1 Result for "

hyperadrenocorticism

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "hyperadrenocorticism" in MCE Product Catalog:

pTH (1-84) (dog)
pTH (1-84) (dog)
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Cat. No.: HY-P4827
CAS No.: 521986-14-1
Target:  

PTHR

Research Areas:  

Metabolic Disease

pTH (1-84) dog is a biologically active full-length canine parathyroid hormone, as well as an agonist of PTHR. pTH (1-84) dog can be detected by the "intact" PTH (W-PTH) assay, thus effectively distinguishing inactive C-terminal fragments. In terms of metabolic regulation, it rapidly and persistently stimulates hepatic glucose release, hepatic alanine uptake, and alanine-based gluconeogenesis in conscious fasted dogs, and causes a secondary increase in circulating canine insulin levels due to enhanced glucose release. However, high doses of pTH (1-84) (dog) may induce adverse reactions such as hypercalcemia in dogs. Based on the above characteristics, this hormone can be widely used in studies related to canine hyperadrenocorticism (HAC) .
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