90 Results for "

interleukin-6 (IL-6)

" in MedChemExpress (MCE) Product Catalog:
Products (90)

90 Results for "interleukin-6 (IL-6)" in MCE Product Catalog:

60
60 Publications Verification
Cat. No.: HY-P7044
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth Factor; Prev. IFNB2; IFN-Beta-2; IL-6; BSF-2; interleukin-6; CDF; BSF2; interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation Factor; HSF; Truncated interleukin 6; B-Cell Stimulatory Factor 2; Interferon, Beta 2; CTL Differ
Species:  
Human
Source:  
E. coli
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47
47 Cited Publications
Cat. No.: HY-P9917
CAS No.: 375823-41-9
Synonyms: Anti-Human IL6R, Humanized Antibody; RG-1569; rhPM-1
Tocilizumab (Anti-Human IL6R, Humanized Antibody) is an anti-human interleukin-6 receptor (IL-6R) neutralizing antibody, prevents binding of IL-6 to the IL-6R, thereby inhibiting both classic and trans-signaling. Tocilizumab (Anti-Human IL6R, Humanized Antibody) can be used for the treatment of rheumatoid arthritis . Tocilizumab is remarkablely effective for the study of severe COVID-19 (coronavirus disease) .
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33
33 Cited Publications
Cat. No.: HY-P7063
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth Factor; Prev. IFNB2; IFN-Beta-2; IL-6; BSF-2; interleukin-6; CDF; BSF2; interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation Factor; HSF; Truncated interleukin 6; B-Cell Stimulatory Factor 2; Interferon, Beta 2; CTL Differentiation Factor; interleukin BSF-2; interleukin 6; Interferon Beta-2
Species:  
Mouse
Source:  
E. coli
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4
4 Cited Publications
Cat. No.: HY-P9956
CAS No.: 541502-14-1
Synonyms: CNTO-328

Target:  

Interleukin Related

Research Areas:  

Cancer

Siltuximab is an anti-IL-6 (interleukin-6) monoclonal antibody, and shows antitumor activity. Siltuximab can be used in Multicentric Castleman's Disease (MCD) and COVID-19 research .
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4
4 Cited Publications
Cat. No.: HY-P7103A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth Factor; Prev. IFNB2; IFN-Beta-2; IL-6; BSF-2; interleukin-6; CDF; BSF2; interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation Factor; HSF; Truncated interleukin 6; B-Cell Stimulatory Factor 2; Interferon, Beta 2; CTL Differ
Species:  
Rat
Source:  
HEK293
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3
3 Cited Publications
Cat. No.: HY-P80723
Synonyms: IL6; IFNB2; interleukin-6; IL-6; B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2

Host:  

Rabbit

Application:  

WB, IHC-P, ELISA

Reactivity:  

Human

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2
2 Cited Publications
Cat. No.: HY-113066A
CAS No.: 7415-69-2
Purity:  ≥95.0%
Synonyms: GDP disodium salt
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K + channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .
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2
2 Cited Publications
Cat. No.: HY-P7044A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth Factor; Prev. IFNB2; IFN-Beta-2; IL-6; BSF-2; interleukin-6; CDF; BSF2; interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation Factor; HSF; Truncated interleukin 6; B-Cell Stimulatory Factor 2; Interferon, Beta 2; CTL Differentiation Factor; interleukin BSF-2; interleukin 6; Interferon Beta-2
Species:  
Human
Source:  
CHO
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2
2 Cited Publications
Cat. No.: HY-P7044G
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth Factor; Prev. IFNB2; IFN-Beta-2; IL-6; BSF-2; interleukin-6; CDF; BSF2; interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation Factor; HSF; Truncated interleukin 6; B-Cell Stimulatory Factor 2; Interferon, Beta 2; CTL Differ
Species:  
Human
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-P7223
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6R; IL-6R 1; interleukin 6 Receptor; IL-6RA; Gp80; interleukin 6 Receptor Subunit Alpha; interleukin-6 Receptor Subunit Alpha; IL-6R Subunit Alpha; Membrane Glycoprotein 80; IL-6R-Alpha; IL-1Ra; IL-6R-1; IL6RA; IL6QTL; IL-6R; IL6RQ; CD126; HIES5; IL-6 Receptor Subunit Alpha; IL6Q; CD126 Antigen
Species:  
Human
Source:  
CHO
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1
1 Cited Publications
Cat. No.: HY-P99210
CAS No.: 1007223-17-7
Synonyms: CDP 6038; OKZ

Research Areas:  

Inflammation/Immunology

Olokizumab (CDP 6038) is a humanized monoclonal antibody that targets interleukin-6 (IL-6). Olokizumab inhibits IL-6-induced STAT-3 phosphorylation. Olokizumab is used in the study of arthritis .
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1
1 Cited Publications
Cat. No.: HY-P7378
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth Factor; Prev. IFNB2; IFN-Beta-2; IL-6; BSF-2; interleukin-6; CDF; BSF2; interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation Factor; HSF; Truncated interleukin 6; B-Cell Stimulatory Factor 2; Interferon, Beta 2; CTL Differ
Species:  
Mouse
Source:  
CHO
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1
1 Cited Publications
Cat. No.: HY-P7044B
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth Factor; Prev. IFNB2; IFN-Beta-2; IL-6; BSF-2; interleukin-6; CDF; BSF2; interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation Factor; HSF; Truncated interleukin 6; B-Cell Stimulatory Factor 2; Interferon, Beta 2; CTL Differ
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P78854
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth Factor; Prev. IFNB2; IFN-Beta-2; IL-6; BSF-2; interleukin-6; CDF; BSF2; interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation Factor; HSF; Truncated interleukin 6; B-Cell Stimulatory Factor 2; Interferon, Beta 2; CTL Differ
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P700216AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL6; Hybridoma Growth Factor; Prev. IFNB2; IFN-Beta-2; IL-6; BSF-2; interleukin-6; CDF; BSF2; interleukin 6 (Interferon, Beta 2); HGF; B-Cell Differentiation Factor; HSF; Truncated interleukin 6; B-Cell Stimulatory Factor 2; Interferon, Beta 2; CTL Differ
Species:  
Mouse
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P76370
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL6ST; interleukin Receptor Beta Chain; interleukin 6 Cytokine Family Signal Transducer; Membrane Glycoprotein Gp130; interleukin-6 Receptor Subunit Beta; IL6ST Nirs Variant 5; Membrane Glycoprotein 130; IL6ST Nirs Variant 2; IL-6RB; IL6ST Nirs Variant 3
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P0064
CAS No.: 221227-05-0
Synonyms: Palmitoyl Tetrapeptide-7
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Palmitoyl Tetrapeptide-3 (Palmitoyl Tetrapeptide-7) is a synthetic peptide corresponding to amino acids 341-344 of the human immunoglobulin heavy chain, with the ability to stimulate phagocytosis. Palmitoyl tetrapeptide-3 reduces interleukin-6 (IL-6) secretion in keratinocytes and inhibits the UVB radiation-exposure inflammatory response of skin. Palmitoyl tetrapeptide-3 It also has anti-inflammatory and anti-aging effects, reducing skin wrinkles by promoting the production of elastic fibers in the papillary dermis .
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Cat. No.: HY-177063
CAS No.: 296790-70-0
Target:  

Interleukin Related

Research Areas:  

Infection Inflammation/Immunology

IL-6-IN-2 is an interleukin-6 (IL-6) inhibitor. IL-6-IN-2 binds to IL-6 at Lys66, Phe74, Gln175, Ser176, and Arg179 via π-π, π-alkyl, hydrogen bond, and hydrophobic interactions to block IL-6/IL-6R heterocomplex formation. IL-6-IN-2 exhibits low gastrointestinal absorption rate. IL-6-IN-2 can be used for the research of cytokine release syndrome, covid-19 .
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Cat. No.: HY-Y0148
CAS No.: 1679-53-4
Synonyms: NSC 15139; 10-HDAA
10-Hydroxydecanoic acid (10-HDAA) is a saturated fatty acid derived from 10-hydroxy-trans-2-decenoic acid, which can be isolated from royal jelly. 10-Hydroxydecanoic acid exhibits various biological activities, including anti-inflammatory, insecticidal, anti-malarial, and anti-Leishmania properties, as well as enhancing antigen-specific immune responses. The anti-inflammatory effects of 10-Hydroxydecanoic acid are primarily mediated by inhibiting the activation of NF-κB and the translation of interferon regulatory factor 1 (IRF-1), which reduces the production of interleukin 6 (IL-6) and nitric oxide (NO) in inflammatory cells. Additionally, 10-Hydroxydecanoic acid alleviates neuroinflammatory responses through the p53-autophagy pathway and the p53-NLRP3 pathway. Finally, 10-Hydroxydecanoic acid enhances antigen-specific immune responses by promoting the effective uptake of antigens by microfold cells .
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Cat. No.: HY-P99287
CAS No.: 468715-71-1
Synonyms: B-E8; Anti-IL-6 MAB B-E8

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Elsilimomab (B-E8) is a IgG1 monoclonal antibody against interleukin-6 (IL-6), with a KD of 22 pM and an IC50 of 1.4 nM. Elsilimomab can be used for the research of multiple myeloma, renal cell carcinoma, and rheumatoid arthritis (RA) .
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