

RB-PEG1000-OH Rhodamine B-PEG1000-OH	Fluorescent Dye
RB-PEG1000-OH (Rhodamine B-PEG1000-OH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a Hydroxyl group. RB-PEG1000-OH can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .

HY-D2882E

RB-PEG5000-OH Rhodamine B-PEG5000-OH	Fluorescent Dye
RB-PEG5000-OH (Rhodamine B-PEG5000-OH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a Hydroxyl group. RB-PEG5000-OH can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .

HY-D2882A

RB-PEG600-OH Rhodamine B-PEG600-OH	Fluorescent Dye
RB-PEG600-OH (Rhodamine B-PEG600-OH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a Hydroxyl group. RB-PEG600-OH can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .

HY-D2882H

RB-PEG10000-OH Rhodamine B-PEG10000-OH	Fluorescent Dye
RB-PEG10000-OH (Rhodamine B-PEG10000-OH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a Hydroxyl group. RB-PEG10000-OH can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .

HY-D2882C

RB-PEG2000-OH Rhodamine B-PEG2000-OH	Fluorescent Dye
RB-PEG2000-OH (Rhodamine B-PEG2000-OH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a Hydroxyl group. RB-PEG2000-OH can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .

HY-D2882D

RB-PEG3400-OH Rhodamine B-PEG3400-OH	Fluorescent Dye
RB-PEG3400-OH (Rhodamine B-PEG3400-OH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a Hydroxyl group. RB-PEG3400-OH can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .

Cat. No.	Product Name	Target	Research Area

HY-P10069

Ac-pSar12-OH	Drug Intermediate ADC Linker	Others
Ac-pSar12-OH is a water-soluble polymer of the polysarcosine class and can be used as a linker. Ac-pSar12-OH is a linear polypeptide derivative composed of 12 arginine units. Ac-pSar12-OH N-terminus is modified with an acetyl group, while the C-terminus retains a free hydroxyl group, which can help enhance the stability of the polypeptide .

HY-P4632

H-γ-Glu-Leu-OH 1 Publications Verification γ-Glu-Leu	Amino Acid Derivatives	Others
H-γ-Glu-Leu-OH (γ-Glu-Leu) is a dipeptide consisting of γ-glutamic acid and leucine, terminated by a hydroxyl group .

Cat. No.	Product Name

HY-KE8012

Protein Deglycosylation Kit(for O-linked Glycans)

Protein Deglycosylation Kit (for O-linked Glycans)contains O-Glycosidase and a2-3,6,8,9 Neuraminidase.Both enzymes are crucial tool enzymes for glycosylation research and are used in combination to enzymatically release O-linked glycans from glycoproteins.O-Glycosidase is capable of cleaving and releasing Core 1 (Gal-B(1-3)-GalNAc-)and Core 3(GIcNAc-B(1-3)-GalNAc-)O-linked disaccharides,which are linked to the hydroxyl groups of Ser or Thr residues in glycoproteins.a2-3,6,8,9 Neuraminidase can remove a(2,3)-,a(2,6)-,a(2,8)-,and a(2,9)-sialic acid residues from the non-reducing termini of O-linked glycans.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-107486

Nosiheptide Multhiomycin; RP 9671	Infection Microorganisms Antibiotics Animal Husbandry Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Antibiotic
Nosiheptide (Multhiomycin), a thiopeptide antibiotic produced by Streptomyces actuosus, inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Nosiheptide has been widely used as a feed additive for animal growth .

HY-134222A

N-Acetylserine N-Acetyl-L-serine	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Complement System
N-Acetylserine (N-Acetyl-L-serine) is a complement pathway modulator targeting activated third complement protein (C3b) and an amino-terminal residue (an N-terminal acetylation modification group). N-Acetylserine reacts with the exposed thioester group of C3b via its hydroxyl group, thereby blocking the covalent binding of glycerol to this thioester group. N-Acetylserine widely exists in soluble proteins of mammalian cells (accounting for approximately 80% of such proteins). N-Acetylserine has a blocking property that prevents direct Edman sequencing of proteins; deblocking is achievable through trifluoroacetic acid-catalyzed N→O acetyl migration followed by β-elimination. N-Acetylserine is suitable for sequencing of proteins with N-terminal acetylserine modification .

HY-N2436

2,3-Dihydroxysuccinic acid Tartaric acid	Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Biochemical Assay Reagents
2,3-Dihydroxysuccinic acid (Tartaric acid) is an organic acid containing two hydroxyl groups and two carboxyl groups. 2,3-Dihydroxysuccinic acid exists in various stereoisomers and is widely used in food, pharmaceutical, chemical, and other fields .

HY-Y0801

2,6-Dihydroxybenzoic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields Source Classification	Drug Metabolite
2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater .

HY-W047187

Lavandoside	Structural Classification other families Onychium japonicum (Thunb.) Kunze Ketones, Aldehydes, Acids Plants	Xanthine Oxidase NO Synthase TNF Receptor
Lavandoside is an ABTS ^?+ free radical scavenger and a moderate inhibitor of xanthine oxidase (XO), with an IC₅₀ of 71.6 μM for inhibiting NO production in LPS-induced macrophages. Lavandoside exerts its antioxidant and potential anti-inflammatory effects by directly scavenging free radicals and inhibiting XO activity, a mechanism related to the hydroxyl groups in its molecular structure. Lavandoside can be isolated from lavender and can be used in the development of natural antioxidants and in research on oxidative stress-related diseases and inflammation-related diseases .

HY-151852

9AzNue5Ac	Cardiovascular Disease Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
9AzNue5Ac, 9-azido-9-deoxy-N-acetylneuraminic acid, is a click chemistry reagent and a Neu5Ac analogue with the substitution of 9-hydroxyl group with an azide. 9AzNue5Ac could be metabolized and incorporated into sialoglycans in living cells and mice. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-W015936

(E)-Hex-2-en-1-ol trans-Hex-2-en-1-ol	Source Classification	Environmental Pollutants Biochemical Assay Reagents
(E)-Hex-2-en-1-ol belongs to the class of unsaturated alcohols consisting of a six-carbon chain with a double bond between carbon atoms 2 and 3 and a hydroxyl group attached to carbon atom 1. The compound has a grassy or herbaceous smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It can also be used as a fragrance ingredient in personal care products and as a starting material for the synthesis of other organic compounds. Furthermore, (E)-hex-2-en-1-ol can be used as a solvent or reagent in various chemical reactions.

HY-W004289

Methyl pentadecanoate	Structural Classification other families Classification of Application Fields Other Diseases Plants Disease Research Fields Lipid Source Classification	Drug Derivative
Methyl pentadecanoate is a fatty acid ester that can be isolated from extracts of L. wallichi. Methyl pentadecanoate is formed by the condensation of the carboxyl group of pentadecanoic acid with the hydroxyl group of methanol .

HY-W021265

Cyclohexane-1,2,3,4,5,6-hexaol Cyclohexane-1,2,3,4,5,6-hexol	Microorganisms Source Classification	Biochemical Assay Reagents
Cyclohexane-1,2,3,4,5,6-hexaol, also known as inositol or inositol, is a cyclic sugar alcohol consisting of a six-carbon ring with six hydroxyl groups. This compound is important for its biological activity and is widely distributed in nature, especially in plant and animal tissues. It plays a role in various physiological processes such as signal transduction, osmoregulation and lipid metabolism. In addition, Cyclohexane-1,2,3,4,5,6-hexaol has potential investigational effects, including improving conditions related to insulin resistance, polycystic ovary syndrome, and mental health conditions. It can also be used as a supplement in animal feed and human nutritional products.

HY-W021267

3-Demethylcolchicine	Alkaloids Structural Classification Monophenols other families Classification of Application Fields Other Alkaloids Phenols Plants Inflammation/Immunology Disease Research Fields Source Classification	Reactive Oxygen Species (ROS)
3-Demethylcolchicine, a colchicine metabolite and anti-inflammatory agent, exhibits potent tubulin-binding activity. 3-Demethylcolchicine inhibits carrageenan-induced rat paw edema. 3-Demethylcolchicine bears a hydroxyl group on its carbocyclic ring; this group participates in free radical scavenging processes, allowing it to act as a free radical scavenger. 3-Demethylcolchicine is applicable to studies related to carrageenan-induced paw edema .

HY-W007671

H-Tyr-OMe 1 Publications Verification	Monophenols Classification of Application Fields Other Diseases Phenols Amino acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Tyrosinase
H-Tyr-OMe is an endogenous metabolite. H-Tyr-OMe quenches the fluorescence of carbon dots by oxidizing the phenolic hydroxyl group to quinone under the catalysis of Tyrosinase, and its amino and thiol binding ability can respond to changes in the concentration of biothiols .

HY-134493

Butyrate-Vitamin D3 Butyrate-Cholecalciferol; Butyrate-Colecalciferol	Natural Products Endogenous metabolite Source Classification	VD/VDR
Butyrate-Vitamin D3 (Butyrate-Cholecalciferol) is a derivative of vitamin D3 in which a hydroxyl group in the vitamin D3 molecule is replaced by a butyric acid group. Butyrate-Vitamin D3 affects gene expression and cell function and has certain anti-inflammatory effects. Butyrate-Vitamin D3 can be used in the study of immune regulation, metabolic diseases and cancer .

HY-E70007

Catechol O-methyltransferase, porcine liver COMT	Natural Products Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Catechol O-methyltransferase, porcine liver (COMT), the magnesium-dependent transfer of methyl groups from S-adenosyl methionine to a hydroxyl group on dopamine, converting it to 3-methoxytyramine. Catechol O-methyltransferase has two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). Catechol O-methyltransferase is to regulate epinephrine, norepinephrine, and dopamine levels in the brain .

HY-107486R

Nosiheptide (Standard) Multhiomycin (Standard); RP 9671 (Standard)	Structural Classification Microorganisms Antibiotics Animal Husbandry Antibacterial Disease Research Other Antibiotics Source Classification	Reference Standards Bacterial Antibiotic
Nosiheptide (Standard) is the analytical standard of Nosiheptide. This product is intended for research and analytical applications. Nosiheptide (Multhiomycin), a thiopeptide antibiotic produced by Streptomyces actuosus, inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Nosiheptide has been widely used as a feed additive for animal growth .

HY-N2436R

2,3-Dihydroxysuccinic acid (Standard) Tartaric acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Biochemical Assay Reagents Reference Standards
2,3-Dihydroxysuccinic acid (Standard) (Tartaric acid (Standard)) is the analytical standard of 2,3-Dihydroxysuccinic acid (HY-N2436). This product is intended for research and analytical applications. 2,3-Dihydroxysuccinic acid (Tartaric acid) is an organic acid containing two hydroxyl groups and two carboxyl groups. 2,3-Dihydroxysuccinic acid exists in various stereoisomers and is widely used in food, pharmaceutical, chemical, and other fields.

HY-N16396

Ampelanol	Quinones Microorganisms Anthraquinones Source Classification	Drug Derivative
Ampelanol is a derivative of Altersolanol A (HY-125461). Ampelanol has no anticancer and anti-inflammatory activity through the reduction of one of a carbonyl group and removal of hydroxyl substituents within Altersolanol A. Ampelanol can be used as a negative control .

HY-N9332

Kalopanax saponin G	Triterpenes Structural Classification Classification of Application Fields Terpenoids Kalopanax septemlobus (Thunb.) Koidz. Other Diseases Plants Pentacyclic Triterpenoids Disease Research Fields Araliaceae Source Classification	Others
Kalopanax saponin G is an ester glycoside of oleanolic acid possessing no sugar moiety at the C-3 hydroxyl group. Kalopanax saponin G is isolated from the bark of Kalopanax pictus .

HY-W007671R

H-Tyr-OMe (Standard)	Monophenols Phenols Amino acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Tyrosinase
H-Tyr-OMe is an endogenous metabolite. H-Tyr-OMe quenches the fluorescence of carbon dots by oxidizing the phenolic hydroxyl group to quinone under the catalysis of Tyrosinase, and its amino and thiol binding ability can respond to changes in the concentration of biothiols .

HY-Y0801R

2,6-Dihydroxybenzoic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Phenols Polyphenols Endogenous metabolite Source Classification	Reference Standards Drug Metabolite
2,6-Dihydroxybenzoic acid (Standard) is the analytical standard of 2,6-Dihydroxybenzoic acid (HY-Y0801). This product is used for research and analytical applications. 2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater .

HY-118118

Phlebiakauranol aldehyde	Microorganisms Antibiotics Other Antibiotics Source Classification	Fungal
Phlebiakauranol aldehyde is an antifungal and cytotoxic metabolite with strong antifungal activity. Phlebiakauranol aldehyde exhibits significant antibacterial and cytotoxic activities against a variety of plant pathogens. The aldehyde group and high number of hydroxyl groups of Phlebiakauranol aldehyde are considered to be the main reasons for its biological activity. The two acetic acid derivatives of Phlebiakauranol aldehyde only exhibit very weak antifungal and antibacterial activities and moderate cytotoxic activity .

HY-136933R

Gitoxin (Standard)	Digitalis purpurea Linn. Structural Classification Scrophulariaceae Plants Steroids Source Classification	Reference Standards Na+/K+ ATPase
Gitoxin (Standard) is the analytical standard of Gitoxin. This product is intended for research and analytical applications. Gitoxin, a Na+/K+-ATPase inhibitor, usually appears as a result of metabolic degradation of Digitoxin, is just the hydroxyl (ZOH) group close to the C-17β position, which changes the pharmacokinetics and pharmacodynamics of these substances considerably .

HY-137566

Cucumarioside H	Triterpenes Animals Terpenoids Source Classification	Mitochondrial Metabolism
Cucumarioside H is a novel triterpene glycoside isolated from the Far Eastern sea cucumber Eupentacta fraudatrix, including H2, H3 and H4. These glycosides have a branched pentasyl structure with a rare 3-O-methyl-D-xylose as the terminal monosaccharide. H2 contains 23,24,25,26,27-pentanolone sterols and has an 18(16)-lactone, which is not common in sea cucumbers. The glycoside portion of H3 contains an extremely rare ethoxyl radical at the 25 position, which may be an artifact formed during the long ethanol extraction process. Studies have shown that H1-3 are cytotoxic to mouse spleen lymphocytes, hemolytic to mouse erythrocytes, and cytotoxic to Ehrlich carcinoma cells. The presence of a 25-hydroxyl group in the glycoside portion significantly reduces these activities.

HY-N15727

2,5-Dimethylchromone-7-O-β-D-glucopyranoside	Rheum australe D. Don Polygonaceae Plants Saccharides Monosaccharides Source Classification	Others
2,5-Dimethylchromone-7-O-β-D-glucopyranoside is an orally active chromone glycoside found in the underground parts of Rheum australe. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside shows a DPPH radical scavenging activity with an IC₅₀ value of 66.9 μM. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside scavenges free radicals by providing hydrogen atoms through phenolic hydroxyl groups, inhibiting lipid peroxidation. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside is promising for research of oxidative stress-related diseases such as inflammation and skin diseases .

HY-N8737

Desrhamnosylmartynoside	Monophenols Labiatae Phenols Plants Seriphidium transiliense Source Classification	Others
Desrhamnosylmartynosideis extracted from the root of Scutellaria prostrata. Desrhamnosylmartynoside has absorption bands assignable to hydroxyl,α,β-unsanturate carbonyl groups .

HY-N17839

Senbusine A	Structural Classification Alkaloids Other Alkaloids Ranunculaceae Aconitum carmichaeli Debx. Plants Source Classification	Drug Derivative
Senbusine A (compound 4) is a diterpenic alkaloid found in the dried roots of Aconitum carmichaeli from China. Senbusine A acts as an intermediate in the biosynthesis of aconitine .

HY-N19879

Obliquetin	Structural Classification Rutaceae Coumarins Ptaeroxylon obliquum (Thunb.) Radlk. Phenylpropanoids Plants Source Classification	Drug Derivative
Obliquetin is a coumarin derivative of aesculetin and 6-monomethyl ether of obliquetol, found in the heartwood of Ptaeroxylon obliquum .

HY-N18104

Picrasin G	Structural Classification Simaroubaceae Ketones, Aldehydes, Acids Plants Picrasma quassioides(D．Don)Benn． Source Classification	Others
Picrasin G is a bitter principle. Picrasin G can be isolated from Picrasma quassioides .

HY-180749

L-4-Hydroxyglutamate semialdehyde	Structural Classification Alkaloids Other Alkaloids Endogenous metabolite Source Classification	Nucleoside Antimetabolite/Analog
L-4-Hydroxyglutamate semialdehyde is a derivative of glutamate semialdehyde, with a hydroxyl group introduced at the 4-position of L-glutamic 5-semialdehyde. L-4-Hydroxyglutamate semialdehyde functions as a metabolite in yeast, mice, and humans, and is functionally associated with L-glutamic 5-semialdehyde, playing a role in arginine and proline metabolism .

HY-N17138

threo-1-(4-Hydroxyphenyl)-1-methoxy-2,3-propanediol	Structural Classification Monophenols Pinaceae Abies delavayi Franch. Phenols Plants Source Classification	Others
threo-1-(4-Hydroxyphenyl)-1-methoxy-2,3-propanediol is an aromatic propanediol phenolic derivative containing methoxy and hydroxyl groups. It can be naturally extracted from the dried aerial parts of Abies delavayi Franch. var. delavayi (Cangshan fir) from Dali, Yunnan, China. This source plant produces anti-inflammatory and anti-tumor active components .

HY-N19720

Bractein	Structural Classification Crotalaria albida Heyne ex Roth Phenols Polyphenols Plants Compositae Source Classification	Drug Derivative Parasite
Bractein is a natural aurone flavonoid with potential antioxidant activity. Bractein shows in vitro antileishmanial activity and inhibits promastigotes and intracellular amastigotes of Leishmania donovani. Bractein exhibits no obvious cytotoxicity against mammalian macrophages with an EC₅₀ value > 25.0 μg/mL. Bractein can be used for the research of Leishmania .

HY-N13081

3-Oxo-cinobufagin	Microorganisms Steroids Source Classification	Others
3-Oxo-cinobufagin (compound 8) is a potential anticancer compound that can be isolated from the broth of M. spinosus by high-performance liquid chromatography. Compared to other isolated compounds, the hydroxyl group at the C-5 position of 3-Oxo-cinobufagin is further oxidized or isomerized, significantly reducing its cytotoxic activity against most cell lines (except HEL), while increasing its activity against the BEL cell line. The IC50 values of 3-Oxo-cinobufagin's cytotoxicity against cancer cells are: 71.3 μM (HepG2), 90.2 μM (SMMC-7221), 0.11 μM (BEL-7402), 72.5 μM (K562), 5.3 μM (HL-60), and 12 nM (HEL) .

Cat. No.	Product Name	Chemical Structure

HY-114296S

2,3-Oxidosqualene-d6

2,3-Oxidosqualene-d₆ (Squalene oxide-d₆) is a deuterium labeled 2,3-Oxidosqualene (HY-114296). 2,3-Oxidosqualene (Squalene oxide) is a sterol biosynthesis precursor intermediate.2,3-Oxidosqualene participates in cyclization pathways that form sterols and triterpenes, and contributes to introduction of their characteristic 3-hydroxyl group.2,3-Oxidosqualene forms metabolically from squalene in rat liver homogenates under sterol synthesis conditions.2,3-Oxidosqualene converts to sterols including cholesterol, lathosterol, and lanost-8-en-3β-ol in rat liver homogenates under anaerobic conditions.

HY-W010505S

Hexane-1,6-diol-d4
Hexane-1,6-diol-d₄ is the deuterium labeled Hexane-1,6-diol (HY-W010505). Hexane-1,6-diol is a 6-carbon straight-chain diol with hydroxyl groups at both ends. Hexane-1,6-diol can be used as an additive for drilling fluids. Hexane-1,6-diol can also be used as a substrate in life science-related research .

Cat. No.	Product Name		Classification

HY-103006

NAI-N3 5 Publications Verification		Azide
NAI-N3 is a RNA acylation reagent that enables RNA purification. NAI-N3 is a dual-function SHAPE (selective 2-hydroxyl acylation and profiling experiment) probe (RNA structure probe and enrichment) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151852

9AzNue5Ac		Labeling and Fluorescence Imaging Azide
9AzNue5Ac, 9-azido-9-deoxy-N-acetylneuraminic acid, is a click chemistry reagent and a Neu5Ac analogue with the substitution of 9-hydroxyl group with an azide. 9AzNue5Ac could be metabolized and incorporated into sialoglycans in living cells and mice. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-101532

6A-Azido-6A-deoxy-β-cyclodextrin β-CDN3; 6A-deoxy-6A-azido-β-cyclodextrin		Azide
6A-Azido-6A-deoxy-β-cyclodextrin (β-CDN3) is a site-specifically modified β-cyclodextrin with a single azido group replacing the hydroxyl group at the C6 position. 6A-Azido-6A-deoxy-β-cyclodextrin forms a host-guest inclusion complex with Dexamethasone (HY-14648), localizing the drug within its hydrophobic cavity, which restricts the rotational mobility of the drug and places Dexamethasone in a less polar environment. 6A-Azido-6A-deoxy-β-cyclodextrin acts as a coupling agent to graft β-cyclodextrin onto thermosensitive nanogels via strain-promoted alkyne-azide cycloaddition (SPAAC). 6A-Azido-6A-deoxy-β-cyclodextrin also serves as a click chemistry reagent. It contains an azide group and undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules bearing an alkyne group. It also undergoes strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .

HY-151822

Hydroxy-PEG3-DBCO		DBCO
Hydroxy-PEG3-DBCO is a click chemistry reagent containing an azide group. Hydroxy-PEG3-DBCO is a PEG linker containing a DBCO moiety and a terminal primary hydroxyl group. The hydroxyl can react with a variety of functional groups and the hydrophilic PEG spacer arm can provide better solubility to labeled molecules. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .

HY-174963C

DBCO-PEG2000-OH		DBCO
DBCO-PEG2000-OH is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG2000-OH contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-174963D

DBCO-PEG3400-OH		DBCO
DBCO-PEG3400-OH is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG3400-OH contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-174963B

DBCO-PEG1000-OH		DBCO
DBCO-PEG1000-OH is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG1000-OH contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-174963E

DBCO-PEG5000-OH		DBCO
DBCO-PEG5000-OH is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG5000-OH contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-174963A

DBCO-PEG600-OH		DBCO
DBCO-PEG600-OH is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG600-OH contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-174963

DBCO-PEG400-OH		DBCO
DBCO-PEG400-OH is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG400-OH contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-W800664

5-(Azido-PEG4)-pent-2-yn-1-ol		Azide
5-(Azido-PEG4)-pent-2-yn-1-Ol is a PEG linker containing an azide group and a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

HY-174963H

DBCO-PEG10000-OH		DBCO
DBCO-PEG10000-OH is a PEG derivative composed of DBCO, PEG, and hydroxyl groups. DBCO-PEG10000-OH contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-140810

3-(Azido-PEG5-amino)propanol		Azide
3-(Azido-PEG5-amino)propanol is a PEG linker which contains an azide moiety and a hydroxyl group. 3-(Azido-PEG5-amino)propanol is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups.

Cat. No.	Product Name		Classification

HY-Y0850E

Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) 3 Publications Verification PVA (Mw 30000-70000, 87-90% hydrolyzed); Poly(Ethenol) (Mw 30000-70000, 87-90% hydrolyzed)		Polymers
Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 30000-70000 and hydrolytic properties. The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process. Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. A degree of hydrolysis of 87-90% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipients .

HY-Y0850J

Polyvinyl alcohol (Mw 13000-23000, 87-89% hydrolyzed) 3 Publications Verification PVA (Mw 13000-23000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 13000-23000, 87-89% hydrolyzed)		Polymers
Polyvinyl alcohol (Mw 13000-23000, 87-89% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 130000-23000 and hydrolytic properties. Polyvinyl alcohol (Mw 13000-23000, 87-89% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate and polyvinyl alcohol is obtained. A degree of hydrolysis of 87-89% indicates that a large part of the acetate groups have been removed, resulting in a large number of hydroxyl groups in the PVA structure. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipient. Polyvinyl alcohol can be used in tissue engineering by electrospinning. Polyvinyl alcohol can achieve high cellular density, infiltration, and uniform distribution, facilitating functional connections between cells. Polyvinyl alcohol can improve cell vitality through in vitro cultivation. Polyvinyl alcohol demonstrates promising inhibition of ostersarcoma cancer cells with Doxorubicin (HY-15142A) .

HY-137697D

ddCTP trisodium solution (100 mM)		Nucleotide Analogs
ddCTP trilithium solution (100 mM) is a chain-terminating dideoxynucleotide. ddCTP trilithium is a type of chain-terminating deoxynucleotide. ddCTP trilithium can be incorporated into the extension primer chain that lacks the 3'-hydroxyl group, thereby terminating primer extension, viral genome replication, and DNA synthesis. ddCTP trilithium can distinguish almost identical RNA through distinguishable extension products in primer extension inhibition experiments. ddCTP trilithium is the active metabolite of Zalcitabine (HY-17392), which can competitively inhibit HIV reverse transcriptase, terminate the synthesis of viral DNA chains, and thereby inhibit HIV replication .

HY-137697

ddCTP		Nucleotide Analogs
ddCTP is a type of chain-terminating deoxynucleotide. ddCTP can be incorporated into the extension primer chain that lacks the 3'-hydroxyl group, thereby terminating primer extension, viral genome replication, and DNA synthesis. ddCTP can distinguish almost identical RNA through distinguishable extension products in primer extension inhibition experiments. ddCTP is the active metabolite of Zalcitabine (HY-17392), which can competitively inhibit HIV reverse transcriptase, terminate the synthesis of viral DNA chains, and thereby inhibit HIV replication .

HY-171574

3′-Azido-2′,3′-dideoxy-CTP AZddCTP		Nucleotide Analogs Cytidine Nucleotide
3′-Azido-2′,3′-dideoxy-CTP (AZddCTP) is a cytidine analog containing a 3-azido group. As a chain terminator, 3′-Azido-2′,3′-dideoxy-CTP can be incorporated into the nascent DNA chain by HIV reverse transcriptase. 3′-Azido-2′,3′-dideoxy-CTP terminates DNA synthesis due to the lack of a 3'-hydroxyl group, thereby inhibiting viral replication. 3′-Azido-2′,3′-dideoxy-CTP has IC₅₀ values of 15.6 μM and 160.8 μM for WT HIV and AZT ^R HIV. 3′-Azido-2′,3′-dideoxy-CTP has antiviral activity .

HY-W013156

2′,3′,5′-Triacetylinosine 2′,3′,5′-Tri-O-acetylinosine		Nucleoside Analogs Inosine
2′,3′,5′-Triacetylinosine (2′,3′,5′-Tri-O-acetylinosine) has been shown to inhibit the growth of cancer cells, and is also an efficient method for bond cleavage and radiation protection. 2',3',5'-Tri-O-acetylinosine has been shown to bind to pyridinium ions, and it has been used in the synthesis of tetrapeptides with hydroxyl groups or alkylation.

HY-158861

C3-K2-E14 G1-nPr-C14E		Cationic Lipids
C3-K2-E14 is a multi-ionizable amino-lipid featuring a central tertiary amine with two identical branches and an n-propyl group. Each branch features a propanamide linking to a branched amine, each with two C14 arms and a hydroxyl. Ionizable lipids such as this may be applied in the development of lipid nanoparticles for drug discovery.

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